Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Xiaocong Ye"'
Publikováno v:
Journal of Medicinal Chemistry. 50:2718-2731
A series of threo-1-aza-3 or 4-substituted-5-phenyl[4.4.0]decanes (quinolizidines), which were envisioned as restricted rotational analogues (RRAs) of methylphenidate (MP), was synthesized and tested for inhibitory potency against [(3)H]WIN35,428, [3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c81603111429fb1d99cd89bc9fdc91
https://doi.org/10.1021/jm061354p
https://doi.org/10.1021/jm061354p
Publikováno v:
European Journal of Medicinal Chemistry. 36:303-311
In order to make new analogs of the dopamine (DA) uptake inhibitor methylphenidate, a synthetic methodology based on the Blaise reaction was developed. The reaction between alpha-bromophenylacetic acid esters, zinc and alpha-cyano-omega-mesylates gav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e62fe8db6f1177ff3d7bceb207c7e61
https://doi.org/10.1016/s0223-5234(01)01230-2
https://doi.org/10.1016/s0223-5234(01)01230-2
Autor:
Rudolph A. Abramovitch, Xiaocong Ye
Publikováno v:
The Journal of Organic Chemistry. 64:5904-5912
The stereochemistry of 1-(3-benzyloxyphenyl)-2-(4-nitrophenyl)ethane has been studied. MMX calculations predicted, and 2D NOESY confirmed, that the bent conformation (global energy minimum) was such that six-membered ring formation, and not macrocycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baf8cdeaa0e695eb98cfe3b40176f41c
https://doi.org/10.1021/jo990362t
https://doi.org/10.1021/jo990362t
Autor:
Xiaocong Ye, Rudolph A. Abramovitch
Publikováno v:
ChemInform. 30
The stereochemistry of 1-(3-benzyloxyphenyl)-2-(4-nitrophenyl)ethane has been studied. MMX calculations predicted, and 2D NOESY confirmed, that the bent conformation (global energy minimum) was such that six-membered ring formation, and not macrocycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d32337104440a98f2d9f608b01e3d34f
https://doi.org/10.1002/chin.199946054
https://doi.org/10.1002/chin.199946054
Autor:
Qing Shi, Howard M. Deutsch, Milind Misra, Xiaocong Ye, Carol A. Venanzi, Zhanzhu Liu, Margaret M. Schweri, Wei Bu, Ewa Gruszecka-Kowalik
Publikováno v:
Bioorganicmedicinal chemistry. 18(20)
Complementary two-dimensional (2D) and three-dimensional (3D) Quantitative Structure–Activity Relationship (QSAR) techniques were used to derive a preliminary model for the dopamine transporter (DAT) binding affinity of 80 racemic threo-methylpheni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333782933edd836f716cacdb17bab99a
https://pubmed.ncbi.nlm.nih.gov/20846865
https://pubmed.ncbi.nlm.nih.gov/20846865
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::857468a992c7712e7c762843a34a9aec
https://doi.org/10.1002/chin.200143152
https://doi.org/10.1002/chin.200143152
Publikováno v:
The Journal of organic chemistry. 65(2)
1-(4-Nitrophenyl)-7-phenylthioheptane (1) and -9-phenylthiononane (2) have been synthesized and their conformations studied in solution and in the solid state. MMX calculations suggest that the global energy minimum structures are bent in the gas pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba8f3b38c26777efec980b8ec838c2c
https://pubmed.ncbi.nlm.nih.gov/10813940
https://pubmed.ncbi.nlm.nih.gov/10813940
Publikováno v:
Journal of Medicinal Chemistry; May2007, Vol. 50 Issue 11, p2718-2731, 14p
Autor:
Abramovitch, Rudolph A., Xiaocong, Ye
Publikováno v:
Journal of Organic Chemistry; 1/28/2000, Vol. 65 Issue 2, p343, 9p, 14 Diagrams
Autor:
Abramovitch, Rudolph A., Xiaocong Ye
Publikováno v:
Journal of Organic Chemistry; 08/06/99, Vol. 64 Issue 16, p5904, 9p, 38 Diagrams