Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Xiaobin Mei"'
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
Diabetic nephropathy, as a severe microvascular complication of diabetes, manifests in four clinical types: classic, albuminuria regression, a rapid decline in kidney function (RDKF), and non-proteinuric or non-albuminuric DKD. Rapidly progressive di
Externí odkaz:
https://doaj.org/article/8e6a085f46aa4fc0bcb0e4655aa3e8ce
Autor:
Zhonglian Cao, Hui Zhao, Jiajun Fan, Yilan Shen, Lei Han, Guangjun Jing, Xian Zeng, Xin Jin, Zeguo Zhu, Qi Bian, Yanyang Nan, Xiaozhi Hu, Xiaobin Mei, Dianwen Ju, Ping Yang
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract The pathogenesis of diabetic kidney disease (DKD) is complicated. Current clinical treatments fail to achieve satisfactory efficacy in the prevention of DKD progression, it urgently needs novel and effective treatment for DKD. In this study,
Externí odkaz:
https://doaj.org/article/0de5f18b146b4cb391f39ab3c1f381b1
Autor:
Si Chen, Xiaoyan Ma, Xun Zhou, Yi Wang, WeiWei Liang, Liang Zheng, Xiujuan Zang, Xiaobin Mei, Yinghui Qi, Yan Jiang, Shanbao Zhang, Jinqing Li, Hui Chen, Yingfeng Shi, Yan Hu, Min Tao, Shougang Zhuang, Na Liu
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Background and aimProtein-energy wasting (PEW) is critically associated with the reduced quality of life and poor prognosis of hemodialysis patients. However, the diagnosis criteria of PEW are complex, characterized by difficulty in estimating dietar
Externí odkaz:
https://doaj.org/article/e078c9bf3a8245d8b63f690a334d3810
Autor:
Yilan Shen, Wei Chen, Lei Han, Qi Bian, Jiajun Fan, Zhonglian Cao, Xin Jin, Tao Ding, Zongshu Xian, Zhiyong Guo, Wei Zhang, Dianwen Ju, Xiaobin Mei
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 127-142 (2021)
Diabetic nephropathy (DN) is considered the primary causes of end-stage renal disease (ESRD) and is related to abnormal glycolipid metabolism, hemodynamic abnormalities, oxidative stress and chronic inflammation. Antagonism of vascular endothelial gr
Externí odkaz:
https://doaj.org/article/23d1b1f1b1e14c69acb4298e438526d9
Autor:
Xuyao Zhang, Yichen Wang, Jiajun Fan, Wei Chen, Jingyun Luan, Xiaobin Mei, Shaofei Wang, Yubin Li, Li Ye, Song Li, Wenzhi Tian, Kai Yin, Dianwen Ju
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Background Inhibitors targeting VEGF and VEGFR are commonly used in the clinic, but only a subset of patients could benefit from these inhibitors and the efficacy was limited by multiple relapse mechanisms. In this work, we aimed to investig
Externí odkaz:
https://doaj.org/article/ce87a851c9474d56ac93ac2110d12aaf
Autor:
Lei Han, Chenchen Shi, Xian Zeng, Lifeng Cen, Xiaobin Mei, Jiajun Fan, Dianwen Ju, Haiyan Zhu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Influenza A virus infection is usually associated with acute lung injury, which is typically characterized by tracheal mucosal barrier damage and an interleukin 17A (IL-17A)-mediated inflammatory response in lung tissues. Although targeting IL-17A ha
Externí odkaz:
https://doaj.org/article/f23b96bcf26a4c70a3313367c4c0b1ab
Autor:
Wei Chen, Yilan Shen, Jiajun Fan, Xian Zeng, Xuyao Zhang, Jingyun Luan, Yichen Wang, Jinghui Zhang, Si Fang, Xiaobin Mei, Zhen Zhao, Dianwen Ju
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 2, Pp n/a-n/a (2021)
Abstract Kidney damage initiates the deteriorating metabolic states in tubule cells that lead to the development of end‐stage renal disease (ESTD). Interleukin‐22 (IL‐22) is an effective therapeutic antidote for kidney injury via promoting kidn
Externí odkaz:
https://doaj.org/article/bf9b9a4e7c534c9b80aa0fe378121b0b
Publikováno v:
Cellular Physiology and Biochemistry, Vol 41, Iss 3, Pp 1035-1043 (2017)
Background/Aims: Overproliferation of mesangial cells was believed to play an important role in the progress of diabetic nephropathy, one of the primary complications of diabetes. Hydrogen sulfide (H2S), a well-known and pungent gas with the distinct
Externí odkaz:
https://doaj.org/article/8696e365fb3b4ef2b49abd6d0a1ea4cd
Autor:
Shaofei Wang, Jiajun Fan, Xiaobin Mei, Jingyun Luan, Yubin Li, Xuyao Zhang, Wei Chen, Yichen Wang, Guangxun Meng, Dianwen Ju
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Aristolochic acid nephropathy (AAN), as a rapidly progressive interstitial nephropathy due to excessive ingestion of aristolochia herbal medications, has recently raised considerable concerns among clinicians and researchers as its underlying pathoge
Externí odkaz:
https://doaj.org/article/21e3f69c5c614293be5458512ce52e36
A bifunctional fusion protein protected against diabetic nephropathy by suppressing NLRP3 activation
Autor:
Yilan Shen, Yuqing Xu, Pei Shen, Peiling Shen, Qi Bian, Lei Han, Zhonglian Cao, Jiajun Fan, Xian Zeng, Yuting Zhang, Zhiyong Guo, Dianwen Ju, Xiaobin Mei
Publikováno v:
Applied Microbiology and Biotechnology. 107:2561-2576
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d68dd510a0e7288177672493f46341a
https://doi.org/10.1007/s00253-023-12431-5
https://doi.org/10.1007/s00253-023-12431-5