Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Xiaochun Dong"'
Publikováno v:
Chengshi guidao jiaotong yanjiu, Vol 27, Iss 1, Pp 138-143 (2024)
[Objective] The current design calculation methods for platform width suffer from issues such as low passenger flow prediction accuracy, broad range of passenger flow density parameter values, unclear selection criteria, and a lack of quantifiable ba
Externí odkaz:
https://doaj.org/article/8612eea988094d34a64c79e7656b7818
Autor:
Xianzi Zheng, Zhezheng Fang, Weizi Huang, Jianping Qi, Xiaochun Dong, Weili Zhao, Wei Wu, Yi Lu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 10, Pp 3972-3985 (2022)
Due to the overwhelming percentage of poorly water-soluble drugs, pharmaceutical industry is in urgent need of efficient approaches for solubilization and permeability improvement. Salts consisting of lipophilic fatty acid anions and hydrophilic chol
Externí odkaz:
https://doaj.org/article/40b6de478f7742a7960f88c211c03a2e
Autor:
Yifan Cai, Xin Ji, Yunsen Zhang, Chang Liu, Zichen Zhang, Yongjiu Lv, Xiaochun Dong, Haisheng He, Jianping Qi, Yi Lu, Defang Ouyang, Weili Zhao, Wei Wu
Publikováno v:
Aggregate, Vol 4, Iss 2, Pp n/a-n/a (2023)
Abstract Environment‐responsive fluorophores with aggregation‐caused quenching (ACQ) properties have been applied to track nanocarriers with reduced artefacts caused by unbound or free fluorophores but suffer from incomplete fluorescence quenchin
Externí odkaz:
https://doaj.org/article/f534763aa3fa4cbfbe3a982104394c99
Autor:
Haisheng He, Chang Liu, Jiang Ming, Yongjiu Lv, Jianping Qi, Yi Lu, Xiaochun Dong, Weili Zhao, Wei Wu
Publikováno v:
Aggregate, Vol 3, Iss 5, Pp n/a-n/a (2022)
Abstract Probing the onset of micellization, or determining the critical micelle concentration (CMC), is of crucial importance while remains to be challenged by growing demand for extraordinary sensitivity and accuracy. Although fluorometry has attra
Externí odkaz:
https://doaj.org/article/f1eff243330448c3948ee2d5f17e226b
In vivo dissolution of poorly water-soluble drugs: Proof of concept based on fluorescence bioimaging
Autor:
Yinqian Yang, Yongjiu Lv, Chengying Shen, Tingting Shi, Haisheng He, Jianping Qi, Xiaochun Dong, Weili Zhao, Yi Lu, Wei Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 4, Pp 1056-1068 (2021)
In vitro‒in vivo correlation (IVIVC) of solid dosage forms should be established basically between in vitro and in vivo dissolution of active pharmaceutical ingredients. Nevertheless, in vivo dissolution profiles have never been accurately portraye
Externí odkaz:
https://doaj.org/article/b9d45f80cb5445a1a8fb1af80e2f041d
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 4, Pp 1010-1020 (2021)
Self-microemulsifying drug delivery systems (SMEDDSs) have recently returned to the limelight of academia and industry due to their enormous potential in oral delivery of biomacromolecules. However, information on gastrointestinal lipolysis and trans
Externí odkaz:
https://doaj.org/article/ee82a718d92b4171baef4ff26a9d23be
Autor:
Xiaoyan Li, Liru Guo, Caixia Liu, Yanhui Cheng, Mei Kong, Lei Yang, Zhichao Zhuang, Jia Liu, Ming Zou, Xiaochun Dong, Xu Su, Qing Gu
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1535-1545 (2019)
ABSTRACTInfluenza A virus infections occur in different species, causing mild to severe respiratory symptoms that lead to a heavy disease burden. Eurasian avian-like swine influenza A(H1N1) viruses (EAS-H1N1) are predominant in pigs and occasionally
Externí odkaz:
https://doaj.org/article/e6fc88b557444cdfb734076f1ee041a3
Autor:
Lin Li, Wenti Xu, Abram L. Wagner, Xiaochun Dong, Jieying Yin, Ying Zhang, Matthew L. Boulton
Publikováno v:
Journal of Infection and Public Health, Vol 12, Iss 1, Pp 70-76 (2019)
Background: Workplaces are a common location for infectious disease transmission among adults. To provide recommendations regarding appropriate health promotion programs, we evaluated the impact of three different interventions on factory workers. Me
Externí odkaz:
https://doaj.org/article/ff621f67a92c426cafbe0b70030ee226
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 8, Iss 1, Pp 97-105 (2018)
Biomimetic nanocarriers are emerging as efficient vehicles to facilitate dietary absorption of biomacromolecules. In this study, two vitamins, thiamine and niacin, are employed to decorate liposomes loaded with insulin, thus facilitating oral absorpt
Externí odkaz:
https://doaj.org/article/aafad66bb1624b888d7f033c0b2b61b0
Autor:
Mingfei Zhu, Hong Wang, Chenglin Wang, Yanfen Fang, Tong Zhu, Weili Zhao, Xiaochun Dong, Xiongwen Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Inhibition of aberrant Hedgehog (Hh) pathway had been proved to be a promising therapeutic intervention in cancers like basal cell carcinoma (BCC), medulloblastoma (MB), and so on. Two drugs (Vismodegib, Sonidegib) were approved to treat BCC and more
Externí odkaz:
https://doaj.org/article/94503f7f48fa464aafb2ee8e5f02fe7a