Výsledky vyhledávání - "Xiaohui Tracey Wei"

Animal pharmacokinetics/pharmacodynamics (PK/PD) infection models for clinical development of antibacterial drugs: lessons from selected cases

Autor: Jason N Moore, Lucas Poon, Sonia Pahwa, Timothy Bensman, Xiaohui (Tracey) Wei, Zhixia Yan Danielsen, Seong Jang

Publikováno v: Journal of Antimicrobial Chemotherapy. 78:1337-1343

In the wake of emerging antimicrobial resistance, antibacterial drug development has become more critical. At the same time, development of antibacterial drugs targeting specific pathogens or resistance phenotypes that may have low prevalence present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45c5b0cc0b191103ac49602bbeb67aa9
https://doi.org/10.1093/jac/dkad114

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Semimechanistic Modeling of Eravacycline Pharmacodynamics Using In Vitro Time-Kill Data with MIC Incorporated in an Adaptive Resistance Function

Autor: Timothy J Bensman, Xiaohui Tracey Wei, Jason N. Moore, Ken Nguyen

Publikováno v: Antimicrob Agents Chemother

Effective bacterial infection eradication requires not only potent antibacterial agents but also proper dosing strategies. Current practices generally utilize point estimates of the effects of therapeutic agents, even though the actual kinetics of ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07663f5d04bc5037c04c0f1306a4d99
https://europepmc.org/articles/PMC7449204/

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