Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Xiaojing MAO"'
Publikováno v:
工程科学学报, Vol 46, Iss 1, Pp 23-32 (2024)
Laser-induced breakdown spectroscopy (LIBS) is a type of atomic emission spectroscopy for multi-element analysis. This analysis is rapid and accurate, has a simple sample preparation, and realizes remote analysis. However, the accuracy of the qualita
Externí odkaz:
https://doaj.org/article/d63c8f04a1ab4613aed88b4d4a8c4e38
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Methylene blue (MB) is a century-old medicine, a laboratory dye, and recently shown as a premier antioxidant that combats ROS-induced cellular aging in human skins. Given MB’s molecular structure and light absorption properties, we hypothe
Externí odkaz:
https://doaj.org/article/1413f1dd95c34da8bac22324d41508fd
Autor:
Xiaojing Mao, Zheng-Mei Xiong, Huijing Xue, Markus A. Brown, Yantenew G. Gete, Reynold Yu, Linlin Sun, Kan Cao
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5499
Hutchinson-Gilford progeria syndrome (HGPS) is a detrimental premature aging disease caused by a point mutation in the human LMNA gene. This mutation results in the abnormal accumulation of a truncated pre-lamin A protein called progerin. Among the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8385d97871ed10a2d17d9518725c96ee
https://pubmed.ncbi.nlm.nih.gov/35628310
https://pubmed.ncbi.nlm.nih.gov/35628310
Autor:
Xiaojing Mao, John P. Fisher, Bhushan Mahadik, Luke W. Koblan, David R. Liu, Kan Cao, Yantenew G. Gete, Mason Trappio
Publikováno v:
Aging Cell
Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder with features of accelerated aging. The majority of HGPS cases are caused by a de novo point mutation in the LMNA gene (c.1824C>T; p.G608G) resulting in progerin, a toxic lamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6387edb7cbc2ae2c6718041d219ae67d
https://doi.org/10.1111/acel.13388
https://doi.org/10.1111/acel.13388
Autor:
Francis S. Collins, Ji Young Choi, Richard J. Hodes, Zheng-Mei Xiong, Linlin Sun, Kan Cao, Jeffrey Chiang, Xiaojing Mao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance In the classic view, telomerase is silenced in terminally differentiated cells and its reactivation supports immortalization and unlimited growth of most cancers. Here, we determine the involvement of telomerase during replicative senesc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1403692832f6806180864639a239d3c6
http://europepmc.org/articles/PMC6754593
http://europepmc.org/articles/PMC6754593
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Methylene blue (MB) is a century-old medicine, a laboratory dye, and recently shown as a premier antioxidant that combats ROS-induced cellular aging in human skins. Given MB’s molecular structure and light absorption properties, we hypothesize that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f569af42d3ec579397f3e97ae5baaa
https://doi.org/10.1038/s41598-021-89970-2
https://doi.org/10.1038/s41598-021-89970-2
Autor:
Sean P. Doherty, Chad Krilow, Narisu Narisu, Urraca Tavarez, Luke W. Koblan, Zheng-Mei Xiong, Jonathan D. Brown, Lindsay M. Davison, Yantenew G. Gete, Leslie B. Gordon, Francis S. Collins, Quanhu Sheng, Christine D. Wilson, Michael R. Erdos, Wayne A. Cabral, Kan Cao, Jonathan M. Levy, Charles Y. Lin, David R. Liu, Xiaojing Mao, Gregory A. Newby
Publikováno v:
Signal Transduction and Targeted Therapy
Hutchinson–Gilford progeria syndrome (HGPS or progeria) is typically caused by a dominant-negative C•G-to-T•A mutation (c.1824 C>T; p.G608G) in LMNA, the gene that encodes nuclear lamin A. This mutation causes RNA mis-splicing that produces pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd3488e50d3a070f78b7a501fbd1168
https://pubmed.ncbi.nlm.nih.gov/33863871
https://pubmed.ncbi.nlm.nih.gov/33863871
Publikováno v:
Chemosphere. 186:466-474
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently used pharmaceuticals in animals. In the current study, the biotransformation of five NSAIDs by pig liver microsomes (PLMs) was studied. The pseudo-first-order kinetics mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8c2731f57d743e42db2e9212deb59a
https://doi.org/10.1016/j.chemosphere.2017.08.026
https://doi.org/10.1016/j.chemosphere.2017.08.026
Publikováno v:
Human Molecular Genetics. 26:3253-3270
Fibroblast Growth Factor (FGF) signaling promotes self-renewal in progenitor cells by encouraging proliferation and inhibiting cellular senescence. Yet, these beneficial effects can be hijacked by disease-causing mutations in FGF receptor (FGFR) duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b80b2856af9c4a5f9d55e719ae7c50
https://doi.org/10.1093/hmg/ddx209
https://doi.org/10.1093/hmg/ddx209