Výsledky vyhledávání - "Xiaokuan Zhu"

Akademický článek

EGFR mutations induce the suppression of CD8+ T cell and anti-PD-1 resistance via ERK1/2-p90RSK-TGF-β axis in non-small cell lung cancer

Autor: Huayan Huang, Xiaokuan Zhu, Yongfeng Yu, Ziming Li, Yi Yang, Liliang Xia, Shun Lu

Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)

Abstract Background Non-small cell lung cancer (NSCLC) patients with EGFR mutations exhibit an unfavorable response to immune checkpoint inhibitor (ICI) monotherapy, and their tumor microenvironment (TME) is usually immunosuppressed. TGF-β plays an

Externí odkaz: https://doaj.org/article/840164fb6bfa46518836602d2f8cc99e

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Landscape of Savolitinib Development for the Treatment of Non-Small Cell Lung Cancer with MET Alteration-A Narrative Review

Autor: Xiaokuan Zhu, Yao Lu, Shun Lu

Publikováno v: Cancers. 14(24)

Non-small cell lung cancer (NSCLC) is increasingly being treated with targeted therapies. Savolitinib (Orpathys®) is highly selective mesenchymal epithelial transition (MET)–tyrosine kinase inhibitor (TKI), which is conditionally approved in China

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530ac1f264419eac1db7ff35b1f52ab4
https://pubmed.ncbi.nlm.nih.gov/36551608

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