Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Xiaofan Ding"'
Autor:
Xiaofan Ding, Mengxue Sun, Fusheng Guo, Xinmin Qian, Haoyu Yuan, Wenjiao Lou, Qixuan Wang, Xiaoguang Lei, Wenwen Zeng
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract New adjuvants that trigger cellular immune responses are urgently needed for the effective development of cancer and virus vaccines. Motivated by recent discoveries that show activation of type I interferon (IFN‐I) signaling boosts T cell
Externí odkaz:
https://doaj.org/article/532ff1c86fea48dfbacc917149cbeff3
Autor:
Stephanie Andaluz, Bojin Zhao, Siddharth Sinha, Philip Naderev Panuringan Lagniton, Diogo Alpuim Costa, Xiaofan Ding, Miguel Brito, San Ming Wang
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Admixture occurs between different ethnic human populations. The global colonization in recent centuries by Europeans led to the most significant admixture in human history. While admixture may enhance genetic diversity for better
Externí odkaz:
https://doaj.org/article/422599836d4f4210b48d84ee321e20ee
Autor:
Bojin Zhao, Jiaheng Li, Siddharth Sinha, Zixin Qin, Si Hoi Kou, Fengxia Xiao, Huijun Lei, Tianhui Chen, Wenming Cao, Xiaofan Ding, San Ming Wang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Genome stability is maintained by the DNA damage repair (DDR) system composed of multiple DNA repair pathways of hundreds of genes. Germline pathogenic variation (PV) in DDR genes damages function of the affected DDR genes, leadin
Externí odkaz:
https://doaj.org/article/9dbb202443294deeae552bed05a49163
Publikováno v:
Fundamental Research, Vol 4, Iss 2, Pp 201-205 (2024)
The pancreas exerts endocrine and exocrine functions in energy balance. The neural innervation and immune milieu are both crucial in supporting pancreatic homeostasis. The neuronal network connects the pancreas with the central nervous system (CNS) a
Externí odkaz:
https://doaj.org/article/25775d2bdd63467da322335e8fb03ae0
Autor:
Ryan Tsz‐Hei Tse, Christine Yim‐Ping Wong, Xiaofan Ding, Carol Ka‐Lo Cheng, Chit Chow, Ronald Cheong‐Kin Chan, Joshua Hoi‐Yan Ng, Victor Wai‐Lun Tang, Peter Ka‐Fung Chiu, Jeremy Yuen‐Chun Teoh, Nathalie Wong, Ka‐Fai To, Chi‐Fai Ng
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Introduction Kidney cancer is a common urological malignancy worldwide with an increasing incidence in recent years. Among all subtypes, renal cell carcinoma (RCC) represents the most predominant malignancy in kidney. Clinicians faced a majo
Externí odkaz:
https://doaj.org/article/8568ecb3f89e4e14bb1fd30b5680afa0
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionThe DNA damage repair (DDR) system in human genome is pivotal in maintaining genomic integrity. Pathogenic variation (PV) in DDR genes impairs their function, leading to genome instability and increased susceptibility to diseases, especia
Externí odkaz:
https://doaj.org/article/17426feaf18e430a9e58944f98618497
Autor:
Bonan Chen, Wai Nok Chan, Fuda Xie, Chun Wai Mui, Xiaoli Liu, Alvin H. K. Cheung, Raymond W. M. Lung, Chit Chow, Zhenhua Zhang, Canbin Fang, Peiyao Yu, Shihua Shi, Shikun Zhou, Guoming Chen, Zhangding Wang, Shouyu Wang, Xiaofan Ding, Bing Huang, Li Liang, Yujuan Dong, Chi Chun Wong, William K. K. Wu, Alfred S. L. Cheng, Nathalie Wong, Jun Yu, Kwok Wai Lo, Gary M. K. Tse, Wei Kang, Ka Fai To
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Background Cancer‐associated fibroblasts (CAFs), integral to the tumour microenvironment, are pivotal in cancer progression, exhibiting either pro‐tumourigenic or anti‐tumourigenic functions. Their inherent phenotypic and functional di
Externí odkaz:
https://doaj.org/article/9cd923a1d35b477fa1d0c64190bf7e15
Autor:
Shumin Wang, Zhenghao Guo, Xiaofan Ding, Linling Li, Zhongyou Jin, Chengcai Zhang, Shouping Liu, Yan Zhou, Gongduan Fan
Publikováno v:
Water, Vol 15, Iss 11, p 1991 (2023)
The littering of nitrogen into water bodies has led to several adverse effects on the environment. “Nitrification-denitrification” is still a prevalent method for removing nitrogen from water bodies, which demands high energy consumption and comp
Externí odkaz:
https://doaj.org/article/df4c5a59675642a4ba698c314892bc71
Autor:
Lei Liu, Tianyu Tao, Shihua Liu, Xia Yang, Xuwei Chen, Jiaer Liang, Ruohui Hong, Wenting Wang, Yi Yang, Xiaoyi Li, Youhong Zhang, Quanfeng Li, Shujun Liang, Haocheng Yu, Yun Wu, Xinyu Guo, Yan Lai, Xiaofan Ding, Hongyu Guan, Jueheng Wu, Xun Zhu, Jie Yuan, Jun Li, Shicheng Su, Mengfeng Li, Xiuyu Cai, Junchao Cai, Han Tian
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Activated Notch signalling promotes cancer metastasis and stemness. Here the authors show that Notch1 activates transcription of DNA replication factor RCF4 and that RCF4 binds and stabilises Notch1 intracellular domain (NICD1) to promote cancer meta
Externí odkaz:
https://doaj.org/article/d91f2bc20dee437894291254ef20f4fc
Autor:
Ryan Tsz-Hei Tse, Xiaofan Ding, Christine Yim-Ping Wong, Carol Ka-Lo Cheng, Peter Ka-Fung Chiu, Chi-Fai Ng
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 5926 (2022)
Spermidine/spermine N1-acetyltransferase (SSAT) functions as a critical enzyme in maintaining the homeostasis of polyamines, including spermine, spermidine, and putrescine, in mammalian cells. SSAT is a catalytic enzyme that indirectly regulates cell
Externí odkaz:
https://doaj.org/article/3c113793286e4b35b6abba52e13595b1