Development of a Two-Dimensional Liquid Chromatography Online Deproteinization Method for Determining Paclitaxel-Related Substances in a Paclitaxel Injection (Albumin-Bound)

Autor: Jing Yao, Xuejia Zhao, Yifei Jiang, Limin Zuo, Xiaodan Qiu, Xiaofang Lian, Huiyi Liu, Qingying Jia, Huimin Sun, Guangzhi Shan

Publikováno v: Separations, Vol 11, Iss 8, p 223 (2024)

To determine the paclitaxel-related substances in a paclitaxel injection (albumin-bound), it is necessary to remove human blood albumin from the sample via solid-phase extraction and subsequently perform high-performance liquid chromatography analysi

Externí odkaz: https://doaj.org/article/4bc197dc5734456b92c537bb9e3f8140

Baseline Characteristics of Frailty and Disease Stage in Older People Living With CKD

Autor: Antony, Deanna Nisha, Arenson, Ricky, Bale, Owen, Braat, Sabine, Lobo Brites, Benilda Maria, Broers, Sally, Buckle, Graham, Bukkapatnam, Sreenath, Cerni, Joanne, Chan, Doris, Collins, Michael G., Elms, Amanda, Fanning, John, Fischer, Karen, Flavell, Adam, Flicker, Leon, Furst, Chloe, Gordon, Emily H., Govindarajulu, Sridevi, Grainer, Natalie, Green, Stella Jean, Green, Suetonia C., Guha, Chandana, Hand, Samantha, Nur Hidayati, Leny Dwi, Irvine, Rachael, Ismail, Ibrahim, Jesudason, Shilpanjali, Kan, George, Kang, Ya-Yu, Kelly, Leonie, Kennedy, Debbie, Khatry, Khadija, Khelgi, Vinod, Kokoszka, Shannon, Krishnan, Anoushka, Lane, Heather, Leary, Diana, Lees, Andrea, Long, Claire, Makris, Angela, Marquez, Khalilah Katherine, Maxwell, Amanda, McGrath, Amanda, McIntyre, David, Murie, Penelope, Murphy, Karina, Chróinín, Danielle Ní, Peel, Nancye M., Xiaodan Qiu, Stephanie Polley, Rapisardi, Madeleine, Roberts, Matthew A., Roger, Simon D., Saxena, Shailly, Sen, Shaundeep, Strivens, Edward, Varghese, Julie, Waite, Louise M., Walker, Robert, Wong, Daniel, Yates, Paul Andrew, Yip, Belinda, Zaharia, Andreea, Logan, Benignus, Pascoe, Elaine M., Viecelli, Andrea K., Johnson, David W., Comans, Tracy, Hawley, Carmel M., Hickey, Laura E., Janda, Monika, Jaure, Allison, Kalaw, Emarene, Kiriwandeniya, Charani, Matsuyama, Misa, Mihala, Gabor, Nguyen, Kim-Huong, Pole, Jason D., Polkinghorne, Kevan R., Pond, Dimity, Raj, Rajesh, Reidlinger, Donna M., Scholes-Robertson, Nicole, Valks, Andrea, Wong, Germaine, Hubbard, Ruth E.

Publikováno v: In Kidney International Reports January 2025 10(1):120-133

Blocking Effect of Demethylzeylasteral on the Interaction between Human ACE2 Protein and SARS-CoV-2 RBD Protein Discovered Using SPR Technology

Autor: Xiaodan Qiu, Yi-Tong Liu, Ting Zhao, Shuo Wu, Zhong-Hao Sun, Zhuorong Li, Zhiling Zhu, Guangzhi Shan

Publikováno v: Molecules, Vol 26, Iss 57, p 57 (2021)
Molecules
Volume 26
Issue 1

The novel coronavirus disease (2019-nCoV) has been affecting global health since the end of 2019, and there is no sign that the epidemic is abating. Targeting the interaction between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d00f19c41127d54cb953b2df8185e42
https://www.mdpi.com/1420-3049/26/1/57

Separation of chiral and achiral impurities in paroxetine hydrochloride in a single run using supercritical fluid chromatography with a polysaccharide stationary phase

Autor: Guangzhi Shan, Limin Zuo, Xun Ma, Ting Zhao, Yi-Tong Liu, Xiaodan Qiu

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 208:114458

Separating paroxetine hydrochloride and its impurities using conventional reversed-phase liquid chromatography (RPLC) is challenging due to their highly similar structures. In the present study, a rapid, simple, sensitive and environmentally friendly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbcbbbd06fc4c5df1386e2bffe3f9ba
https://doi.org/10.1016/j.jpba.2021.114458

Impurity profiling of Compound Amino Acid Injection (6AA) using ion-pair high performance liquid chromatography coupled with corona-charged aerosol detection and high resolution mass spectrometry

Autor: Limin Zuo, Xuejia Zhao, Guangzhi Shan, Xiaodan Qiu, Zhiling Zhu, Ting Zhao, Zhong-Hao Sun, Shengnan Sun, Shijie Xu, Jing Yao

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 201:114099

The complex industrial production process of amino acids (AAs) leads to the existence of a certain amount of impurities in Compound Amino Acid Injection (6AA). It is difficult to obtain its comprehensive and systematic impurity profile using conventi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12899e5a443950eace56dc65ec6d5e6c
https://doi.org/10.1016/j.jpba.2021.114099