Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Xiaodan Zhong"'
Autor:
Lei Dai, Yu Chen, Jinhua Wu, Zhen He, Yueqi Zhang, Wenjun Zhang, Yang Xie, Hesong Zeng, Xiaodan Zhong
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary disease characterized by complement dependent and proinflammatory activation of macrophages. However, effective treatment for complement activation in PAH is lackin
Externí odkaz:
https://doaj.org/article/95b66862e600499a90b97aa76e801548
Autor:
Yujiao Zhang, Marie Vandestienne, Jean-Rémi Lavillegrand, Jeremie Joffre, Icia Santos-Zas, Aonghus Lavelle, Xiaodan Zhong, Wilfried Le Goff, Maryse Guérin, Rida Al-Rifai, Ludivine Laurans, Patrick Bruneval, Coralie Guérin, Marc Diedisheim, Melanie Migaud, Anne Puel, Fanny Lanternier, Jean-Laurent Casanova, Clément Cochain, Alma Zernecke, Antoine-Emmanuel Saliba, Michal Mokry, Jean-Sebastien Silvestre, Alain Tedgui, Ziad Mallat, Soraya Taleb, Olivia Lenoir, Cécile Vindis, Stéphane M. Camus, Harry Sokol, Hafid Ait-Oufella
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Caspase recruitment-domain containing protein 9 (CARD9) is a key signaling pathway in macrophages but its role in atherosclerosis is still poorly understood. Global deletion of Card9 in Apoe -/- mice as well as hematopoietic deletion in Ldlr
Externí odkaz:
https://doaj.org/article/b269b498eb06438890385181c12ba8bb
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background Studies have proven that the same family of non-coding RNAs (ncRNAs) have similar functions, so predicting the ncRNAs family is helpful to the research of ncRNAs functions. The existing calculation methods mainly fall into two cat
Externí odkaz:
https://doaj.org/article/aa0c9d459483433eaab22ac3a25fc5ee
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Studies have shown that RNA secondary structure, a planar structure formed by paired bases, plays diverse vital roles in fundamental life activities and complex diseases. RNA secondary structure profile can record whether each bas
Externí odkaz:
https://doaj.org/article/9829816e14db412d8c366738dfbc208f
Autor:
Xiaodan Zhong, Songling Zhang, Yutong Zhang, Zongmiao Jiang, Yanan Li, Jian Chang, Junqi Niu, Ying Shi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Neuroblastoma (NB) is the most common solid tumor apart from central nervous system malignancies in children aged 0–14 years, and the outcomes of high-risk patients are dismal. High mobility group box 3 (HMGB3) plays an oncogenic role in many cance
Externí odkaz:
https://doaj.org/article/ac6f809af9ed480482f6d8408066c047
Autor:
Xuemei Yang, Jialing Sun, Bin Wen, Yu Wang, Mingjia Zhang, Weicong Chen, Wenting Zhao, Chunyu He, Xiaodan Zhong, Yang Liu, Tong Li, Haitao Sun, Songqi He
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Tumor-infiltrating CD8+T lymphocytes are mostly associated with a favorable prognosis in numerous cancers, including hepatocellular carcinoma (HCC). Biejiajian Pill (BJJP) is a common type of traditional Chinese medicine that is widely used in the tr
Externí odkaz:
https://doaj.org/article/859dd14da93849368281d126f25fce42
Autor:
Xiaodan Zhong, Tao Wang, Yang Xie, Mengwen Wang, Wenjun Zhang, Lei Dai, Jinsheng Lai, Xiang Nie, Xingwei He, Thati Madhusudhan, Hesong Zeng, Hongjie Wang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Aims: The pathogenesis of diabetic cardiomyopathy (DCM) is complex and the detailed mechanism remains unclear. Coagulation protease activated Protein C (aPC) has been reported to have a protective effect in diabetic microvascular disease. Here, we in
Externí odkaz:
https://doaj.org/article/2b5c8fd2f7be485cb4d0b8368771eac2
Autor:
Lei Dai, Yang Xie, Wenjun Zhang, Xiaodan Zhong, Mengwen Wang, Hongcheng Jiang, Zhen He, Xiaolei Liu, Hesong Zeng, Hongjie Wang
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundDiabetic cardiomyopathy (DbCM) is characterized by initial impairment of left ventricular relaxation followed by contractile dysfunction. Despite intensive research, the exact mechanism remains so far unsolved.MethodsWe constructed weighted
Externí odkaz:
https://doaj.org/article/5b4e28105d344dedb1eede70a689a1e7
Autor:
Mingjia Zhang, Yi Zhang, Haitao Sun, Hui Ni, Jialing Sun, Xuemei Yang, Weicong Chen, Wenting Zhao, Xiaodan Zhong, Chunyu He, Haiqing Ao, Songqi He
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Objective: Corticosterone causes significant neurotoxicity in primary hippocampal neurons which is associated with depression. Dysfunctional autophagy is implicated in cognitive impairment and depressive-like behavior. The traditional Chinese medicin
Externí odkaz:
https://doaj.org/article/6e7927ca4e1049d7a549f5b9aed27202
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe prognostic value of immune-related genes and lncRNAs in neuroblastoma has not been elucidated, especially in subgroups with different outcomes. This study aimed to explore immune-related prognostic signatures.Materials and MethodsImmune
Externí odkaz:
https://doaj.org/article/434cb30f79d54599ab06ff3ea53380c6