Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Xiaojie Xian"'
Autor:
Xiaojie Xian, Roksana Moraghebi, Henrik Löfvall, Anders Fasth, Kim Henriksen, Johan Richter, Niels-Bjarne Woods, Ilana Moscatelli
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-9 (2020)
Abstract Background Infantile malignant osteopetrosis (IMO) is an autosomal recessive disorder characterized by non-functional osteoclasts and a fatal outcome early in childhood. About 50% of patients have mutations in the TCIRG1 gene. Methods IMO iP
Externí odkaz:
https://doaj.org/article/cc0206baf35e46ab9cc9094f329d2a6c
Autor:
Hongzhe Li, Hooi-Ching Lim, Dimitra Zacharaki, Xiaojie Xian, Keane J.G. Kenswil, Sandro Bräunig, Marc H.G.P. Raaijmakers, Niels-Bjarne Woods, Jenny Hansson, Stefan Scheding
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Human bone marrow stromal cells (BMSC) are key elements of the hematopoietic environment and they play a central role in bone and bone marrow physiology. However, how key stromal cell functions are regulated is largely unknown. We analyzed the role o
Externí odkaz:
https://doaj.org/article/112ede8630034c80ae41aed380c93728
Autor:
Laura Tarnawski, Xiaojie Xian, Gustavo Monnerat, Iain C Macaulay, Daniela Malan, Andrew Borgman, Sean M Wu, Bernd K Fleischmann, Stefan Jovinge
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135880 (2015)
In contrast to mature cardiomyocytes which have limited regenerative capacity, pluripotent stem cells represent a promising source for the generation of new cardiomyocytes. The tendency of pluripotent stem cells to form teratomas and the heterogeneit
Externí odkaz:
https://doaj.org/article/7f544021333c48dd93c441c2c22e1878
Autor:
Annica Pontén, Stuart Walsh, Daniela Malan, Xiaojie Xian, Susanne Schéele, Laura Tarnawski, Bernd K Fleischmann, Stefan Jovinge
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82403 (2013)
Purification of cardiomyocytes from the embryonic mouse heart, embryonic stem (ES) or induced pluripotent stem cells (iPS) is a challenging task and will require specific isolation procedures. Lately the significance of surface markers for the isolat
Externí odkaz:
https://doaj.org/article/9634837056cc484392383db13d4358cf
Autor:
Yvonne Fischer, Elvira Ganic, Jacqueline Ameri, Xiaojie Xian, Martina Johannesson, Henrik Semb
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Pluripotency and self-renewal of human embryonic stem cells (hESCs) is mediated by a complex interplay between extra- and intracellular signaling pathways, which regulate the expression of pluripotency-specific transcription factors. The homeodomain
Externí odkaz:
https://doaj.org/article/982d42a0745949a69e9cc6d68f204847
Autor:
Ilana Moscatelli, Kim Henriksen, Niels-Bjarne Woods, Anders Fasth, Henrik Löfvall, Johan Richter, Xiaojie Xian, Roksana Moraghebi
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-9 (2020)
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-9 (2020)
Background Infantile malignant osteopetrosis (IMO) is an autosomal recessive disorder characterized by non-functional osteoclasts and a fatal outcome early in childhood. About 50% of patients have mutations in the TCIRG1 gene. Methods IMO iPSCs were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423c18b404f6b3ad595f8bd82c2411a5
http://europepmc.org/articles/PMC7227215
http://europepmc.org/articles/PMC7227215
Autor:
Hongzhe, Li, Hooi-Ching, Lim, Dimitra, Zacharaki, Xiaojie, Xian, Keane J G, Kenswil, Sandro, Bräunig, Marc H G P, Raaijmakers, Niels-Bjarne, Woods, Jenny, Hansson, Stefan, Scheding
Publikováno v:
Haematologica
Human bone marrow stromal cells (BMSC) are key elements of the hematopoietic environment and they play a central role in bone and bone marrow physiology. However, how key stromal cell functions are regulated is largely unknown. We analyzed the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e2f2eed3d0195a2b4db6c1e6ffd0bf9
https://pubmed.ncbi.nlm.nih.gov/31371413
https://pubmed.ncbi.nlm.nih.gov/31371413
Autor:
John R. Couchman, Claire Chaussade, James R. Whiteford, Bart Vanhaesebroeck, Sussan Nourshargh, Xiaojie Xian
Publikováno v:
Molecular Biology of the Cell
The proteoglycan syndecan-2 is a novel ligand for the tyrosine phosphatase receptor CD148, an interaction that stimulates a signaling pathway leading to integrin-mediated cell adhesion. The pathway involves SRC and PI3 kinases and is an example of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6301029a0e9d0854a7c321f184cfe2f
https://doi.org/10.1091/mbc.e11-02-0099
https://doi.org/10.1091/mbc.e11-02-0099
Autor:
Andrew Borgman, Gustavo Monnerat, Stefan Jovinge, Laura Tarnawski, Xiaojie Xian, Sean M. Wu, Bernd K. Fleischmann, Iain C. Macaulay, Daniela Malan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0135880 (2015)
PLoS ONE, Vol 10, Iss 8, p e0135880 (2015)
In contrast to mature cardiomyocytes which have limited regenerative capacity, pluripotent stem cells represent a promising source for the generation of new cardiomyocytes. The tendency of pluripotent stem cells to form teratomas and the heterogeneit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023c280da5acd6bb761722cd2b2349d4
http://europepmc.org/articles/PMC4556377
http://europepmc.org/articles/PMC4556377
Autor:
Anders Ståhlberg, Joakim Håkansson, Xiaojie Xian, Holger Gerhardt, Henrik Semb, Per Lindblom, Christer Betsholtz
Publikováno v:
Journal of Clinical Investigation. 116:642-651
Previously we observed that neural cell adhesion molecule (NCAM) deficiency in beta tumor cells facilitates metastasis into distant organs and local lymph nodes. Here, we show that NCAM-deficient beta cell tumors grew leaky blood vessels with perturb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a124e58fbcf7cc545424dd02d8c0dcc0
https://doi.org/10.1172/jci25705
https://doi.org/10.1172/jci25705