Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Xiaohuan Yuan"'
Autor:
Zhiqin Cao, Keke Zhang, Jingruo Liu, Yu Pan, Jiayi Shi, Luxin Li, Xiaocan Sun, Shiqi Li, Xiaohuan Yuan, Dan Wu
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-11 (2024)
Abstract Background Skin fibrosis affects the normal function of the skin. TGF-β1 is a key cytokine that affects organ fibrosis. The latency-associated peptide (LAP) is essential for TGF-β1 activation. We previously constructed and prepared truncat
Externí odkaz:
https://doaj.org/article/53938f1a717f4ade854d139076ae6949
Autor:
Luxin Li, Yucen Dai, Dan Ke, Jieting Liu, Peijian Chen, Dong Wei, Tongtong Wang, Yanjie Teng, Xiaohuan Yuan, Zhen Zhang
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are the most serious and common diabetes-associated complications. DN and DR are all highly prevalent and dangerous global diseases, but the underlying mechanism remains to be elucidated. Ferrop
Externí odkaz:
https://doaj.org/article/09f257d2b0784ce3a9002f9f65ffd169
Autor:
Yan Wu, Meng Su, Shihao Zhang, Lan Xiao, Yin Xiao, Mengya Zhang, Ying Bei, Meiyun Li, Fan Zhang, Qi Yuan, Shiyong Wu, Jianyong Liu, Haitao Li, Xiaohuan Yuan, Meng Li, Yulin Li, Jie Gao
Publikováno v:
Materials & Design, Vol 230, Iss , Pp 111960- (2023)
The application of gelatin hydrogels is hampered by their poor mechanical properties, which are unfavorable for debridement and diabetic wound healing. Herein, bovine serum albumin (BSA)-bridged gelatin hydrogels biopotentiated by bone marrow mesench
Externí odkaz:
https://doaj.org/article/ef460a063e654c658034bf6487e06330
Autor:
Xudong Song, Jiayi Shi, Jieting Liu, Yong Liu, Yang Yu, Yufei Qiu, Zhiqin Cao, Yu Pan, Xiaohuan Yuan, Yanhui Chu, Dan Wu
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-15 (2022)
Abstract Background Liver fibrosis is a progressive liver injury response. Transforming growth factor β1 (TGF-β1) is oversecreted during liver fibrosis and promotes the development of liver fibrosis. Therapeutic approaches targeting TGF-β1 and its
Externí odkaz:
https://doaj.org/article/9258887cfd62423ab08d31129e13a465
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundsAlcoholic hepatitis (AH) is a major health problem worldwide. There is increasing evidence that immune cells, iron metabolism and copper metabolism play important roles in the development of AH. We aimed to explore biomarkers that are co-a
Externí odkaz:
https://doaj.org/article/08809642ae1a4618baa7ffae4027f09c
Autor:
Hua Liu, Wendan Chen, Yuhong Chai, Wenchao Liu, Haixia Chen, Lei Sun, Xiaowei Tang, Chang Luo, Dongliang Chen, Xi Cheng, Fengjun Wang, Xiaohuan Yuan, Conglin Huang
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
‘Taihang Mingzhu’ is the hybrid offspring of Opisthopappus taihangensis, and it has an excellent characteristic of whole-plant fragrance. At present, the genes and metabolites involved in the synthesis of its aromatic compounds are unknown becaus
Externí odkaz:
https://doaj.org/article/8285fb25165745dea623aabe656b7ed1
Publikováno v:
PeerJ, Vol 10, p e12797 (2022)
Background Cardiac fibrosis refers to the abnormal accumulation of extracellular matrix in the heart, which leads to the formation of cardiac scars. It causes systolic and diastolic dysfunction, and ultimately leads to cardiac dysfunction and arrhyth
Externí odkaz:
https://doaj.org/article/41696814c83242e38404a7841ecc8223
Autor:
Chunyin Tang, Meng Wang, Jieting Liu, Chunlei Zhang, Luxin Li, Yan Wu, Yanhui Chu, Dan Wu, Haifeng Liu, Xiaohuan Yuan
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3270 (2022)
Excessive accumulation of the extracellular matrix (ECM) is a crucial pathological process in chronic kidney diseases, such as diabetic nephropathy, etc. The underlying mechanisms of how to decrease ECM deposition to improve diabetic nephropathy rema
Externí odkaz:
https://doaj.org/article/74baf1ca929c4b2da61b8db9697a774d
Autor:
Chunyin Tang, Jieting Liu, Chunsong Yang, Jun Ma, Xuejiao Chen, Dongwen Liu, Yao Zhou, Wei Zhou, Yunzhu Lin, Xiaohuan Yuan
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1636 (2022)
Researchers have made crucial advances in understanding the pathogenesis and therapeutics of non-small cell lung cancer (NSCLC), improving our understanding of lung tumor biology and progression. Although the survival of NSCLC patients has improved d
Externí odkaz:
https://doaj.org/article/1ee4d9dd9cef4ed29c4709b04fa5838b
Autor:
Ying Chen, Jiali Li, Meng Zhang, Wei Yang, Wenqi Qin, Qinzhou Zheng, Yanhui Chu, Yan Wu, Dan Wu, Xiaohuan Yuan
Publikováno v:
Nutrients, Vol 14, Iss 11, p 2358 (2022)
We investigated the effect of an 11β-HSD1 inhibitor (H8) on hepatic steatosis and its mechanism of action. Although H8, a curcumin derivative, has been shown to alleviate insulin resistance, its effect on non-alcoholic fatty liver disease (NAFLD) re
Externí odkaz:
https://doaj.org/article/1eef3092375640d3a0f8812a8004c5f9