Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Xiaoduo Xie"'
Autor:
Canrong Li, Yuguo Yi, Yingyi Ouyang, Fengzhi Chen, Chuxin Lu, Shujun Peng, Yifan Wang, Xinyu Chen, Xiao Yan, Haolun Xu, Shuiming Li, Lin Feng, Xiaoduo Xie
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Background Mammalian or mechanistic target of rapamycin complex 1 (mTORC1) is an effective therapeutic target for diseases such as cancer, diabetes, aging, and neurodegeneration. However, an efficient tool for monitoring mTORC1 inhibition in
Externí odkaz:
https://doaj.org/article/28beb7d2842e4e32a2b2faa5864a439e
Autor:
Ruihua Wang, Ying Sun, Bo-Hua Kuang, Xiao Yan, Jinju Lei, Yu-Xin Lin, Jinxiu Tian, Yating Li, Xiaoduo Xie, Tao Chen, Hui Zhang, Yi-Xin Zeng, Jincun Zhao, Lin Feng
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTReplicating SARS-CoV-2 has been shown to degrade HLA class I on target cells to evade the cytotoxic T-cell (CTL) response. HLA-I downregulation can be sensed by NK cells to unleash killer cell immunoglobulin-like receptor (KIR)-mediated self-
Externí odkaz:
https://doaj.org/article/21dd99f7d5204c5981f5b07eda6a616e
Autor:
Liwei Xiao, Jing Liu, Zongchao Sun, Yujing Yin, Yan Mao, Dengqiu Xu, Lin Liu, Zhisheng Xu, Qiqi Guo, Chenyun Ding, Wanping Sun, Likun Yang, Zheng Zhou, Danxia Zhou, Tingting Fu, Wenjing Zhou, Yuangang Zhu, Xiao-Wei Chen, John Zhong Li, Shuai Chen, Xiaoduo Xie, Zhenji Gan
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009488 (2021)
Mitochondria are essential for maintaining skeletal muscle metabolic homeostasis during adaptive response to a myriad of physiologic or pathophysiological stresses. The mechanisms by which mitochondrial function and contractile fiber type are concord
Externí odkaz:
https://doaj.org/article/3b1a00c5bdac44c2a91bbf246ff541a3
Autor:
Xiangpeng Sheng, Qing You, Hongnian Zhu, ZeNan Chang, Qingrun Li, Haifeng Wang, Chen Wang, Hongyan Wang, Lijian Hui, Chongtao Du, Xiaoduo Xie, Rong Zeng, Anning Lin, Dongfang Shi, Kangcheng Ruan, Jinghua Yan, George Fu Gao, Feng Shao, Ronggui Hu
Publikováno v:
PLoS Pathogens, Vol 13, Iss 7, p e1006534 (2017)
As a major diarrheagenic human pathogen, enterohemorrhagic Escherichia coli (EHEC) produce attaching and effacing (A/E) lesions, characterized by the formation of actin pedestals, on mammalian cells. A bacterial T3SS effector NleL from EHEC O157:H7 w
Externí odkaz:
https://doaj.org/article/dfbfdb5e196c46948796e08f4ebfc316
Autor:
Canrong Li, Yingyi Ouyang, Chuxin Lu, Fengzhi Chen, Yuguo Yi, Shujun Peng, Yifan Wang, Xinyu Chen, Xiao Yan, Shuiming Li, Lin Feng, Xiaoduo Xie
SUMMARYMammalian or mechanistic target of rapamycin complex 1 (mTORC1) is a clinically effective therapeutic target for diseases such as cancer, diabetes, aging, and neurodegeneration, yet an efficient tool to monitor mTORC1 inhibition in living cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b70454c0b31d295bbe3d68181b7069f
https://doi.org/10.1101/2023.05.19.541400
https://doi.org/10.1101/2023.05.19.541400
Autor:
Yan Chen, Zhenzhen Wang, Yi Pan, Zhiqiang Ling, Yixuan Zhang, Zheng Wang, Zhigang Li, Xiaoduo Xie, Yuhui Jiang
Raf kinase trapping to Golgi (RKTG) is a potential tumor suppressor gene due to its negative roles in regulating Ras/Raf/MEK/ERK (extracellular signal–regulated kinase) pathway and GPCR (G protein–coupled receptor) Gβγ subunit signaling. Intere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70e40f33bf8ffd8f04e8ec2784aa155
https://doi.org/10.1158/0008-5472.c.6502854.v1
https://doi.org/10.1158/0008-5472.c.6502854.v1
Autor:
Yan Chen, Zhenzhen Wang, Yi Pan, Zhiqiang Ling, Yixuan Zhang, Zheng Wang, Zhigang Li, Xiaoduo Xie, Yuhui Jiang
Supplementary Methods, Figures 1-12 from Functional Cooperation of RKTG with p53 in Tumorigenesis and Epithelial–Mesenchymal Transition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1286c55e9099b9310f8dc1e51cedd307
https://doi.org/10.1158/0008-5472.22390170.v1
https://doi.org/10.1158/0008-5472.22390170.v1
Publikováno v:
Journal of oncology. 2022
Despite mounting evidence linking pyroptotic cell death to tumor growth, the clinical significance and disease mechanism of pyroptosis in cancer remain uncertain. In this study, we established a unique gene signature (π signature) that can be used a
Autor:
Qinrun Li, Ivan Dikic, Jiao Yang, Juan Du, Yongning He, Xuemin Zhang, Xiaoduo Xie, Hai Rao, Masaaki Komatsu, Byung-Hoon Lee, Ronggui Hu, Qin Xia, Daniel Finley, Daming Gao, Tao Zhang, Qing You, Jian Hou, Hongyan Wang, Wen Han, Tianrang Li, Hong Peng, Ying Huang, Lijian Hui, Guangyi Li, Rong Zeng
Publikováno v:
Cell Research. 27:657-674
Alterations in cellular ubiquitin (Ub) homeostasis, known as Ub stress, feature and affect cellular responses in multiple conditions, yet the underlying mechanisms are incompletely understood. Here we report that autophagy receptor p62/sequestosome-1
Autor:
John Zhong Li, Dengqiu Xu, Yuangang Zhu, Likun Yang, Yan Mao, Qiqi Guo, Zheng Zhou, Zhisheng Xu, Tingting Fu, Shuai Chen, Chenyun Ding, Zhenji Gan, Xiaowei Chen, Zongchao Sun, Wanping Sun, Yujing Yin, Wenjing Zhou, Liwei Xiao, Danxia Zhou, Jing Liu, Lin Liu, Xiaoduo Xie
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009488 (2021)
PLoS Genetics
PLoS Genetics
Mitochondria are essential for maintaining skeletal muscle metabolic homeostasis during adaptive response to a myriad of physiologic or pathophysiological stresses. The mechanisms by which mitochondrial function and contractile fiber type are concord