Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Xiaodi Yu"'
Autor:
Mark J. G. Bakkers, Tina Ritschel, Machteld Tiemessen, Jacobus Dijkman, Angelo A. Zuffianò, Xiaodi Yu, Daan van Overveld, Lam Le, Richard Voorzaat, Marlies M. van Haaren, Martijn de Man, Sem Tamara, Leslie van der Fits, Roland Zahn, Jarek Juraszek, Johannes P. M. Langedijk
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The prefusion conformation of human metapneumovirus fusion protein (hMPV Pre-F) is critical for eliciting the most potent neutralizing antibodies and is the preferred immunogen for an efficacious vaccine against hMPV respiratory infections.
Externí odkaz:
https://doaj.org/article/7253577e83f04ebd9e3caa7f032e9986
Autor:
Xiaodi Yu, Rosalie E. Matico, Robyn Miller, Dhruv Chauhan, Bertrand Van Schoubroeck, Karolien Grauwen, Javier Suarez, Beth Pietrak, Nandan Haloi, Yanting Yin, Gary John Tresadern, Laura Perez-Benito, Erik Lindahl, Astrid Bottelbergs, Daniel Oehlrich, Nina Van Opdenbosch, Sujata Sharma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The NACHT-, leucine-rich-repeat-, and pyrin domain-containing protein 3 (NLRP3) is a critical intracellular inflammasome sensor and an important clinical target against inflammation-driven human diseases. Recent studies have elucidated its t
Externí odkaz:
https://doaj.org/article/7f229443efb44bc9b6f041484b3699ef
Autor:
Xiaodi Yu, Pravien Abeywickrema, Brecht Bonneux, Ishani Behera, Brandon Anson, Edgar Jacoby, Amy Fung, Suraj Adhikary, Anusarka Bhaumik, Rodrigo J. Carbajo, Suzanne De Bruyn, Robyn Miller, Aaron Patrick, Quyen Pham, Madison Piassek, Nick Verheyen, Afzaal Shareef, Priscila Sutto-Ortiz, Nina Ysebaert, Herman Van Vlijmen, Tim H. M. Jonckers, Florence Herschke, Jason S. McLellan, Etienne Decroly, Rachel Fearns, Sandrine Grosse, Dirk Roymans, Sujata Sharma, Peter Rigaux, Zhinan Jin
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract The respiratory syncytial virus polymerase complex, consisting of the polymerase (L) and phosphoprotein (P), catalyzes nucleotide polymerization, cap addition, and cap methylation via the RNA dependent RNA polymerase, capping, and Methyltran
Externí odkaz:
https://doaj.org/article/155faab50b5b48fe954bff5b07e1b8ac
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18955- (2023)
Background: Vascular mild cognitive impairment (VMCI) is a common impairment caused by vascular factors. VMCI often occurs after stroke, and it is the main clinical manifestation of long-term disability. Many patients are treated with acupuncture in
Externí odkaz:
https://doaj.org/article/17226e8bb9fb4c7f9568a758046dedf8
Autor:
Xiaodi Yu, Jarek Juraszek, Lucy Rutten, Mark J G Bakkers, Sven Blokland, Jelle M Melchers, Niels J F van den Broek, Annemiek Y W Verwilligen, Pravien Abeywickrema, Johan Vingerhoets, Jean-Marc Neefs, Shah A Mohamed Bakhash, Pavitra Roychoudhury, Alex Greninger, Sujata Sharma, Johannes P M Langedijk
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011308 (2023)
The global spread of the SARS-CoV-2 virus has resulted in emergence of lineages which impact the effectiveness of immunotherapies and vaccines that are based on the early Wuhan isolate. All currently approved vaccines employ the spike protein S, as i
Externí odkaz:
https://doaj.org/article/0be9269368074520a2eea45098a564ec
Autor:
Tsehai A.J. Grell, Mark Mason, Aaron A. Thompson, Jose Carlos Gómez-Tamayo, Daniel Riley, Michelle V. Wagner, Ruth Steele, Rodrigo F. Ortiz-Meoz, Jay Wadia, Paul L. Shaffer, Gary Tresadern, Sujata Sharma, Xiaodi Yu
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12392- (2022)
Malic enzymes (ME1, ME2, and ME3) are involved in cellular energy regulation, redox homeostasis, and biosynthetic processes, through the production of pyruvate and reducing agent NAD(P)H. Recent studies have implicated the third and least well-charac
Externí odkaz:
https://doaj.org/article/0f71dae03abd4550a60deb71f7723386
Autor:
Nicholas G. Fox, Xiaodi Yu, Xidong Feng, Henry J. Bailey, Alain Martelli, Joseph F. Nabhan, Claire Strain-Damerell, Christine Bulawa, Wyatt W. Yue, Seungil Han
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
The iron-sulfur cluster (ISC) assembly complex is activated by frataxin (FXN) and Friedreich’s ataxia is caused by FXN deficiency. Here the authors present the 3.2 Å resolution cryo-EM structure of the human frataxin bound ISC complex and discuss
Externí odkaz:
https://doaj.org/article/8abcf6459af9457bb7545657bbc6ed8d
Publikováno v:
Viruses, Vol 14, Iss 2, p 414 (2022)
Various adenoviruses are being used as viral vectors for the generation of vaccines against chronic and emerging diseases (e.g., AIDS, COVID-19). Here, we report the improved capsid structure for one of these vectors, human adenovirus D26 (HAdV-D26),
Externí odkaz:
https://doaj.org/article/8eab7e75d5bf4922b0c247682e3fd303
Autor:
Xiaodi Yu, Jiang-Tao Li, Zhijie Qu, Ian U Roederer, Joel N Bregman, Xiaohui Fan, Taotao Fang, Sean D Johnson, Feige Wang, Jinyi Yang
Publikováno v:
Monthly Notices of the Royal Astronomical Society. 518:1975-1984
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71ec68d4450f56ac5b688719d817db9e
https://doi.org/10.1093/mnras/stac3054
https://doi.org/10.1093/mnras/stac3054
Autor:
Dawei Li, Hao Lu, Ya-Nan Chen, Xueqing Ma, Huarui Zhang, Hang Wang, Xiaodi Yu, Xiaoyun Xu, Zhe Zhang, Xinjun Xu, Yahui Liu, Zaifei Ma, Andong Zhang, Zhishan Bo
Publikováno v:
Chemistry of Materials. 34:8840-8848
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0e6edae22994c643f27764defee6d5a
https://doi.org/10.1021/acs.chemmater.2c02146
https://doi.org/10.1021/acs.chemmater.2c02146