Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Xiaohua Mao"'
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-15 (2021)
Abstract ABIN-1, also called TNIP1, is an ubiquitin-binding protein that serves an important role in suppressing RIPK1-independent apoptosis, necroptosis, and NF-κB activation. However, the involvement of ABIN-1 in the regulation of RIPK1-dependent
Externí odkaz:
https://doaj.org/article/98a85561cbee4548b47f62e977420574
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
MALAT1-associated small cytoplasmic RNA (mascRNA) is a highly conserved transfer RNA–like (tRNA-like) noncoding RNA whose function remains largely unknown. We show here that this small RNA molecule played a role in the stringent control of TLR-medi
Externí odkaz:
https://doaj.org/article/f2b7dde0213c4d8d871cee0b80d8ec07
Publikováno v:
Molecular immunology. 154
mascRNA (MALAT1-associated small cytoplasmic RNA) is a tRNA-like cytoplasmic small noncoding RNA whose function remains elusive. We previously revealed that this small RNA negatively regulates TLR4/2-triggered proinflammatory response while positivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865a4e823bb89bf69c9248520563d5f0
https://pubmed.ncbi.nlm.nih.gov/36603304
https://pubmed.ncbi.nlm.nih.gov/36603304
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
ABIN-1, also called TNIP1, is an ubiquitin-binding protein that serves an important role in suppressing RIPK1-independent apoptosis, necroptosis, and NF-κB activation. However, the involvement of ABIN-1 in the regulation of RIPK1-dependent apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5984efcea0ebb89231d033b3388753e5
https://doaj.org/article/98a85561cbee4548b47f62e977420574
https://doaj.org/article/98a85561cbee4548b47f62e977420574
Publikováno v:
Biochemical and biophysical research communications. 611
Macrophages play a crucial role in the pathogenesis of rheumatoid arthritis (RA) and have been considered as a therapeutic target of this disease. Here we show that mascRNA, a tRNA-like cytoplasmic small noncoding RNA, promoted RIPK1-dependent apopto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4054f087f79b3f6e1b24e381dbee512d
https://pubmed.ncbi.nlm.nih.gov/35489201
https://pubmed.ncbi.nlm.nih.gov/35489201
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78619 (2013)
The role of interleukin (IL)-15 in the pathogenesis of rheumatoid arthritis (RA) is well established; however, systemic knockdown of IL-15 receptor (IL-15R) for reduction in inflammation at local sites has not been demonstrated. In this study, the th
Externí odkaz:
https://doaj.org/article/6ee6bb9a1b1343c28dfd4da917892ef6
Autor:
Xiaowei He, Yankai Xia, Xian Sun, Xinru Wang, Xiang Liu, Junwei Tang, Weibing Tang, Pin Wang, Zechao Wen, Kun Zhou, Xiaohua Mao, Minjian Chen, Bo Hang, Xuejiang Guo, Rongli Sun, Wei Lv, Richard A. White, Weiyue Hu, Fengli Liu, Hongxing Li
Publikováno v:
Free radical biologymedicine. 164
The etiology and pathogenesis of Hirschsprung's disease (HSCR) remain largely unknown. We examined colon tissues from three independent populations with a combined analysis of metabolomics, transcriptomics and proteomics to understand HSCR pathogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4877d87343133a65f12b679a9c2188c5
https://pubmed.ncbi.nlm.nih.gov/33465467
https://pubmed.ncbi.nlm.nih.gov/33465467
Publikováno v:
Immunology. 150:379-388
Summary The nuclear factor-κB (NF-κB) family of transcription factors play an essential role for the regulation of inflammatory responses, immune function and malignant transformation. Aberrant activity of this signalling pathway may lead to inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061d060b9f9d5bf17b3b924524df735d
https://doi.org/10.1111/imm.12698
https://doi.org/10.1111/imm.12698
Publikováno v:
Journal of visualized experiments : JoVE. (144)
Because of their critical role in regulating immune responses, macrophages have continuously been the subject of intensive research and represent a promising therapeutic target in many disorders, such as autoimmune diseases, atherosclerosis, and canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8436ff130e572dbd01b4b2d40e4ed382
https://pubmed.ncbi.nlm.nih.gov/30799850
https://pubmed.ncbi.nlm.nih.gov/30799850
Publikováno v:
Journal of Visualized Experiments.
Because of their critical role in regulating immune responses, macrophages have continuously been the subject of intensive research and represent a promising therapeutic target in many disorders, such as autoimmune diseases, atherosclerosis, and canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672fcaa7170af1f3407c13b722dc7bd1
https://doi.org/10.3791/58660
https://doi.org/10.3791/58660