Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xiaohao Yao"'
Autor:
Qingzhong Ren, Chuan-Chie Chang, Hui-Min Chen, Tzumin Lee, Rosa Linda Miyares, Xiaohao Yao, Ling-Yu Liu
Publikováno v:
Development.
Gene targeting is an incredibly valuable technique. Sometimes however, it can also be extremely challenging for various intrinsic reasons (e.g. low target accessibility or nature/extent of gene modification). To bypass these barriers, we designed a t
Autor:
Hui-Min, Chen, Xiaohao, Yao, Qingzhong, Ren, Chuan-Chie, Chang, Ling-Yu, Liu, Rosa Linda, Miyares, Tzumin, Lee
Publikováno v:
Development (Cambridge, England). 147(11)
Gene targeting is an incredibly valuable technique. Sometimes, however, it can also be extremely challenging for various intrinsic reasons (e.g. low target accessibility or nature/extent of gene modification). To bypass these barriers, we designed a
The efficiency of gene targeting can vary drastically. Even utilizing CRISPR/Cas9 does not ensure rapid, successful gene targeting. InDrosophila, we previously established Golic+ to augment gene-targeting productivity simply through fly pushing. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee540b14a6f8730470c24de1efab1ebe
https://doi.org/10.1101/681874
https://doi.org/10.1101/681874
Autor:
Yi Fu, Jianqing Zhao, Yanchao Yuan, Zhu Yaming, Shumei Liu, Alvianto Wirasaputra, Xiaohao Yao
Publikováno v:
Macromolecular Materials and Engineering. 301:982-991
Autor:
Tzumin Lee, Ching-Po Yang, Luke P. Lee, Ken Sugino, Ling-Yu Liu, Xiaohao Yao, Zhiyong Liu, Chi-Cheng Fu
Publikováno v:
Science. 350:317-320
Changes over time build neuronal diversity Although neural progenitors can keep generating new neurons, they can generate different neurons as the organism develops. Two different sections of the Drosophila brain, the mushroom bodies and the antennal
Publikováno v:
Genetics. 199:683-694
Ends-out gene targeting allows seamless replacement of endogenous genes with engineered DNA fragments by homologous recombination, thus creating designer “genes” in the endogenous locus. Conventional gene targeting in Drosophila involves targetin
Autor:
Dannel McCollum, Xiaohao Yao, Lan Xu, Michael P. Czech, Qi Li, Satoshi Kaneko, Xiaochu Chen, Laura V. Danai, Sebastian Mana-Capelli, Junhao Mao, Jennifer L. Cotton, Alla Amcheslavsky, Jin Jiang, Y. Tony Ip, Shuangxi Li, Rachel J. Roth Flach, Yingchao Nie
Publikováno v:
Developmental Cell. 31:291-304
Summary Similar to the mammalian intestine, the Drosophila adult midgut has resident stem cells that support growth and regeneration. How the niche regulates intestinal stem cell activity in both mammals and flies is not well understood. Here, we sho
Autor:
Hui-Min Chen, Xiaohao Yao, Qingzhong Ren, Chuan-Chie Chang, Ling-Yu Liu, Miyares, Rosa Linda, Lee, Tzumin
Publikováno v:
Development (09501991); Jun2020, Vol. 147 Issue 11, p1-9, 9p
Autor:
Xiaohao Yao, Y. Tony Ip, Ken-ichi Kariya, Junhao Mao, Lan Xu, Satoshi Kaneko, Xiaochu Chen, Theodore G. Wright, Peiyuan Lu, Mihir Rajurkar
Publikováno v:
Proceedings of the National Academy of Sciences. 108:11127-11132
The level of TGF-β/bone morphogenetic protein (BMP) signaling through Smad is tightly regulated to ensure proper embryonic patterning and homeostasis. Here we show that Smad activation by TGF-β/BMP is blocked by a highly conserved phosphorylation e
Publikováno v:
The Journal of biological chemistry. 283(33)
Trafficking of Smad proteins between the cytoplasm and nucleus is a critical component of transforming growth factor beta (TGF-beta) signal transduction. Smad4 translocates into the nucleus either in response to TGF-beta stimulation or when its nucle