Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Xiaochuan Hong"'
Autor:
Xinran Wang, Lu Lu, Xiaochuan Hong, Lingling Wu, Chao Yang, You Wang, Wenwen Li, Yuanqin Yang, Dongqing Cao, Wen Di, Liufu Deng
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113712- (2024)
Summary: Adoptive cell therapies are emerging forms of immunotherapy that reprogram T cells for enhanced antitumor responses. Although surface programmed cell death-ligand 1 (PD-L1)/programmed cell death protein 1 (PD-1) engagement inhibits antitumor
Externí odkaz:
https://doaj.org/article/c211f961db7e47afa0a8ede41e1bee65
Autor:
Lu Lu, Chao Yang, Xingyue Zhou, Lingling Wu, Xiaochuan Hong, Wenwen Li, Xinran Wang, Yuanqin Yang, Dongqing Cao, Ao Zhang, Wen Di, Liufu Deng
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113108- (2023)
Summary: Natural killer (NK) cells are cytotoxic innate lymphocytes that eradicate tumor cells. Inducing durable antitumor immune responses by NK cells represents a major priority of cancer immunotherapy. While cytosolic DNA sensing plays an essentia
Externí odkaz:
https://doaj.org/article/44425f5759c74c5aa177f82e54668fa4
Autor:
Lingling Wu, Yuanqin Yang, Dongqing Cao, Chao Yang, Meng Wu, Zhen Zhang, Xinran Wang, Youqiong Ye, Jinmei Li, Hui Xiao, Liufu Deng, Lu Lu, Xiangjiao Meng, Jinming Yu, Jingsi Jin, Jinke Cheng, Xiaochuan Hong, Wenwen Li
Publikováno v:
Science Advances
Description
ZBP1-MLKL necroptotic signaling bridges tumor cell damage to antitumor immune responses after radiation.
Necroptosis, a form of regulated necrosis, participates in tumor development and dying cell immunogenicity. However, it rem
ZBP1-MLKL necroptotic signaling bridges tumor cell damage to antitumor immune responses after radiation.
Necroptosis, a form of regulated necrosis, participates in tumor development and dying cell immunogenicity. However, it rem
Autor:
Chao, Yang, Jingsi, Jin, Yuanqin, Yang, Hongxiang, Sun, Lingling, Wu, Mingyi, Shen, Xiaochuan, Hong, Wenwen, Li, Lu, Lu, Dongqing, Cao, Xinran, Wang, Jing, Sun, Youqiong, Ye, Bing, Su, Liufu, Deng
Publikováno v:
Immunity. 55(7)
The incidence and mortality rates of many non-reproductive human cancers are generally higher in males than in females. However, the immunological mechanism underlying sexual differences in cancers remains elusive. Here, we demonstrated that sex-rela
Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity
Autor:
Chao Yang, Jingsi Jin, Yuanqin Yang, Hongxiang Sun, Lingling Wu, Mingyi Shen, Xiaochuan Hong, Wenwen Li, Lu Lu, Dongqing Cao, Xinran Wang, Jing Sun, Youqiong Ye, Bing Su, Liufu Deng
Publikováno v:
Immunity. 55:1268-1283.e9
Autor:
Chao Yang, Yuanqin Yang, Dongqing Cao, Xinran Wang, Fanlin Li, Xuanming Yang, Juanjuan Lu, Bing Su, Jinke Cheng, Meng Wu, Xiaochuan Hong, Jingsi Jin, Liufu Deng, Lingling Wu, Wen Di, Lu Lu, Wenwen Li
Publikováno v:
Science Translational Medicine. 12
Although cGAS-STING-mediated DNA sensing in tumor cells or phagocytes is central for launching antitumor immunity, the role of intrinsic cGAS-STING activation in T cells remains unknown. Here, we observed that peripheral blood CD8+ T cells from patie
Autor:
Wenwen, Li, Lu, Lu, Juanjuan, Lu, Xinran, Wang, Chao, Yang, Jingsi, Jin, Lingling, Wu, Xiaochuan, Hong, Fanlin, Li, Dongqing, Cao, Yuanqin, Yang, Meng, Wu, Bing, Su, Jinke, Cheng, Xuanming, Yang, Wen, Di, Liufu, Deng
Publikováno v:
Science translational medicine. 12(549)
Although cGAS-STING-mediated DNA sensing in tumor cells or phagocytes is central for launching antitumor immunity, the role of intrinsic cGAS-STING activation in T cells remains unknown. Here, we observed that peripheral blood CD8
Autor:
Yuanqin Yang1,2, Meng Wu3, Dongqing Cao1, Chao Yang1, Jingsi Jin1, Lingling Wu1, Xiaochuan Hong1, Wenwen Li1, Lu Lu1,2, Jinmei Li1, Xinran Wang4, Xiangjiao Meng3, Zhen Zhang5, Jinke Cheng6, Youqiong Ye1, Hui Xiao7, Jinming Yu3 sdyujinming@126.com, Liufu Deng1,2 dengliufu@sjtu.edu.cn
Publikováno v:
Science Advances. 10/8/2021, Vol. 7 Issue 41, p1-16. 16p.