Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Xiaoji Wu"'
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3227-3241 (2017)
The hypothalamus is one of the most complex brain structures involved in homeostatic regulation. Defining cell composition and identifying cell-type-specific transcriptional features of the hypothalamus is essential for understanding its functions an
Externí odkaz:
https://doaj.org/article/b2424a6835ec4a51ad89dc8e709410ea
Autor:
Jan M. Suski, Nalin Ratnayeke, Marcin Braun, Tian Zhang, Vladislav Strmiska, Wojciech Michowski, Geylani Can, Antoine Simoneau, Konrad Snioch, Mikolaj Cup, Caitlin M. Sullivan, Xiaoji Wu, Joanna Nowacka, Timothy B. Branigan, Lindsey R. Pack, James A. DeCaprio, Yan Geng, Lee Zou, Steven P. Gygi, Johannes C. Walter, Tobias Meyer, Piotr Sicinski
Publikováno v:
Nature
Entry of mammalian cells into DNA synthesis (S-phase) represents a key event in cell division(1). According to the current cell-cycle models, the Cdc7 kinase constitutes an essential and rate-limiting trigger of DNA replication, acting together with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45715658eede1ab74ef28982d4c5fa8a
https://doi.org/10.1038/s41586-022-04698-x
https://doi.org/10.1038/s41586-022-04698-x
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific reports, vol 7, iss 1
Scientific Reports
Scientific reports, vol 7, iss 1
Autophagy is a bulk cell-degradation process that occurs through the lysosomal machinery, and many reports have shown that it participates in microbial pathogenicity. However, the role of autophagy in Clostridium difficile infection (CDI), the leadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cca011ed18656a98edb267e95ca22b0
http://link.springer.com/article/10.1038/s41598-017-11336-4
http://link.springer.com/article/10.1038/s41598-017-11336-4
Publikováno v:
Genes & Development. 31:511-523
To understand mammalian active DNA demethylation, various methods have been developed to map the genomic distribution of the demethylation intermediates 5-formylcysotine (5fC) and 5-carboxylcytosine (5caC). However, the majority of these methods requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad4c34cda1950932cb2046c279fa78b
https://doi.org/10.1101/gad.294843.116
https://doi.org/10.1101/gad.294843.116
Publikováno v:
Nature Protocols. 11:1081-1100
A complete understanding of the function of the ten-eleven translocation (TET) family of dioxygenase-mediated DNA demethylation requires new methods to quantitatively map oxidized 5-methylcytosine (5mC) bases at high resolution. We have recently deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32cfa85c27e1324678d97dbba0b626fb
https://doi.org/10.1038/nprot.2016.069
https://doi.org/10.1038/nprot.2016.069
Publikováno v:
Nature cell biology. 21(7)
Totipotency refers to the ability of a cell to generate all of the cell types of an organism. Unlike pluripotency, the establishment of totipotency is poorly understood. In mouse embryonic stem cells, Dux drives a small percentage of cells into a tot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36f5fca990919f5f586fc22e932bfb6
https://pubmed.ncbi.nlm.nih.gov/31209294
https://pubmed.ncbi.nlm.nih.gov/31209294
Publikováno v:
Nature reviews. Genetics. 18(9)
In mammals, DNA methylation in the form of 5-methylcytosine (5mC) can be actively reversed to unmodified cytosine (C) through TET dioxygenase-mediated oxidation of 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316fdaee362993e2845577e419f2e838
https://pubmed.ncbi.nlm.nih.gov/28555658
https://pubmed.ncbi.nlm.nih.gov/28555658
Publikováno v:
Nature biotechnology
Active DNA demethylation in mammals involves TET-mediated iterative oxidation of 5-methylcytosine (5mC)/5-hydroxymethylcytosine (5hmC) and subsequent excision repair of highly oxidized cytosine bases 5-formylcytosine (5fC)/5-carboxylcytosine (5caC) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78652ede761333093c1a8ac667f75d5b
https://doi.org/10.1038/nbt.3073
https://doi.org/10.1038/nbt.3073
Autor:
Yi Zhang, Xiaoji Wu, Atsuo Ogura, Kumiko Iwabuchi, Falong Lu, Huihan Wang, William H. Press, Li Shen, Shogo Matoba, Lin Yang, Jeannie T. Lee, Kimiko Inoue, Lan Jiang
Publikováno v:
Cell Stem Cell. 23:343-354.e5
Animal cloning can be achieved through somatic cell nuclear transfer (SCNT), although the live birth rate is relatively low. Recent studies have identified H3K9me3 in donor cells and abnormal Xist activation as epigenetic barriers that impede SCNT. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7df1f84c73f6b749f020a11a49fa9f
https://doi.org/10.1016/j.stem.2018.06.008
https://doi.org/10.1016/j.stem.2018.06.008
Autor:
Kathrin Schirner, Xiaoji Wu, Simon Ringgaard, Brigid M. Davis, Matthew K. Waldor, Martha A. Zepeda-Rivera
Publikováno v:
Proceedings of the National Academy of Sciences. 111
Bacterial chemotaxis proteins are organized into ordered arrays. In peritrichous organisms, such as Escherichia coli, stochastic assembly processes are thought to account for the placement of chemotaxis arrays, which are nonuniformly distributed. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad6b28a131286167677c5fbc97f5064
https://doi.org/10.1073/pnas.1315722111
https://doi.org/10.1073/pnas.1315722111