Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Xiaochu Shi"'
Publikováno v:
Nature Immunology. 10:297-305
CRACC is a self-associating member of the signaling lymphocytic activation molecule family that is expressed on cells of the immune system, including natural killer cells and activated T cells. Here we examine the function and mechanism of action of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7616fdabaaa2908601977adaf463f74
https://doi.org/10.1038/ni.1693
https://doi.org/10.1038/ni.1693
Publikováno v:
Molecular and Cellular Biology. 26:5559-5568
SAP is an intracellular adaptor molecule composed almost exclusively of an SH2 domain. It is mutated in patients with X-linked lymphoproliferative disease, a human immunodeficiency. Several immune abnormalities were also identified in SAP-deficient m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b5e68525425b2ceeea9f19391007b6
https://doi.org/10.1128/mcb.00357-06
https://doi.org/10.1128/mcb.00357-06
Autor:
Quanxin Meng, Brendan B. Antiochos, Miriam C. Poirier, Xiaochu Shi, Dale M. Walker, Ofelia A. Olivero, Vernon E. Walker
Publikováno v:
Proceedings of the National Academy of Sciences. 97:12667-12671
Drug combinations that include nucleoside reverse transcriptase inhibitors (NRTIs) are remarkably effective in preventing maternal-viral transmission of HIV during pregnancy. However, there may be potential long-term risks for children exposed in ute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0f15220d0f7da98930aa883f5aa395
https://doi.org/10.1073/pnas.220203197
https://doi.org/10.1073/pnas.220203197
Publikováno v:
Mutagenesis. 15:405-410
Previous experiments in our research group showed that 3'-azido-3'-deoxythymidine (AZT) caused increased mutant frequencies (Mfs) at the X-linked hypoxanthine-guanine phosphoribosyltransferase (HPRT) and the autosomal thymidine kinase (TK) genes in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4407128a46c62e9cd71065e291ff0328
https://doi.org/10.1093/mutage/15.5.405
https://doi.org/10.1093/mutage/15.5.405
Autor:
Johan G. deBoer, J. Andrews, Xiaochu Shi, Thomas R. Skopek, Vernon E. Walker, Dale M. Walker, Hillary E. Sussman, Patricia B. Upton, Nancy J. Gorelick
Publikováno v:
Environmental and Molecular Mutagenesis. 34:167-181
The relative sensitivities and specificities of the endogenous Hprt gene and the lacI transgene as mutational targets were evaluated in splenic lymphocytes from male standard B6C3F1 mice (only Hprt assayed) and from lacI transgenic B6C3F1 mice treate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b85581e5148e1068cfa9747db4b527f3
https://doi.org/10.1002/(sici)1098-2280(1999)34:2/3<167::aid-em16>3.0.co
https://doi.org/10.1002/(sici)1098-2280(1999)34:2/3<167::aid-em16>3.0.co
Autor:
Ming-Chao Zhong, Dominique Davidson, Zhongjun Dong, André Veillette, Shaohua Zhang, Xiaochu Shi
SAP (also named SH2D1A) is an intracellular adaptor molecule expressed in T cells, natural killer (NK) cells, and some B cells. TheSAPgene is mutated in X-linked lymphoproliferative (XLP) disease, a human immunodeficiency characterized by a faulty im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f8a7ddb4296f45bd67820a9de3e638
https://europepmc.org/articles/PMC2234128/
https://europepmc.org/articles/PMC2234128/
Autor:
Xiaochu Shi, Riyan Chen, James E R Taylor, André Veillette, Luo Yin, Mario-Ernesto Cruz-Munoz, Shaohua Zhang, Romain Roncagalli, Sylvain Latour
Publikováno v:
Nature immunology. 6(10)
EAT-2 is an adaptor expressed in innate immune cells, including natural killer (NK) cells. It is closely related to the adaptor SAP, which regulates signaling lymphocyte activation molecule (SLAM)–related receptors by recruiting the kinase FynT to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b324b3afe927eba164abaffcdbf42a
https://pubmed.ncbi.nlm.nih.gov/16177799
https://pubmed.ncbi.nlm.nih.gov/16177799
Autor:
Marcin Bakinowski, Riyan Chen, André Veillette, Romain Roncagalli, Xiaochu Shi, Dominique Davidson, Sylvain Latour, Pamela L. Schwartzberg
Publikováno v:
Nature cell biology. 5(2)
SAP (or SH2D1A), an adaptor-like molecule expressed in immune cells, is composed almost exclusively of a Src homology 2 (SH2) domain. In humans, SAP is mutated and either absent or non-functional in X-linked lymphoproliferative (XLP) syndrome, a dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365e2f8eab8d58950b60831e889ce512
https://pubmed.ncbi.nlm.nih.gov/12545173
https://pubmed.ncbi.nlm.nih.gov/12545173
Autor:
Stephen A. Judice, Michael J Bauer, Vernon E Walker, Richard J. Albertini, Xiaochu Shi, Hillary E. Sussman
Publikováno v:
Environmental and molecular mutagenesis. 38(1)
Previous studies have compared age-related differences in total mutagenic burden in mice of differing age (preweanling, weanling, or young adult) after single intraperitoneal (i.p.) injections of ethylnitrosourea (ENU). The purpose of the present inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48fcef1aa79a2ecc9b245772c658981
https://pubmed.ncbi.nlm.nih.gov/11473385
https://pubmed.ncbi.nlm.nih.gov/11473385
Autor:
Quanxin Meng, Ting Su, Miriam C. Poirier, Ofelia A. Olivero, Xinxin Ding, Xiaochu Shi, Vernon E Walker
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 54(2)
3'-Azido-3'-deoxythymidine (AZT), a thymidine analogue widely used in the treatment of AIDS patients and for prevention of the onset of AIDS in HIV-seropositive individuals, causes tumors in mice exposed as adults or in utero. The purpose of this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc7a1a21269cb3201993b3a677abc1d
https://pubmed.ncbi.nlm.nih.gov/10774814
https://pubmed.ncbi.nlm.nih.gov/10774814