Antibacterial activity and mechanisms of D-3263 against Staphylococcus aureus

Autor: Xiaoju Liu, Yanpeng Xiong, Renhai Peng, Yufang Zhang, Shuyu Cai, Qiwen Deng, Zhijian Yu, Zewen Wen, Zhong Chen, Tieying Hou

Publikováno v: BMC Microbiology, Vol 24, Iss 1, Pp 1-12 (2024)

Abstract Multi-drug-resistant Staphylococcus aureus infections necessitate novel antibiotic development. D-3263, a transient receptor potential melastatin member 8 (TRPM8) agonist, has potential antineoplastic properties. Here, we reported the antiba

Externí odkaz: https://doaj.org/article/fe745a2ef7de4468b28a70221edf0225

Integrating network pharmacology, molecular docking and non-targeted serum metabolomics to illustrate pharmacodynamic ingredients and pharmacologic mechanism of Haizao Yuhu Decoction in treating hyperthyroidism

Autor: Wenbin Huang, Xiaoju Liu, Xingjia Li, Ruixiang Zhang, Guofang Chen, Xiaodong Mao, Shuhang Xu, Chao Liu

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

ObjectiveTo explore the pharmacodynamic ingredients and pharmacologic mechanism of Haizao Yuhu Decoction (HYD) in treating hyperthyroidism via an analysis integrating network pharmacology, molecular docking, and non-targeted serum metabolomics.Method

Externí odkaz: https://doaj.org/article/d9f97abd0dff4b288e1e545e2c9e7cb0

Identification of hypoxia-related genes and exploration of their relationship with immune cells in ischemic stroke

Autor: Kai Yang, Zhaoqi Zhang, Xiaoju Liu, Tong Wang, Zhicheng Jia, Xin Li, Wei Liu

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Abstract Ischemic stroke (IS) is a major threat to human health, and it is the second leading cause of long-term disability and death in the world. Impaired cerebral perfusion leads to acute hypoxia and glucose deficiency, which in turn induces a str

Externí odkaz: https://doaj.org/article/8e31cc9862724c01945ad6c57ce6b4be

Insights into the mechanism in electrochemical CO2 reduction over single-atom copper alloy catalysts: A DFT study

Autor: Tianfu Liu, Guohui Song, Xiaoju Liu, Zhou Chen, Yu Shen, Qi Wang, Zhangquan Peng, Guoxiong Wang

Publikováno v: iScience, Vol 26, Iss 10, Pp 107953- (2023)

Summary: Copper single-atom alloy catalysts (M@Cu SAAs) have shown great promise for electrochemical CO2 reduction reaction (CO2RR). However, a clear understanding of the CO2RR process on M@Cu SAAs is still lacking. This study uses density functional

Externí odkaz: https://doaj.org/article/f8d13712e3ef4b3885c6c6dcdc83178c

Overview of recent experimental results on the EAST Tokamak

Autor: X. Gong, on behalf of EAST Team and Collaborators, The EAST Team:, Yuntao Song, Baonian Wan, Jiangang Li, Yuanxi Wan, Xinchao Wu, Fukun Liu, Junling Chen, Jiansheng Hu, Guosheng Xu, Kun Lu, Xianzu Gong, Bingjia Xiao, Yu Wu, Xiang Gao, Damao Yao, Nong Xiang, Liqun Hu, Chundong Hu, Jiefeng Wu, Biao Shen, Ge Gao, Yiyun Huang, Liuwei Xu, Qiyong Zhang, Cheonho Bae, Bin Cao, Lei Cao, Jiafeng Chang, Dalong Chen, Ran Chen, Xiaojiao Chen, Yebin Chen, Yue Chen, Yunxin Cheng, Yong Cheng, Bojiang Ding, Fang Ding, Rui Ding, Shijun Du, Yanmin Duan, Jia Fu, Daming Gao, Wei Gao, Yongqi Gu, Bin Guo, Fei Guo, Yong Guo, Xiaofeng Han, Shiying He, Ailan Hu, Chang Hu, Guanghai Hu, Huaichuan Hu, Qingsheng Hu, Yanlan Hu, Zhenhua Hu, Juan Huang, Liansheng Huang, Ming Huang, Ronglin Huang, Xiang Ji, Hua Jia, Caichao Jiang, Yinxian Jie, Songqing Ju, Defeng Kong, Erzhong Li, Guoqiang Li, Jiahong Li, Junjun Li, Miaohui Li, Pan Li, Kedong Li, Shi Li, Yadong Li, Lizhen Liang, Yanchuan Liao, Shiyao Lin, Xin Lin, Bili Ling, Haiqing Liu, Huajun Liu, Jianwen Liu, Liang Liu, Shaocheng Liu, Sheng Liu, Wenbin Liu, Xiaoju Liu, Xiaoyan Liu, Yong Liu, Zhihong Liu, Zhimin Liu, Jianhua Lu, Zhengping Luo, Dengkui Ma, Huafeng Mao, Wendong Ma, Songtao Mao, Yuzhou Mao, Tingfeng Ming, Chao Pan, Chengkang Pan, Shengmin Pan, Jing Qian, Jinping Qian, Chengming Qin, Zhiyong Qiu, Qilong Ren, Zhicai Sheng, Shihua Song, Pengjun Sun, Xiaoyang Sun, Youwen Sun, Tian Tang, Ling Tao, Ang Ti, Baoguo Wang, Feng Wang, Fudi Wang, Huihui Wang, Jian Wang, Liang Wang, Linsen Wang, Mao Wang, Ping Wang, Xiaojie Wang, Shouxin Wang, Yating Wang, Yuehang Wang, Yong Wang, Zhengchu Wang, Jianglong Wei, Jing Wei, Xuechao Wei, Bin Wu, Dajun Wu, Hao Wu, Jinhua Wu, Xiangming Wu, Yibing Wu, Zege Wu, Weibin Xi, Tianyang Xia, Yezheng Xiao, Yahong Xie, Yuanlai Xie, Handong Xu, Liqing Xu, Weiye Xu, Ning Yan, Rong Yan, Jianhua Yang, Lei Yang, Qingxi Yang, Yao Yang, Zhongshi Yang, Min Yu, Yaowei Yu, Qiping Yuan, Shuai Yuan, Qing Zang, Bin Zhang, Jian Zhang, Jizong Zhang, Liyuan Zhang, Ling Zhang, Ruirui Zhang, Shoubiao Zhang, Tao Zhang, Wei Zhang, Xinjun Zhang, Xiuqing Zhang, Yang Zhang, Zuchao Zhang, Hailin Zhao, Lianmin Zhao, Guoqiang Zhong, Ruijie Zhou, Haishan Zhou, Tianhu Zhou, Yue Zhou, Dahuan Zhu, Haisheng Zhu, Ping Zhu, Zeying Zhu, Huidong Zhuang, Zibo Zhou, Zhiyong Zhou, Zhiwei Zhou, Guizhong Zuo, International and Domestic Collaborators:, Huishan Cai, Weixing Ding, Tao Lan, Adi Liu, Wandong Liu, Shaojie Wang, Minyou Ye, Yi Yu, Ge Zhuang, Wei Chen, Guangjiu Lei, Lin Nie, Min Xu, Huang Yuan, Nanhua Yao, Zhe Gao, Long Zeng, Tieshuan Fan, Liu Chen, Guoyong Fu, Zhiwei Ma, Zengmao Sheng, Yong Xiao, Xiaogang Wang, Zhongyong Chen, Yonghua Ding, Xiwei Hu, Zijiang Wang, Fangchuan Zhong, Hongbin Ding, Dezhen Wang, Zhengxiong Wang, Chenggang Jin, Xuemei Wu, Xiaofei Yang, Jianhua Zhang, Qingyuan Hu, Xi Yuan, Changqi Chen, Shuyi Gan, Xudi Wang, Congzhong Wu, Chongwei Zhang, Ting Zhang, Wu Zhu, Erhua Kong, Kaisong Wang, Chuanli Wang, Hongtao Yang, Lixiang Zhang, Yuhong Xu, Paul Anderson, Gheni Abla, Vincent Chan, John L. Doane, Andrea Garofalo, Punit Gohil, Chung Lih Hsieh, Ruey Hong, David Humphreys, Alan Walter Hyatt, Gary Jackson, Lang Lao, Yueqiang Liu, James Leuer, John Lohr, Mohamad Ali Mahdavi, Robert Olstad, Ben Penaflor, Ron Prater, David Piglowski, Michael Schaffe, Tim Scoville, Wayne Solomon, Mike Walker, Anders Welander, Manfred Bitter, Robert Budny, Robert A. Ellis, Nat Fisch, Rich Hawryluk, Kenneth W. Hill, Joel Hosea, Michael A. Jaworski, Egemen Kolemen, Rajesh Maingi, Dennis Mansfield, Dana M. Mastrovito, Jonathan Menard, Dennis Mueller, Novmir Pablant, Lane Roquemore, Filippo Scotti, Gary Taylor, Kevin Tritz, Randy Wilson, Michael Zarnstorff, Seung Gyou Baek, Beck Bill, Paul T. Bonoli, Robert Granetz, Ron Parker, Shunichi Shiraiwa, Josh Stillerman, Greg Wallace, Stephen Wukitch, Lihua Zhou, He Huang, Kenneth Gentle, Ken Liao, Perry Philippe, William L. Rowan, Linjin Zheng, Patrick H. Diamond, George R. Tynan, Nicolas Fedorczak, Peter Manz, Lei Zhao, David Brower, William W. Heidbrink, Yubao Zhu, Calvin W. Domier, Neville C. Luhmann, Chris Holcomb, Xueqiao Xu, Eric Wang, Max E. Fenstermarcher, Mickey Wade, Donald L. Hillis, Steve Meitner, Igor V. Vinyar, Vladimir Davydenko, Igor Shikhovtsev, Naoko Ashikawa, Kasahara Hiroshi, Katsumi Ida, Shinichiro Kado, Tomita Kawamura, Saito Kenji, Ryuhei Kumazawa, Ogawa Kunihiro, Isobe Mitsutaka, Shigeru Morita, Haruhisa Nakano, Masaki Osakabe, Mizuki Sakamoto, Yasuhiko Takeiri, Kazuo Toi, Katsuyoshi Tsumori, Nobuta Yuji, Masaya Hanada, Mitsuru Kikuchi, Atsushi Kojima, Kazuhiro Watanabe, Jean-Francois Artaud, Vincent Basiuk, F. Bouquey, B. Bremond, Laurent Colas, Joan Decker, D. Douai, Annika Ekedahl, Christel Fenzi, Eric Gauthier, Gerardo Giruzzi, Marc Goniche, Dominique Guilhem, Walid Helou, Julien Hillairet, Tuong Hoang, Philippe Huynh, Frederic Imbeaux, Xavier Litaudon, Roland Magne, Yves Peysson, K. Vueillie, Xiaolan Zou, Alberto Loarte, Richard Pitts, Tom Wauters, Franz Braun, R. Bilato, Volodymyr Bobkov, J.M. Noterdaeme, Qingquan Yu, Yunfeng Liang, Jonny Pearson, Michael Rack, Joseph Banks, John Fessey, Charles Monroe, Damian King, Stefan Schmuck, Hongjuan Sun, Paul Trimble, Tom Todd, Jun-Gyo Bak, Suk-Ho Hong, Sangong Lee, Bae Young Soon, Oh Byung Hoon, Chang Doo Hee, Lee Kwang Won, Luca Amicucci, Giuseppe Calabro, Silvio Ceccuzzi, Roberto Cesario, Flavio Crisanti, Edmondo Giovannozzi, Giuseppe Ramogida, Gianmaria De Tommasi, Angelo Antonio Tuccillo, Bruno Viola, Raffaele Albanese, Roberto Ambrosino, Lucio Barbato, Stefano Mastrostefano, Alfredo Pironti, Vincenzo Pericoli Ridolfini, Rory Scannell, Fabio Villone, Volker Naulin, Anders H. Nielsen, Roman Zagorsky, Sandor Zoletnik, Chijin Xiao, B. Madsen, M. Salewski, Eugenio Schuster

Publikováno v: Nuclear Fusion, Vol 64, Iss 11, p 112013 (2024)

Since the last IAEA-FEC in 2021, significant progress on the development of long pulse steady state scenario and its related key physics and technologies have been achieved, including the reproducible 403 s long-pulse steady-state H-mode plasma with

Externí odkaz: https://doaj.org/article/e7d8d2e749f749ba980b1e4d3ca6cf2b