Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Xiaohui Pu"'
Publikováno v:
Molecules, Vol 29, Iss 8, p 1769 (2024)
The aim of this study was to develop cholic-acid-stabilized itraconazole nanosuspensions (ITZ-Nanos) with the objective of enhancing drug dissolution and oral absorption. A laboratory-scale microprecipitation–high-pressure homogenization method was
Externí odkaz:
https://doaj.org/article/9600efcf731a4227aed3c9ef37ffae43
Autor:
Jiejian Kou, Minghui Wang, Junzhuo Shi, Haiyu Zhang, Xiaohui Pu, Shiyong Song, Cuiling Yang, Yi Yan, Yvonne Döring, Xinmei Xie, Xiaobin Pang
Publikováno v:
ACS Omega, Vol 6, Iss 10, Pp 6654-6662 (2021)
Externí odkaz:
https://doaj.org/article/b82105e2991845b9ae0bd45631e0d947
Autor:
Yunfeng Zhou, Chunli Wang, Jiejian Kou, Minghui Wang, Xuli Rong, Xiaohui Pu, Xinmei Xie, Guang Han, Xiaobin Pang
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 1378-1387 (2021)
Context Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury. Bianliang ziyu, a variety of Chrysanthemum morifolium Ramat. (Asteraceae), has potential hepatoprotective effect. However, the mechanism is not clear yet. Object
Externí odkaz:
https://doaj.org/article/52586ce8f2364b6095bf1cf736a90b13
Autor:
Sheng Chang, Yanfei Wang, Tianyi Zhang, Xiaohui Pu, Lanlan Zong, Heyun Zhu, Luling Zhao, Bo Feng
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The toxicity and side effects of traditional chemotherapeutic drugs are the main causes of chemotherapy failure. To improve the specificity and selectivity of chemotherapeutic drugs for tumor cells, a novel redox-sensitive polymer prodrug, polyethyle
Externí odkaz:
https://doaj.org/article/011c7f0eda3d429684540cf53d1b4588
Autor:
Qi Yuan, Yanling Wang, Rufeng Song, Xianqiao Hou, Keke Yu, Jiaojiao Zheng, Juanmei Zhang, Xiaohui Pu, Jihong Han, Lanlan Zong
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The pharmacokinetic profile of a drug can be different when delivered as a nanosuspension compared with a true solution, which may in turn affect the therapeutic effect of the drug. The goal of this study was to prepare itraconazole nanosuspensions (
Externí odkaz:
https://doaj.org/article/aa49282db13b4cf7bd031cd410892be0
Autor:
Lanlan Zong, Yonghui Qiao, Tingting Qin, Qi Yuan, Xiaohui Pu, Rufeng Song, Zhiqiang Yu, Qingbing Zeng, Zhihao Wei, Juan Du, Shaofeng Duan
Publikováno v:
Chinese Chemical Letters. 32:2877-2881
Tumor drug resistance and systemic side effects of chemotherapeutic drugs are the main reasons for the failure of cancer treatment. In recent years, it was found that some natural active ingredients can reverse MDR and regulate body immunity to enhan
Publikováno v:
ChemistrySelect. 7
Autor:
Shiyong Song, Jiejian Kou, Hai-Yu Zhang, Cuiling Yang, Xiaobin Pang, Yvonne Döring, Xinmei Xie, Minghui Wang, Jun-Zhuo Shi, Yi Yan, Xiaohui Pu
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 10, Pp 6654-6662 (2021)
Kou, Jiejian; Wang, Minghui; Shi, Junzhuo; Zhang, Haiyu; Pu, Xiaohui; Song, Shiyong; Yang, Cuiling; Yan, Yi; Döring, Yvonne; Xie, Xinmei; Pang, Xiaobin (2021). Curcumin Reduces Cognitive Deficits by Inhibiting Neuroinflammation through the Endoplasmic Reticulum Stress Pathway in Apolipoprotein E4 Transgenic Mice. ACS Omega, 6(10), pp. 6654-6662. American Chemical Society 10.1021/acsomega.0c04810
ACS Omega, Vol 6, Iss 10, Pp 6654-6662 (2021)
Kou, Jiejian; Wang, Minghui; Shi, Junzhuo; Zhang, Haiyu; Pu, Xiaohui; Song, Shiyong; Yang, Cuiling; Yan, Yi; Döring, Yvonne; Xie, Xinmei; Pang, Xiaobin (2021). Curcumin Reduces Cognitive Deficits by Inhibiting Neuroinflammation through the Endoplasmic Reticulum Stress Pathway in Apolipoprotein E4 Transgenic Mice. ACS Omega, 6(10), pp. 6654-6662. American Chemical Society 10.1021/acsomega.0c04810
Apolipoprotein E4 (ApoE4) is the main genetic risk factor for Alzheimer's disease (AD), but the exact way in which it causes AD remains unclear. Curcumin is considered to have good therapeutic potential for AD, but its mechanism has not been clarifie
Autor:
Xiaohui Pu, Xinmei Xie, Xiaobin Pang, Xuli Rong, Jiejian Kou, Guang Han, Minghui Wang, Yunfeng Zhou, Chunli Wang
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 1378-1387 (2021)
Pharmaceutical Biology
article-version (VoR) Version of Record
Pharmaceutical Biology
article-version (VoR) Version of Record
Context Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury. Bianliang ziyu, a variety of Chrysanthemum morifolium Ramat. (Asteraceae), has potential hepatoprotective effect. However, the mechanism is not clear yet. Object
Publikováno v:
International journal of nanomedicine. 17
Juan Du,1 Lanlan Zong,2 Mengmeng Li,2 Keke Yu,2 Yonghui Qiao,3 Qi Yuan,2 Xiaohui Pu2 1Department of Pharmacy, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan, 450003, Peopleâs Republic of China; 2Institute of Pharmacy, S