Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Xiaole Sheng"'
Autor:
Junxuan Peng, Shengda Cao, Zhen Hu, Jiayi Zhu, Yi Zhu, Xiaole Sheng, Zuchao Cai, Rongpan Bai, Xushen Xiong, Jinghao Sheng
Publikováno v:
Environment International, Vol 191, Iss , Pp 108948- (2024)
Bisphenol A (BPA) and its substitute fluorene-9-bisphenol (BHPF) are used in consumer products; however, their toxic effects on intestinal epithelium remain largely unknown. In this study, we combined intestinal organoids and single-cell RNA sequenci
Externí odkaz:
https://doaj.org/article/9c16797344c44056b0d5ac1e2b937b68
Autor:
Cong Lv, Fengyin Li, Xiang Li, Yuhua Tian, Yue Zhang, Xiaole Sheng, Yongli Song, Qingyong Meng, Shukai Yuan, Liming Luan, Thomas Andl, Xu Feng, Baowei Jiao, Mingang Xu, Maksim V. Plikus, Xing Dai, Christopher Lengner, Wei Cui, Fazheng Ren, Jianwei Shuai, Sarah E. Millar, Zhengquan Yu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-4 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/e76adeb2c76c4a8e8ca468d031d7f0ae
Autor:
Chunlei Shao, Pengbo Lou, Ruiqi Liu, Xueyun Bi, Guilin Li, Xu Yang, Xiaole Sheng, Jiuzhi Xu, Cong Lv, Zhengquan Yu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Myoepithelial and luminal cells synergistically expand in the mammary gland during pregnancy, and this process is precisely governed by hormone-related signaling pathways. The bone morphogenetic protein (BMP) signaling pathway is now known to play cr
Externí odkaz:
https://doaj.org/article/e4819279527941328439fbb6bb74059a
Autor:
Xiaole Sheng, Ziguang Lin, Cong Lv, Chunlei Shao, Xueyun Bi, Min Deng, Jiuzhi Xu, Christian F. Guerrero-Juarez, Mengzhen Li, Xi Wu, Ran Zhao, Xu Yang, Guilin Li, Xiaowei Liu, Qingyu Wang, Qing Nie, Wei Cui, Shan Gao, Hongquan Zhang, Zhihua Liu, Yingzi Cong, Maksim V. Plikus, Christopher J. Lengner, Bogi Andersen, Fazheng Ren, Zhengquan Yu
Publikováno v:
Cell Reports, Vol 32, Iss 4, Pp 107952- (2020)
Summary: A certain number of epithelial cells in intestinal crypts are DNA damage resistant and contribute to regeneration. However, the cellular mechanism underlying intestinal regeneration remains unclear. Using lineage tracing, we show that cells
Externí odkaz:
https://doaj.org/article/8a6eed3e68c3420e9380c482b91cf220
Autor:
Cong Lv, Fengyin Li, Xiang Li, Yuhua Tian, Yue Zhang, Xiaole Sheng, Yongli Song, Qingyong Meng, Shukai Yuan, Liming Luan, Thomas Andl, Xu Feng, Baowei Jiao, Mingang Xu, Maksim V. Plikus, Xing Dai, Christopher Lengner, Wei Cui, Fazheng Ren, Jianwei Shuai, Sarah E. Millar, Zhengquan Yu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
MicroRNAs play an important role in stem cell fate and tumorigenesis. In this work, the authors show that miR-31 controls mammary stem cell self-renewal and tumorigenesis by simultaneously activating Wnt/β-catenin and repressing TGFβ signaling path
Externí odkaz:
https://doaj.org/article/ca55349c2f9c4d529171e92fed21d469
Autor:
Yuhua Tian, Xianghui Ma, Cong Lv, Xiaole Sheng, Xiang Li, Ran Zhao, Yongli Song, Thomas Andl, Maksim V Plikus, Jinyue Sun, Fazheng Ren, Jianwei Shuai, Christopher J Lengner, Wei Cui, Zhengquan Yu
Publikováno v:
eLife, Vol 6 (2017)
Intestinal regeneration and tumorigenesis are believed to be driven by intestinal stem cells (ISCs). Elucidating mechanisms underlying ISC activation during regeneration and tumorigenesis can help uncover the underlying principles of intestinal homeo
Externí odkaz:
https://doaj.org/article/1d2bccaaafe9496e8e76507d170d4c34
Lepr+ mesenchymal cells sense diet to modulate intestinal stem/progenitor cells via Leptin–Igf1 axis
Autor:
Min Deng, Christian F. Guerrero-Juarez, Xiaole Sheng, Jiuzhi Xu, Xi Wu, Kai Yao, Mengzhen Li, Xu Yang, Guilin Li, Jintao Xiao, Xiaowei Liu, Kaichun Wu, Fazheng Ren, Qing Nie, Maksim V. Plikus, Zhengquan Yu, Cong Lv
Publikováno v:
Cell research, vol 32, iss 7
Cell Res
Cell Res
Diet can impact on gut health and disease by modulating intestinal stem cells (ISCs). However, it is largely unknown if and how the ISC niche responds to diet and influences ISC function. Here, we demonstrate that Lepr(+) mesenchymal cells (MCs) surr
Autor:
Xu Yang, Jiuzhi Xu, Xiaole Sheng, Cong Lv, Pengbo Lou, Xiaoyue Duan, Chunlei Shao, Min Deng, Xi Wu, Zhengquan Yu
Publikováno v:
Food & Function. 12:10700-10713
Inflammatory bowel disease (IBD) is a chronic intestinal inflammation that is currently incurable. Increasing evidence indicates that supplementation with probiotics could improve the symptoms of IBD. It is scientifically significant to identify nove
Autor:
Bin Liang, Fazheng Ren, Xiaole Sheng, Xueyun Bi, Maksim V. Plikus, Pengbo Lou, Cong Lv, Jiuzhi Xu, Xu Yang, Ruiqi Liu, Yuhua Tian, Huiyuan Guo, Qianqian Kang, Guilin Li, Yongli Song, Bing Zhang, Qingyong Meng, Zhengquan Yu
Publikováno v:
Theranostics
Background: Brown adipose tissue (BAT) dissipates chemical energy as heat and has the potential to be a protective strategy to prevent obesity. microRNAs (miRNAs) are emerging as important posttranscriptional factors affecting the thermogenic functio
Autor:
Qingyu Wang, Jiuzhi Xu, Huiyuan Guo, Yuan Li, Xuening Hou, Fazheng Ren, Zhengquan Yu, Xiaole Sheng, Hao Zhang, Yingying Lin
Publikováno v:
Stem Cell Reports
Summary Intestinal regeneration is crucial for functional restoration after injury, and nutritional molecules can play an important role in this process. Here, we found that arachidonic acid (AA) serves as a direct proliferation promoter of intestina