Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Xiaocheng Charlie Dong"'
Autor:
Lin Xu, Xinge Zhang, Yue Xin, Jie Ma, Chenyan Yang, Xi Zhang, Guoqing Hou, Xiaocheng Charlie Dong, Zhaoli Sun, Xiwen Xiong, Xuan Cao
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-11 (2021)
Abstract Alcohol-related liver disease (ALD), a condition caused by alcohol overconsumption, occurs in three stages of liver injury including steatosis, hepatitis, and cirrhosis. DEP domain-containing protein 5 (DEPDC5), a component of GAP activities
Externí odkaz:
https://doaj.org/article/ecec4c1d48184b1aa6e347417dfd630b
Autor:
Xiaocheng Charlie Dong
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Patatin-like phospholipase domain-containing protein 3 (PNPLA3) is a lipid droplet-associated protein that has been shown to have hydrolase activity toward triglycerides and retinyl esters. The first evidence of PNPLA3 being associated with fatty liv
Externí odkaz:
https://doaj.org/article/1cfcb7d6e1324770b95d71b1e779e16d
Autor:
Defeng Cai, Sarah E. Graham, Cristen J. Willer, Roger Pique-Regi, Zhipeng Liu, Xiaocheng Charlie Dong, Yang Zhang, Xiaokun Wang, Y. Eugene Chen, Wanqing Liu, Menghao Huang
Publikováno v:
J Hepatol
Background & Aims Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes (T2D) and obesity are epidemiologically correlated with each other but the causal inter-relationships between them remain incompletely understood. We aimed to explore the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32aaed7716166a3e0434ce04a3e4e53
https://doi.org/10.1016/j.jhep.2020.03.006
https://doi.org/10.1016/j.jhep.2020.03.006
Autor:
Menghao Huang, Suthat Liangpunsakul, Gaihong Wang, Jun Wan, Xiwen Xiong, Yang Zhang, Zhaoli Sun, Xinge Zhang, Xiaocheng Charlie Dong, Yue Xin, Sheng Liu, Ali Ahmadi, Hyeong-Geug Kim
Publikováno v:
J Hepatol
Background & Aims As a nicotinamide adenine dinucleotide-dependent deacetylase and a key epigenetic regulator, sirtuin 6 (SIRT6) has been implicated in the regulation of metabolism, DNA repair, and inflammation. However, the role of SIRT6 in alcohol-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105945a24feab5e49034f6e28bf8b6f8
https://doi.org/10.1016/j.jhep.2019.06.019
https://doi.org/10.1016/j.jhep.2019.06.019
Publikováno v:
Antioxid Redox Signal
Significance: Fatty liver disease is a major liver disorder in the modern societies. Comprehensive understanding of the pathophysiology and molecular mechanisms is essential for the prevention and treatment of the disease. Recent Advances: Remarkable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7540786dd3bd90ba38d8c5d8266e9f
https://pubmed.ncbi.nlm.nih.gov/33906425
https://pubmed.ncbi.nlm.nih.gov/33906425
Autor:
Chenyan Yang, Xuan Cao, Zhaoli Sun, Lin Xu, Xinge Zhang, Jie Ma, Yue Xin, Xiaocheng Charlie Dong, Xi Zhang, Guoqing Hou, Xiwen Xiong
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 7, Pp 1-11 (2021)
Cell Death and Disease, Vol 12, Iss 7, Pp 1-11 (2021)
Alcohol-related liver disease (ALD), a condition caused by alcohol overconsumption, occurs in three stages of liver injury including steatosis, hepatitis, and cirrhosis. DEP domain-containing protein 5 (DEPDC5), a component of GAP activities towards
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab8af5f299044963fcc4915eb0b31e2
https://pubmed.ncbi.nlm.nih.gov/34267188
https://pubmed.ncbi.nlm.nih.gov/34267188
Autor:
Wanqing Liu, Y. Eugene Chen, Yang Zhang, Roger Pique-Regi, Sarah E. Graham, Cristen J. Willer, Xiaocheng Charlie Dong, Zhipeng Liu
BackgroundNon-alcoholic fatty liver disease (NAFLD) is epidemiologically correlated with both type 2 diabetes (T2D) and obesity. However, the causal inter-relationships among the three diseases have not been completely investigated.AimWe aim to explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38005c41a40d862f7faafd68bf136943
Autor:
Chuanpeng Dong, Edward Dong, Yunlong Liu, Menghao Huang, Yunjian Liu, Xiaocheng Charlie Dong, Hyeong-Geug Kim, Suthat Liangpunsakul
Publikováno v:
Biochim Biophys Acta Mol Basis Dis
Sestrin 3 (Sesn3) belongs to a small protein family that has been implicated in multiple biological processes including anti-oxidative stress, anti-aging, cell signaling, and metabolic homeostasis. However, the role of Sesn3 in hepatocellular carcino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87f1ca97dbcf91e67865a29813b8923
https://pubmed.ncbi.nlm.nih.gov/31351129
https://pubmed.ncbi.nlm.nih.gov/31351129
Autor:
Xiaocheng Charlie Dong
Publikováno v:
Expert opinion on therapeutic targets. 19(8)
Sestrins (Sesn1/2/3) belong to a small protein family that has versatile biological functions. In addition to initially characterized oxidoreductase activity, sestrins also have oxidoreductase-independent functions, including activation of AMP-activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b890061a9ca4d7b58cf9bc56ff8db78
https://pubmed.ncbi.nlm.nih.gov/25944222
https://pubmed.ncbi.nlm.nih.gov/25944222