Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Xiaochang Zhang"'
Autor:
Xiaochang Zhang
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Pediatric neurological disorders are frequently devastating and present unmet needs for effective medicine. The successful treatment of spinal muscular atrophy with splice-switching antisense oligonucleotides (SSO) indicates a feasible path to target
Externí odkaz:
https://doaj.org/article/cd25d3966b8f4bccb3957936e641c3e3
Autor:
Chunxiao Xu, Jing Dong, Danru Liu, Jianwei Xu, Bingyin Zhang, Zilong Lu, Linhong Wang, Junli Tang, Xiaochang Zhang, Jie Ren, Xiaohui Yu, Rui Guo, Xiaolei Guo, Jing Wu, Jixiang Ma
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundExcessive sodium and low potassium intake are involved in the development of hypertension. Growing evidence showed that the sodium-to-potassium ratio (Na/K) was significantly associated with blood pressure (BP). However, studies on the dose
Externí odkaz:
https://doaj.org/article/9a77a910b0c04003a180b7f30a20185b
Publikováno v:
Zhongguo gonggong weisheng, Vol 39, Iss 9, Pp 1185-1190 (2023)
ObjectiveTo examine the implementation of diabetes health management project and its influence on knowledge awareness, health behavior, medication, and blood glucose control among the diabetes patients with the standardized management for the improve
Externí odkaz:
https://doaj.org/article/9571774814d145d8b2924df86bb76cfb
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract RNA-binding proteins (RBPs) are essential for gene regulation, but it remains a challenge to identify their RNA targets across cell types. Here we present PIE-Seq to investigate Protein-RNA Interaction with dual-deaminase Editing and Sequenc
Externí odkaz:
https://doaj.org/article/998b5f45e6c34b76ad670375956012e3
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113335- (2023)
Summary: Dysregulation of alternative splicing has been repeatedly associated with neurodevelopmental disorders, but the extent of cell-type-specific splicing in human neural development remains largely uncharted. Here, single-cell long-read sequenci
Externí odkaz:
https://doaj.org/article/dc72d4aca3a94f959b24712dd28855b4
Autor:
Elaine T. Lim, Yingleong Chan, Pepper Dawes, Xiaoge Guo, Serkan Erdin, Derek J. C. Tai, Songlei Liu, Julia M. Reichert, Mannix J. Burns, Ying Kai Chan, Jessica J. Chiang, Katharina Meyer, Xiaochang Zhang, Christopher A. Walsh, Bruce A. Yankner, Soumya Raychaudhuri, Joel N. Hirschhorn, James F. Gusella, Michael E. Talkowski, George M. Church
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Cerebral organoids can be used to gain insights into neuropsychiatric disorders. Here the authors carry out RNAseq characterization from organoids derived from donors with autism spectrum disorder to identify associated cell type specific driver gene
Externí odkaz:
https://doaj.org/article/95de5f4e0e584e9ba9efd47fbab020ce
Autor:
Limei Ying, Xiaochang Zhang, Nina Lu, Lei Zhao, Yanfang Nie, Guofen Wang, Sai Chen, Linglong Xu
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
Objective Several laboratory and imaging assays are required to diagnose multiple myeloma (MM). Serum and urine immunofixation electrophoresis are two key assays to diagnose MM, while they have not been extensively utilized in Chinese hospitals. Seru
Externí odkaz:
https://doaj.org/article/c46f843711f84432bb42fa7fa7f43d97
Autor:
Mingjie Ma, Honghui Wang, Jin Xu, Yongming Huang, Dongxing Yuan, Xiaochang Zhang, Qingyong Song
Publikováno v:
ACS Omega, Vol 5, Iss 49, Pp 31551-31558 (2020)
Externí odkaz:
https://doaj.org/article/764eefddceaf4cd18932a6eb33dfe794
Autor:
Jijing Shi, Jianglin Zhou, Xiaochang Zhang, Wei Hu, Jin-Fang Zhao, Shengqi Wang, Fu-Sheng Wang, Ji-Yuan Zhang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundMucosal-associated invariant T (MAIT) cells are considered to participate of the host immune response against acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection; however, single-cell transcriptomic profiling of MAI
Externí odkaz:
https://doaj.org/article/bea7897802e84706839bf277f2347a78
Autor:
Yuan Li, Xiao Hu, Feng J He, Graham A MacGregor, Puhong Zhang, Rong Luo, Zhaoxue Yin, Jixiang Ma, Xiaochang Zhang, Jinglei Wang
Publikováno v:
BMJ Open, Vol 10, Iss 5 (2020)
Introduction Salt intake in China is twice the upper limit recommended by the WHO, and nearly 80% of salt is added during cooking. This study will develop a package of salt reduction interventions targeting home cooks and evaluate its effectiveness a
Externí odkaz:
https://doaj.org/article/d57d791458924d4a96650b0fd7fab17a