Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Xiaoguang Margaret Liu"'
Autor:
Kai Chen, Seulhee Kim, Siying Yang, Tanvi Varadkar, Zhuoxin Zora Zhou, Jiashuai Zhang, Lufang Zhou, Xiaoguang Margaret Liu
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-15 (2024)
Abstract Recombinant adeno-associated virus (rAAV) has been developed as a safe and effective gene delivery vehicle to treat rare genetic diseases. This study aimed to establish a novel biomanufacturing process to achieve high production and purifica
Externí odkaz:
https://doaj.org/article/6ecc60b34bb940a7bab86ccd77f2127b
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: MitoView 633, a far-red fluorescent dye, exhibits the ability to accumulate within mitochondria in a membrane potential-dependent manner, as described by the Nernst equation. This characteristic renders it a promising candidate for bioe
Externí odkaz:
https://doaj.org/article/cb864b4bf9564be2b003091c30f840cf
Autor:
Yingnan Si, Ya Zhang, Jia-Shiung Guan, Hanh Giai Ngo, Angela Totoro, Ajeet Pal Singh, Kai Chen, Yuanxin Xu, Eddy S. Yang, Lufang Zhou, Runhua Liu, Xiaoguang (Margaret) Liu
Publikováno v:
Vaccines, Vol 9, Iss 8, p 882 (2021)
Triple-negative breast cancers (TNBCs) are frequently recurrent due to the development of drug resistance post chemotherapy. Both the existing literature and our study found that surface receptor CD47 (cluster of differentiation 47) was upregulated i
Externí odkaz:
https://doaj.org/article/350f5db6b6644dd2bf70d684a275c610
Publikováno v:
Frontiers in Physiology; 2023, p1-11, 11p
Autor:
Jin He, Seulhee Kim, Jia-Shiung Guan, Jianyi Jay Zhang, Xiaoguang Margaret Liu, Min Xie, Kai Chen, Yawen Tang, Lufang Zhou, Patrick Ernst
Publikováno v:
Pflugers Arch
Ca(2+) cycling plays a critical role in regulating cardiomyocyte (CM) function under both physiological and pathological conditions. Mitochondria have been implicated in Ca(2+) handling in adult cardiomyocytes (ACMs). However, little is known about t
Autor:
Lufang Zhou, Jia-Shiung Guan, Seulhee Kim, Xiaoguang Margaret Liu, Yingnan Si, Kai Chen, Eddy S. Yang, Yuanxin Xu
Publikováno v:
Engineering in Life Sciences
Triple‐negative breast cancers (TNBCs) are highly aggressive, metastatic and recurrent. Cytotoxic chemotherapies with limited clinical benefits and severe side effects are the standard therapeutic strategies, but, to date, there is no efficacious t
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071623282
Methods in Molecular Biology ISBN: 9781071623282
While optogenetic approaches have been widely used for remote control of cell membrane excitability and intracellular signaling pathways, their application in mitochondrial study has been limited, largely due to the challenge of effectively and speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef60448c0105c9bff90d0b55e65a8d81
https://europepmc.org/articles/PMC10210090/
https://europepmc.org/articles/PMC10210090/
Autor:
Lufang Zhou, Ajeet Pal Singh, Jia-Shiung Guan, Yuanxin Xu, Kai Chen, Hanh Giai Ngo, Eddy S. Yang, Qing Wang, Yingnan Si, Ya Zhang, Xiaoguang Margaret Liu
Publikováno v:
Cancers
Cancers, Vol 13, Iss 3749, p 3749 (2021)
Volume 13
Issue 15
Cancers, Vol 13, Iss 3749, p 3749 (2021)
Volume 13
Issue 15
Triple-negative breast cancers (TNBCs) are highly aggressive and recurrent. Standard cytotoxic chemotherapies are currently the main treatment options, but their clinical efficacies are limited and patients usually suffer from severe side effects. Th
Autor:
Asher Kahn-Krell, Danielle Pretorius, Jianfa Ou, Vladimir G. Fast, Silvio Litovsky, Joel Berry, Xiaoguang (Margaret) Liu, Jianyi Zhang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology
Human induced-pluripotent stem cells (hiPSCs) can be efficiently differentiated into cardiomyocytes (hiPSC-CMs) via the GiWi method, which uses small-molecule inhibitors of glycogen synthase kinase (GSK) and tankyrase to first activate and then suppr
Autor:
Patrick Ernst, Kai Chen, Jia-Shiung Guan, Ya Zhang, Yingnan Si, Seulhee Kim, Jianfa Ou, Lufang Zhou, Xiaoguang Margaret Liu, Xiaosi Han
Publikováno v:
Pharmaceuticals, Vol 14, Iss 427, p 427 (2021)
Pharmaceuticals
Volume 14
Issue 5
Pharmaceuticals
Volume 14
Issue 5
Meningiomas are primary tumors of the central nervous system with high recurrence. It has been reported that somatostatin receptor 2 (SSTR2) is highly expressed in most meningiomas, but there is no effective targeted therapy approved to control menin