Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Xiaofan, Lai"'
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronically progressive fibrotic pulmonary disease characterized by an uncertain etiology, a poor prognosis, and a paucity of efficacious treatment options. Dexmedetomidine (Dex), an anesth
Externí odkaz:
https://doaj.org/article/2eed3ffe556c45db94fd2ecd2f41c3ab
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThere is still a lack of specific indicators to diagnose idiopathic pulmonary fibrosis (IPF). And the role of immune responses in IPF is elusive. In this study, we aimed to identify hub genes for diagnosing IPF and to explore the immune mic
Externí odkaz:
https://doaj.org/article/3edd6bd9a6aa438aa58d6169c831b9e1
Autor:
Senyu Yao, Xiaoyue Wei, Wenrui Deng, Boyan Wang, Jianye Cai, Yinong Huang, Xiaofan Lai, Yuan Qiu, Yi Wang, Yuanjun Guan, Jiancheng Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The regulatory mechanisms contributing to male reproductive ageing are unknown. Here, the authors show that Nestin-dependent mito-ER contacts (MERCs) regulate stem Leydig cell (SLC) senescence and provide insights into SLCs-targeting therapies.
Externí odkaz:
https://doaj.org/article/2845439343764e1fba6f73eab2348679
Autor:
Xiaofan Lai, Shaojie Huang, Sijia Lin, Lvya Pu, Yaqing Wang, Yingying Lin, Wenqi Huang, Zhongxing Wang
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive deadly fibrotic lung disease with high prevalence and mortality worldwide. The therapeutic potential of mesenchymal stem cells (MSCs) in pulmonary fibrosis may be at
Externí odkaz:
https://doaj.org/article/9ff9973e39834b47bca22bd363c85f0b
Autor:
Xiaofan Lai, Shaojie Huang, Sijia Lin, Lvya Pu, Yaqing Wang, Yingying Lin, Wenqi Huang, Zhongxing Wang
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/34fe16b15c034302b7c9524629275e95
Autor:
Boyan Wang, Yi Wang, Hainan Chen, Senyu Yao, Xiaofan Lai, Yuan Qiu, Jianye Cai, Yinong Huang, Xiaoyue Wei, Yuanjun Guan, Tao Wang, Jiancheng Wang, Andy Peng Xiang
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Background Cancer cachexia is a wasting syndrome that is quite common in terminal-stage cancer patients. Cancer-related anemia is one of the main features of cancer cachexia and mostly results in a poor prognosis. The disadvantages of the cu
Externí odkaz:
https://doaj.org/article/be482fd51d0c493ba40c226677da0c70
Autor:
DuBreuil, Daniel M.1,2, Xiaofan Lai1,3, Kevin Zhu1, Chahyadinata, Gracesenia1, Perner, Caroline4,5, Chiang, Brenda M.1, Battenber, Ashley1, Sokol, Caroline L4,6, Wainger, Brian J.1,6,7 brian.wainger@mgh.harvard.edu
Publikováno v:
Molecular Pain. Jan-Dec2023, Vol. 19, p1-13. 13p.
Autor:
Jiancheng Wang, Qiying Lu, Jianye Cai, Yi Wang, Xiaofan Lai, Yuan Qiu, Yinong Huang, Qiong Ke, Yanan Zhang, Yuanjun Guan, Haoxiang Wu, Yuanyuan Wang, Xin Liu, Yue Shi, Kang Zhang, Maosheng Wang, Andy Peng Xiang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Loss of Nestin sensitizes non-small cell lung carcinoma (NSCLC) to oxidative stress. Here, the authors report a feedback loop between Nestin and Nrf2 wherein Nestin competes with Nrf2 for Keap1 binding, preventing Nrf2 degradation, and show the Nesti
Externí odkaz:
https://doaj.org/article/b1b00c42536b4061b50abe0984df2505
Autor:
Yinong Huang, Jiancheng Wang, Xiaofan Lai, Yuan Qiu, Jianye Cai, Yuanchen Ma, Yilin Liu, Wei Qiu, Zhengqi Lu, Andy Peng Xiang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/ba20a6499c434bec819b9f4d02086453
Autor:
Daniel M. DuBreuil, Brenda M. Chiang, Kevin Zhu, Xiaofan Lai, Patrick Flynn, Yechiam Sapir, Brian J. Wainger
Publikováno v:
Cell Reports: Methods, Vol 1, Iss 1, Pp 100004- (2021)
Summary: High-throughput physiological assays lose single-cell resolution, precluding subtype-specific analyses of activation mechanism and drug effects. We demonstrate APPOINT (automated physiological phenotyping of individual neuronal types), a phy
Externí odkaz:
https://doaj.org/article/6a413c7ff9ff41f2a46b981a60dd4654