Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Xiaohua Yan"'
Autor:
Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Viruses, as opportunistic intracellular parasites, hijack the cellular machinery of host cells to support their survival and propagation. Numerous viral proteins are subjected to host-mediated post-translational modifications. Here, we demon
Externí odkaz:
https://doaj.org/article/e3e9e519f6b84b0e8f7d6e0867082a16
Autor:
Cheng Zhang, Zhihua Li, Kaiheng Hu, Yifei Ren, Haoran Zhang, Yuankang Zhao, Wenjing Wei, Shuo Tu, Xiaohua Yan
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Due to the therapeutic resistance of endocrine therapy and the limited efficacy of immune checkpoint inhibitors in estrogen receptor (ER)-positive breast cancer (BRCA), there is an urgent need to develop novel prognostic markers and understand the re
Externí odkaz:
https://doaj.org/article/e74a94d3f023474b8ce8449011171fc2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/46a599d064c44f8781b9bf8c8c87e245
Autor:
Zhenghong Lin, Xiaohua Yan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/3edf6f54bdf846e69a49dbbcbee1645b
Autor:
Charles P. Couturier, Shamini Ayyadhury, Phuong U. Le, Javad Nadaf, Jean Monlong, Gabriele Riva, Redouane Allache, Salma Baig, Xiaohua Yan, Mathieu Bourgey, Changseok Lee, Yu Chang David Wang, V. Wee Yong, Marie-Christine Guiot, Hamed Najafabadi, Bratislav Misic, Jack Antel, Guillaume Bourque, Jiannis Ragoussis, Kevin Petrecca
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Glioblastoma is thought to arise from neural stem cells. Here, to investigate this, the authors use single-cell RNA-sequencing to compare glioblastoma to the fetal human brain, and find a similarity between glial progenitor cells and a subpopulation
Externí odkaz:
https://doaj.org/article/b6efd45faa5f47efaab210dc9f398a89
Autor:
Ling Dong, Le Yu, Hui Li, Lei Shi, Zhong Luo, Huakan Zhao, Zhaojian Liu, Guobing Yin, Xiaohua Yan, Zhenghong Lin
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101351- (2020)
Summary: Ubiquitin specific protease 39 (USP39), an ortholog of Sad1p in yeast, is essential for spliceosome assembly during pre-mRNA splicing in human. Although it is known that USP39 is upregulated and plays an oncogenic role in hepatocellular carc
Externí odkaz:
https://doaj.org/article/2f361c8bfbac4c7d867ee35d43852352
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1143 (2021)
The overexpression of adenosine triphosphate (ATP)-binding cassette (ABC) subfamily B member 1 (ABCB1; P-glycoprotein; MDR1) in some types of cancer cells is one of the mechanisms responsible for the development of multidrug resistance (MDR), which l
Externí odkaz:
https://doaj.org/article/6984c543d5da43309544b9c70f221ab4
Autor:
Zhengkui Zhang, Yao Fan, Feng Xie, Hang Zhou, Ke Jin, Li Shao, Wenhao Shi, Pengfei Fang, Bing Yang, Hans van Dam, Peter ten Dijke, Xiaofeng Zheng, Xiaohua Yan, Junling Jia, Min Zheng, Jin Jin, Chen Ding, Sheng Ye, Fangfang Zhou, Long Zhang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
The activation of TGF-β signaling has been implicated in cancer metastasis. Here, the authors show that OTUD1 suppresses metastasis by antagonizing the TGF-β pathway via the deubiquitination of SMAD7, and its loss correlates with poor prognosis in
Externí odkaz:
https://doaj.org/article/c9f4c20d0b034062b275d5bddb7b2a17
Autor:
Charles P. Couturier, Shamini Ayyadhury, Phuong U. Le, Javad Nadaf, Jean Monlong, Gabriele Riva, Redouane Allache, Salma Baig, Xiaohua Yan, Mathieu Bourgey, Changseok Lee, Yu Chang David Wang, V. Wee Yong, Marie-Christine Guiot, Hamed Najafabadi, Bratislav Misic, Jack Antel, Guillaume Bourque, Jiannis Ragoussis, Kevin Petrecca
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/fbeb1d92ca714ed7b32e3bd99e2974f7
Publikováno v:
Cells, Vol 8, Iss 10, p 1235 (2019)
Primary liver cancer is one of the leading causes for cancer-related death worldwide. Transforming growth factor beta (TGF-β) is a pleiotropic cytokine that signals through membrane receptors and intracellular Smad proteins, which enter the nucleus
Externí odkaz:
https://doaj.org/article/98a487eebdba4ee99daa93196b6b595d