Zobrazeno 1 - 10
of 139
pro vyhledávání: '"XiaoYun Xing"'
Autor:
Changxu Fan, Xiaoyun Xing, Samuel J. H. Murphy, Jennifer Poursine-Laurent, Heather Schmidt, Bijal A. Parikh, Jeesang Yoon, Mayank N. K. Choudhary, Naresha Saligrama, Sytse J. Piersma, Wayne M. Yokoyama, Ting Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Comparative genomics has revealed the rapid expansion of multiple gene families involved in immunity. Members within each gene family often evolved distinct roles in immunity. However, less is known about the evolution of their epigenome and
Externí odkaz:
https://doaj.org/article/2e1544ec47b24a0fa0e54cc35c3f6b85
Autor:
Jennifer A. Karlow, Erica C. Pehrsson, Xiaoyun Xing, Mark Watson, Siddhartha Devarakonda, Ramaswamy Govindan, Ting Wang
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 5, Pp 991-1013 (2023)
Epigenetic alterations are widespread in cancer and can complement genetic alterations to influence cancer progression and treatment outcome. To determine the potential contribution of DNA methylation alterations to tumor phenotype in non-small cell
Externí odkaz:
https://doaj.org/article/2b96d31140bc49209cf99dd5d27d91da
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Psychostimulant methamphetamine (METH) is neurotoxic to the brain and, therefore, its misuse leads to neurological and psychiatric disorders. The gene regulatory network (GRN) response to neurotoxic METH binge remains unclear in most brain r
Externí odkaz:
https://doaj.org/article/600fe16d85ac4f7c92a6436c724c029c
Autor:
Jisu Oh, Amy E. Riek, Kevin T. Bauerle, Adriana Dusso, Kyle P. McNerney, Ruteja A. Barve, Isra Darwech, Jennifer E. Sprague, Clare Moynihan, Rong M. Zhang, Greta Kutz, Ting Wang, Xiaoyun Xing, Daofeng Li, Marguerite Mrad, Nicholas M. Wigge, Esmeralda Castelblanco, Alejandro Collin, Monika Bambouskova, Richard D. Head, Mark S. Sands, Carlos Bernal-Mizrachi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Environmental factors may alter the fetal genome to cause metabolic diseases. It is unknown whether embryonic immune cell programming impacts the risk of type 2 diabetes in later life. We demonstrate that transplantation of fetal hematopoiet
Externí odkaz:
https://doaj.org/article/006bb5f74e894a5ca7b478ca55888534
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Here the authors show transposable elements, formerly considered junk DNA, are a source of CTCF binding sites that contribute to species-specific 3D-genome structure, and may impact gene regulation during the course of mammalian evolution.
Externí odkaz:
https://doaj.org/article/3e5b04c52e4b40f4bb3b5cc423a9dd70
Autor:
Chen Dong, Shuhua Fu, Rowan M. Karvas, Brian Chew, Laura A. Fischer, Xiaoyun Xing, Jessica K. Harrison, Pooja Popli, Ramakrishna Kommagani, Ting Wang, Bo Zhang, Thorold W. Theunissen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here the authors perform a genome-wide CRISPR-Cas9 knockout screen to systematically identify and characterize essential and growth-restricting genes in human trophoblast cells. They identify TEAD1 as a key regulator that plays an important role in t
Externí odkaz:
https://doaj.org/article/bd32546a95904b3d9c16e6c741f46e37
Publikováno v:
Frontiers in Energy Research, Vol 10 (2022)
With the purpose of risk management for fossil energy investors, this paper examines the dynamic spillover effect and asymmetric connectedness between fossil energy, green financial and major traditional financial markets in China. By employing the s
Externí odkaz:
https://doaj.org/article/738709115b9f44e9bb4d64328225b5a7
Autor:
Hyo Sik Jang, Yujie Chen, Jiaxin Ge, Alicia N. Wilkening, Yiran Hou, Hyung Joo Lee, You Rim Choi, Rebecca F. Lowdon, Xiaoyun Xing, Daofeng Li, Charles K. Kaufman, Stephen L. Johnson, Ting Wang
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Background Zebrafish pigment cell differentiation provides an attractive model for studying cell fate progression as a neural crest progenitor engenders diverse cell types, including two morphologically distinct pigment cells: black melanoph
Externí odkaz:
https://doaj.org/article/4eea0e0d91b448bb8acd9cda8b5efd51
Autor:
Xin Huang, Kyoung-mi Park, Paul Gontarz, Bo Zhang, Joshua Pan, Zachary McKenzie, Laura A. Fischer, Chen Dong, Sabine Dietmann, Xiaoyun Xing, Pavel V. Shliaha, Jihong Yang, Dan Li, Junjun Ding, Tenzin Lungjangwa, Maya Mitalipova, Shafqat A. Khan, Sumeth Imsoonthornruksa, Nick Jensen, Ting Wang, Cigall Kadoch, Rudolf Jaenisch, Jianlong Wang, Thorold W. Theunissen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Although the interactors of pluripotency factors have been identified in mouse embryonic stem cells (ESCs), their interactors in human ESCs remain unexplored. Here the authors map OCT4 protein interactions in naïve and primed human ESCs to find spec
Externí odkaz:
https://doaj.org/article/475ca4c998cb484bb6963209f6ebdc13
Autor:
Shasha Li, Michael D Bern, Benpeng Miao, Changxu Fan, Xiaoyun Xing, Takeshi Inoue, Sytse J Piersma, Ting Wang, Marco Colonna, Tomohiro Kurosaki, Wayne M Yokoyama
Publikováno v:
eLife, Vol 11 (2022)
BTB domain And CNC Homolog 2 (Bach2) is a transcription repressor that actively participates in T and B lymphocyte development, but it is unknown if Bach2 is also involved in the development of innate immune cells, such as natural killer (NK) cells.
Externí odkaz:
https://doaj.org/article/4803a607778c48e2a158ffe3d291b821