Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Xiaolan Qian"'
Publikováno v:
Mathematics, Vol 12, Iss 2, p 228 (2024)
Non-consensus phenomena are widely observed in human society, but more attention is paid to consensus phenomena. One famous consensus model is the DeGroot model, and there are a series of outstanding works derived from it. By introducing the cognitio
Externí odkaz:
https://doaj.org/article/ffa587e6f8614fbc8770c6de5d4970bf
Autor:
Brajendra K. Tripathi, Meghan F. Anderman, Disha Bhargava, Luciarita Boccuzzi, Xiaolan Qian, Dunrui Wang, Marian E. Durkin, Alex G. Papageorge, Fernando J. de Miguel, Katerina Politi, Kylie J. Walters, James H. Doroshow, Douglas R. Lowy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The tumor suppressor gene DLC1 can be downregulated in cancers through genetic and non-genetic mechanisms. Here, the authors show cytoplasmic EZH2 can directly methylate and destabilize the DLC1 protein, and EZH2 inhibition can increase the DLC1 prot
Externí odkaz:
https://doaj.org/article/7176f11d2bb2458e8f04d65843a147be
Autor:
Beatriz Sanchez-Solana, Dunrui Wang, Xiaolan Qian, Parthibane Velayoudame, Dhirendra K. Simanshu, Jairaj K. Acharya, Douglas R. Lowy
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-18 (2021)
Abstract Background DLC1, a tumor suppressor gene that is downregulated in many cancer types by genetic and nongenetic mechanisms, encodes a protein whose RhoGAP and scaffolding activities contribute to its tumor suppressor functions. The role of the
Externí odkaz:
https://doaj.org/article/a367e3987a09471bbf53fecd07797e4f
Autor:
Bo Hu, Xiaolan Qian, Ping Qian, Guangtao Xu, Xin Jin, Deqing Chen, Long Xu, Jie Tang, Wenjing Wu, Wanlu Li, Jin Zhang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
CTRP6, a member of the C1q/TNF-related protein (CTRP) family, has gained increasing scientific interest because of its regulatory role in tumor progression. Previous studies have shown that CTRP6 is closely involved in regulating various pathophysiol
Externí odkaz:
https://doaj.org/article/38317650cfbe4ac4ae72d9c236682890
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 241, Iss , Pp 113790- (2022)
Environmental pollution often releases multiple contaminants resulting in as yet largely uncharacterized additive toxicities. Cadmium (Cd) is a widespread pollutant that induces nephrotoxicity in animal models and humans. However, the combined effect
Externí odkaz:
https://doaj.org/article/94ce514d2fe04f1d9a4fb90e0e94d98d
Autor:
Bo Hu, Guangtao Xu, Xin Jin, Deqing Chen, Xiaolan Qian, Wanlu Li, Long Xu, Jia Zhu, Jie Tang, Xiuhui Jin, Jian Hou
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Primary pulmonary hypertension (PPH) is a life-threatening disease associated with increased mortality. The urea cycle pathway plays a major role in PPH severity and treatment response. Little is known about the association of the blood u
Externí odkaz:
https://doaj.org/article/d1d711549d6a48809231b1141d5a6375
Autor:
Jie Tang, Bo Hu, Huaping Zheng, Xiaolan Qian, Yi Zhang, Jia Zhu, Guangtao Xu, Deqing Chen, Xin Jin, Wanlu Li, Long Xu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 221, Iss , Pp 112423- (2021)
Tetrabromodiphenyl ether (BDE-47) is widely used as commercial flame retardants that can be released into the environment and finally enter human body through the food chain. It has been identified to generate neurotoxicity, but little is known about
Externí odkaz:
https://doaj.org/article/76bee8ac33dc4b98869fe693416919b7
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 5, Pp 1840-1850 (2018)
Background/Aims: Human hedgehog-interacting protein (HHIP) is a negative regulator of the hedgehog (HH) signaling pathway. It is deregulated in gastric cancer. The underlying molecular mechanism of HHIP-induced inhibition of HH signaling remains to b
Externí odkaz:
https://doaj.org/article/4a9e084705c34187bb75b14c0dd2a4ce
Publikováno v:
Bio-Protocol, Vol 3, Iss 18 (2013)
Preparation of primary cultures of embryo fibroblasts from genetically engineered mouse strains can provide a valuable resource for analyzing the consequences of genetic alterations at the cellular level. Mouse embryo fibroblasts (MEFs) have been par
Externí odkaz:
https://doaj.org/article/9b0bcdfb2507479b9d7223b6aa084d8a
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61262 (2013)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is often used as a stable housekeeping marker for constant gene expression. However, the transcriptional levels of GAPDH may be highly up-regulated in some cancers, including non-small cell lung cancer
Externí odkaz:
https://doaj.org/article/6baf621439c0423c99e4665ad1871035