Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Xiaochuang Luo"'
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32834 (2012)
MicroRNAs (miRNAs) are a class of short RNAs that regulate gene expression through either translational repression or mRNA cleavage. miRNA-181a (miR-181a), one of the many miRNAs conserved among vertebrates, is differentially expressed in a variety o
Externí odkaz:
https://doaj.org/article/49b922f80131413e9eaf4f9a5eadbec4
Autor:
Xiaochuang Luo1 (AUTHOR), Jingyi Gu1 (AUTHOR), Rongxuan Zhu2 (AUTHOR), Maoxiao Feng1 (AUTHOR), Xuejiao Zhu1 (AUTHOR), Yumin Li1 (AUTHOR), Jia Fei1 (AUTHOR) efeijia@163.com
Publikováno v:
BMC Systems Biology. 2014, Vol. 8 Issue 1, p82-91. 10p. 5 Graphs.
Publikováno v:
Hematology. 18:334-340
The development of resistance to imatinib mesylate may partly depend on high bcr-abl expression levels or point mutation(s). Arsenic trioxide (ATO) has bcr-abl suppressing activity in vitro, without cross-resistance to imatinib. Meanwhile, bcr-abl al
Autor:
Zhao Yin, Xiaochuang Luo, Maoxiao Feng, Juhua Yang, Yumin Li, Li Tianfu, Chunming Gu, Jia Fei, Wang Ruirui
Publikováno v:
Oncotarget
BCR/ABL is a well-known activator of multiple signaling pathways. RalA, a Ras downstream signaling molecule and a small GTPase, plays an important role in Bcr-Abl-induced leukemogenesis but the exact mechanism remains elusive. Here, we show that RalA
Publikováno v:
Journal of drug targeting. 23(1)
Background: miR-155 acts as a ubiquitous oncogene in major classes of human cancers and is a potential target for therapeutic intervention. However, the role of miR-155 in multiple myeloma is poorly understood.Methods: To explore the role of miR-155
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3, p e32834 (2012)
PLoS ONE, Vol 7, Iss 3, p e32834 (2012)
MicroRNAs (miRNAs) are a class of short RNAs that regulate gene expression through either translational repression or mRNA cleavage. miRNA-181a (miR-181a), one of the many miRNAs conserved among vertebrates, is differentially expressed in a variety o
Publikováno v:
Cellular signalling. 24(6)
Chronic myelogenous leukemia (CML) results from the transformation of a primitive hematopoietic cell by the bcr-abl gene. RalA, one of the Ras superfamily of small GTPases, is a downstream molecule of bcr-abl fusion protein in ras signaling pathway,