Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Xiaojing, Lin"'
Autor:
Cara E. Toscan, Hannah McCalmont, Amir Ashoorzadeh, Xiaojing Lin, Zhe Fu, Louise Doculara, Hansen J. Kosasih, Roxanne Cadiz, Anthony Zhou, Sarah Williams, Kathryn Evans, Faezeh Khalili, Ruilin Cai, Kristy L. Yeats, Andrew J. Gifford, Russell Pickford, Chelsea Mayoh, Jinhan Xie, Michelle J. Henderson, Toby N. Trahair, Adam V. Patterson, Jeff B. Smaill, Charles E. de Bock, Richard B. Lock
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy that expresses high levels of the enzyme aldo-keto reductase family 1 member C3 (AKR1C3). To exploit this finding, we developed a novel prodrug, ACHM-025,
Externí odkaz:
https://doaj.org/article/6345a011fd5e4b7dbeced8196c76971a
Autor:
Kaifeng Guo, Yali Han, Shuang Liu, Hang Sun, Xiaojing Lin, Shaoling Yang, Yining Gao, Haibing Chen
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Purpose Our objective was to ascertain the most recent prevalence and trends of hyperuricemia among adolescents, stratified by sex and race/ethnicity subgroups, as well as to investigate potential risk factors associated with hyperuricemia i
Externí odkaz:
https://doaj.org/article/42b689ce43514ee69cdc7c01c3f76803
Autor:
Biyan Ni, Ziqi Yang, Tian Zhou, Hong Zhou, Yang Zhou, Shiya Lin, Huiyi Xu, Xiaojing Lin, Wei Yi, Chang He, Xialin Liu
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract The microglia-mediated neuroinflammation have been shown to play a crucial role in the ocular pathological angiogenesis process, but specific immunotherapies for neovascular ocular diseases are still lacking. This study proposed that targeti
Externí odkaz:
https://doaj.org/article/614d073dc28a47e6893292afd931f43a
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
ObjectiveObservational studies have found associations between reproductive factors and bone density in women. However, the causal relationships are not well understood. This study aims to investigate whether various reproductive factors are causally
Externí odkaz:
https://doaj.org/article/0571d546ea0047a4970b5570cb7c0678
Autor:
Shuang Liu, Xiaojing Lin, Minghao Tao, Qi Chen, Hang Sun, Yali Han, Shaoling Yang, Yining Gao, Shen Qu, Haibing Chen
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background Obesity is associated with elevated serum uric acid (SUA) levels and frequent gout flares. Losing weight can reduce the SUA level and gout flares. The effect of orlistat on SUA levels and gout flares in patients with overweight/ob
Externí odkaz:
https://doaj.org/article/befe9935a2064a67accd173d83a7aef1
Autor:
Xiaojing Lin, Qiang Sun, Yang Cao, Zi Li, Cuiling Xu, Jun Liu, Jingdong Song, Kun Qin, Yong Zhang, Jianfang Zhou
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1331 (2024)
Enteroviruses have been a historical concern since the identification of polioviruses in humans. Wild polioviruses have almost been eliminated, while multiple species of non-polio enteroviruses and their variants co-circulate annually. To date, at le
Externí odkaz:
https://doaj.org/article/31629c87ad99463ba645aa689e67405b
Autor:
Guojun Hou, Nan Shen, Zhizhong Ye, Huihua Ding, Zhihua Yin, Dai Dai, Xinyi Zhu, Yutong Zhang, Yashuo Chen, Yiwei Shen, Xiaojing Lin, Ling-Hua Zou
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss 1 (2024)
Objectives Systemic lupus erythematosus (SLE) is a highly heterogeneous disease, and B cell abnormalities play a central role in the pathogenesis of SLE. Long non-coding RNAs (lncRNAs) have also been implicated in the pathogenesis of SLE. The express
Externí odkaz:
https://doaj.org/article/a8d171a8d50247508d6b1cc4bf7e9e45
Autor:
Shaoling Yang, Xiaojing Lin, Yining Gao, Nan Liang, Yali Han, Hang Sun, Shen Qu, Haibing Chen
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 16 (2024)
Background: Ultrasound (US) has a high sensitivity in detecting monosodium urate (MSU) deposition in gout patients. However, the value of US in predicting gout flares has been reported only in a few monocentric studies. Objective: To investigate the
Externí odkaz:
https://doaj.org/article/104d413a6a894b34998940cb67790ea3
Autor:
Xiaojing Lin, Zhaojie Wang, Shoufu Cao, Yuying Hu, Siyuan Liu, Xiaodong Chen, Hongyu Chen, Xingheng Zhang, Shuxian Wei, Hui Xu, Zhi Cheng, Qi Hou, Daofeng Sun, Xiaoqing Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Layered double hydroxides are promising candidates for the electrocatalytic oxygen evolution reaction. Unfortunately, their catalytic kinetics and long-term stabilities are far from satisfactory compared to those of rare metals. Here, we inv
Externí odkaz:
https://doaj.org/article/d11c5b7dfb26410d8f911c570110dcaf
Publikováno v:
Pathogens, Vol 13, Iss 8, p 711 (2024)
Enteroviruses (EVs and RVs) are prevalent worldwide and cause various diseases in humans, of which the VP1-pocket is a target of antivirals, with a lipid molecule as a pocket factor to stabilize the virion. However, the characterization of the struct
Externí odkaz:
https://doaj.org/article/8cfda5f0a25342e2b8bd9ed61f754171