Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Xiaocui He"'
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BackgroundCurrent reports on the prognostic and predictive value of hypoxia-inducible factor-1α (HIF-1α) in endometrial carcinoma are inconsistent. Therefore, we conducted this meta-analysis to precisely evaluate the association of HIF-1α expressi
Externí odkaz:
https://doaj.org/article/480490a2d7b14c438651d8d348e19ce3
Autor:
Robert Kammerer, Martin Mansfeld, Jana Hänske, Sophie Mißbach, Xiaocui He, Bernd Köllner, Susan Mouchantat, Wolfgang Zimmermann
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Expansions of gene families are predictive for ongoing genetic adaptation to environmental cues. We describe such an expansion of the carcinoembryonic antigen (CEA) gene family in certain bat families. Members of the CEA family in
Externí odkaz:
https://doaj.org/article/e1925070498d4e31b8628fe8a6499a07
Publikováno v:
Molecular and Cellular Biochemistry. 464:39-50
Ovarian cancer (OC) is the most lethal gynecologic malignancy and long non-coding RNAs (lncRNAs) have been acknowledged as important regulators in human OC. This study aimed to investigate the function and underlying mechanisms of LINC00504 in OC. Th
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The specific activation of B lymphocytes via the binding of antigen to their B cell antigen receptor (BCR) is of central importance for the establishment of humoral immunity and a successful vaccination. A better understanding of the ant
Autor:
Xiaocui He, Tomáš Korytář, Yaqing Zhu, Jiří Pikula, Hana Bandouchova, Jan Zukal, Bernd Köllner
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109795 (2014)
Bats are found to be the natural reservoirs for many emerging viruses. In most cases, severe clinical signs caused by such virus infections are normally not seen in bats. This indicates differences in the virus-host interactions and underlines the ne
Externí odkaz:
https://doaj.org/article/7a28d759a3724a20a6787513191ec67c
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76464 (2013)
The evolution of TLR-mediated innate immunity is a fundamental question in immunology. Here, we report the characterization and functional analysis of four TLR members in the lophotrochozoans Crassostreagigas (CgTLRs). All CgTLRs bear a conserved dom
Externí odkaz:
https://doaj.org/article/0244fd54c1e44eb2b90db0d1d4c5715a
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
BackgroundCurrent reports on the prognostic and predictive value of hypoxia-inducible factor-1α (HIF-1α) in endometrial carcinoma are inconsistent. Therefore, we conducted this meta-analysis to precisely evaluate the association of HIF-1α expressi
Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes
Autor:
Markus Köhler, Laura Hoenig, Anja E. Hauser, Kathrin Brenker, Ellen McAllister, Deniz Saltukoglu, Marieta Caganova, Huda Jumaa, Xiaocui He, Michael Reth, Ruth Leben, Klaus Rajewsky, Raluca A. Niesner, Julia Jellusova
Publikováno v:
Life Science Alliance
Immunoglobulins shape mitochondrial function by driving ER expansion, this form of metabolic control is independent of the role the immunoglobulins play as part of the antigen receptor on the cell surface.
The major function of B lymphocytes is
The major function of B lymphocytes is
Autor:
Jana Hänske, Robert Kammerer, Wolfgang Zimmermann, Bernd Köllner, Martin Mansfeld, Xiaocui He, Sophie Mißbach, Susan Mouchantat
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
BMC Genomics
BMC Genomics
Background Expansions of gene families are predictive for ongoing genetic adaptation to environmental cues. We describe such an expansion of the carcinoembryonic antigen (CEA) gene family in certain bat families. Members of the CEA family in humans a
Autor:
Xiaocui He, Michael Reth, Kathrin Kläsener, Palash Chandra Maity, Martin Becker, Peter J. Nielsen, Marco Cavallari, Jianying Yang, Joseena M Iype
Publikováno v:
The EMBO Journal
Expression of the B‐cell antigen receptor (BCR) is essential not only for the development but also for the maintenance of mature B cells. Similarly, many B‐cell lymphomas, including Burkitt lymphoma (BL), require continuous BCR signaling for thei