Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Xiaohua S. Huang"'
Autor:
Alicia Regueiro-Ren, Jacob J. Swidorski, Zheng Liu, Yan Chen, Ny Sin, Sing-Yuen Sit, Jie Chen, Brian L. Venables, Juliang Zhu, Beata Nowicka-Sans, Tricia Protack, Zeyu Lin, Brian Terry, Himadri Samanta, Sharon Zhang, Zhufang Li, John Easter, Brett R. Beno, Vinod Arora, Xiaohua S. Huang, Sandhya Rahematpura, Dawn D. Parker, Roy Haskell, Kenneth S. Santone, Mark I. Cockett, Mark Krystal, Nicholas A. Meanwell, Susan Jenkins, Umesh Hanumegowda, Ira B. Dicker
Publikováno v:
Journal of Medicinal Chemistry. 61:7289-7313
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c3666e9905493812ef4d0ec28c2e176
https://doi.org/10.1021/acs.jmedchem.8b00854
https://doi.org/10.1021/acs.jmedchem.8b00854
Autor:
Sing-Yuen Sit, Ny Sin, Umesh Hanumegowda, Dawn D. Parker, Zheng Liu, Alicia Regueiro-Ren, Xiaohua S. Huang, Brian Lee Venables, Brian Terry, Brett R. Beno, Sharon Zhang, Ira B. Dicker, Roy Haskell, Jacob Swidorski, Zhufang Li, Mark I. Cockett, Beata Nowicka-Sans, Zeyu Lin, Nicholas A. Meanwell, Tricia Protack, Sandhya Rahematpura, Juliang Zhu, Susan Jenkins, Himadri Samanta, Mark Krystal, Yan Chen, Kenneth S. Santone, Jie Chen
Publikováno v:
ACS Medicinal Chemistry Letters. 7:568-572
HIV-1 maturation inhibition (MI) has been clinically validated as an approach to the control of HIV-1 infection. However, identifying an MI with both broad polymorphic spectrum coverage and good oral exposure has been challenging. Herein, we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c6472d1d93201556f25ce37013cceb
https://doi.org/10.1021/acsmedchemlett.6b00010
https://doi.org/10.1021/acsmedchemlett.6b00010
Autor:
Alicia, Regueiro-Ren, Jacob J, Swidorski, Zheng, Liu, Yan, Chen, Ny, Sin, Sing-Yuen, Sit, Jie, Chen, Brian L, Venables, Juliang, Zhu, Beata, Nowicka-Sans, Tricia, Protack, Zeyu, Lin, Brian, Terry, Himadri, Samanta, Sharon, Zhang, Zhufang, Li, John, Easter, Brett R, Beno, Vinod, Arora, Xiaohua S, Huang, Sandhya, Rahematpura, Dawn D, Parker, Roy, Haskell, Kenneth S, Santone, Mark I, Cockett, Mark, Krystal, Nicholas A, Meanwell, Susan, Jenkins, Umesh, Hanumegowda, Ira B, Dicker
Publikováno v:
Journal of medicinal chemistry. 61(16)
GSK3532795, formerly known as BMS-955176 (1), is a potent, orally active, second-generation HIV-1 maturation inhibitor (MI) that advanced through phase IIb clinical trials. The careful design, selection, and evaluation of substituents appended to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec69348335bb02844efe70a17d779260
https://pubmed.ncbi.nlm.nih.gov/30067361
https://pubmed.ncbi.nlm.nih.gov/30067361