Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Xiaocang, Cao"'
Autor:
Ying Wang, Jing Han, Guang Yang, Shuhui Zheng, Gaoshi Zhou, Xinjuan Liu, Xiaocang Cao, Guang Li, Bowen Zhang, Zhuo Xie, Li Li, Mudan Zhang, Xiaoling Li, Minhu Chen, Shenghong Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Mucus injury associated with goblet cell (GC) depletion constitutes an early event in inflammatory bowel disease (IBD). Using single-cell sequencing to detect critical events in mucus dysfunction, we discover that the Kazal-type serine prote
Externí odkaz:
https://doaj.org/article/f8bacd038b644f14a2b595b6ae7e4d0e
Autor:
Enze Fu, Meng Qian, Ningning He, Yilun Yin, Yue Liu, Zhibo Han, ZhongChao Han, Qiang Zhao, Xiaocang Cao, Zongjin Li
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract The management of dysfunctional intestinal epithelium by promoting mucosal healing and modulating the gut microbiota represents a novel therapeutic strategy for inflammatory bowel disease (IBD). As a convenient and well‐tolerated method of
Externí odkaz:
https://doaj.org/article/98aaf7c66cf64b979b4011562c6ea74d
Autor:
Jiahao Wu, He Huang, Lina Wang, Mengxue Gao, Shuxian Meng, Shaolan Zou, Yuanhang Feng, Zeling Feng, Zhixin Zhu, Xiaocang Cao, Bingzhi Li, Guangbo Kang
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTIntestinal microbiota dysbiosis and metabolic disruption are considered essential characteristics in inflammatory bowel disorders (IBD). Reasonable butyrate supplementation can help patients regulate intestinal flora structure and promote muc
Externí odkaz:
https://doaj.org/article/6c8e077e257f46bb8abe58a562dda82f
Autor:
Xiaotian Chu, Xuanfu Chen, Huimin Zhang, Yufang Wang, Hong Guo, Yan Chen, Xiaowei Liu, Zhenhua Zhu, Yao He, Xueli Ding, Qunying Wang, Changqing Zheng, Xiaocang Cao, Hong Yang, Jiaming Qian
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
ObjectiveTo investigate the association between dietary and some other environmental factors and the risk of inflammatory bowel diseases (IBD) in Chinese population.Materials and methodsA multicenter case-control study was conducted involving 11 hosp
Externí odkaz:
https://doaj.org/article/8bfb9934f0ae4259ad8748563a290a3f
Autor:
Yulin Ye, Limin Liu, Yang Jing, Shuangzhe Yao, Mo Yang, Xin Dai, Meiyu Piao, Xin Xu, Zelin Feng, Xiaoli Wang, Yifei Liu, Junming Miao, Xingjie Gao, Qingxiang Yu, Xiaocang Cao, Xiangxiang Pan
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 7, Pp 874-876 (2024)
Externí odkaz:
https://doaj.org/article/e0240469754546e9bf2f4c7a59e46486
Autor:
Limin Liu, Yulin Ye, Rui Lin, Tianyu Liu, Sinan Wang, Zelin Feng, Xiaoli Wang, Hailong Cao, Xin Chen, Junming Miao, Yifei Liu, Kui Jiang, Zhibo Han, Zongjin Li, Xiaocang Cao
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Ferroptosis is a newly discovered form of cell death that is featured in a wide range of diseases. Exosome therapy is a promising therapeutic option that has attracted much attention due to its low immunogenicity, low toxicity, and ability t
Externí odkaz:
https://doaj.org/article/473882418c114cca9cc6e9c7d8e78abe
Autor:
Jiewen Wang, Guangbo Kang, Huiying Lu, Ario deMarco, Haibin Yuan, Zelin Feng, Mengxue Gao, Xiaoli Wang, Huahong Wang, Xiaolan Zhang, Yuli Wang, Miao Zhang, Ping Wang, Yuanhang Feng, Zhanju Liu, Xiaocang Cao, He Huang
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Background Inflammatory bowel diseases (IBDs) pose significant challenges in terms of treatment non‐response, necessitating the development of novel therapeutic approaches. Although biological medicines that target TNF‐α (tumour necrosi
Externí odkaz:
https://doaj.org/article/fa072c420d474d83b860711a021c74f5
Autor:
Mengfan Zhang, Yang Jing, Wenze Xu, Xiaojing Shi, Wenguang Zhang, Pengfei Chen, Xiaocang Cao, Xinwei Han, Xuhua Duan, Jianzhuang Ren
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-17 (2023)
Abstract Hepatic stellate cell is one of the major nonparenchymal cell types in liver. It has been proved the hepatic stellate cells are activated upon liver injury and produce excessive extracellular matrix to induce liver fibrosis. Single-cell RNA
Externí odkaz:
https://doaj.org/article/81ceceb2cea842d8b30c9a0dc450227f
Autor:
Juan Du, Junlei Zhang, Lin Wang, Xun Wang, Yaxing Zhao, Jiaoying Lu, Tingmin Fan, Meng Niu, Jie Zhang, Fei Cheng, Jun Li, Qi Zhu, Daoqiang Zhang, Hao Pei, Guang Li, Xingguang Liang, He Huang, Xiaocang Cao, Xinjuan Liu, Wei Shao, Jianpeng Sheng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Ulcerative colitis is a chronic inflammatory bowel disorder with cellular heterogeneity. To understand the composition and spatial changes of the ulcerative colitis ecosystem, here we use imaging mass cytometry and single-cell RNA sequencing
Externí odkaz:
https://doaj.org/article/e3dcdf2b05c141f9b0e478721e87034b
Autor:
Zelin Feng, Guangbo Kang, Jiewen Wang, Xingjie Gao, Xiaoli Wang, Yulin Ye, Limin Liu, Jingwen Zhao, Xinjuan Liu, He Huang, Xiaocang Cao
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114174- (2023)
Emerging biologics and small-molecule drugs have changed the clinical status quo of inflammatory bowel disease (IBD). However, current treatments remain at a standstill in terms of response and remission in many cases. Accumulating evidence indicates
Externí odkaz:
https://doaj.org/article/a3c951a663524e24af06d631f5e45884