Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Xiao-yu He"'
Autor:
Xin Zang, Xiao-Yu He, Cheng-Mei Xiao, Qing Lin, Meng-Yue Wang, Cheng-Yan Liu, Ling-Yi Kong, Zhong Chen, Yuan-Zheng Xia
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background The clinical response rate to immune checkpoint blockade (ICB) therapy in melanoma remains low, despite its widespread use. Circular non-coding RNAs (circRNAs) are known to play a crucial role in cancer progression and may be a ke
Externí odkaz:
https://doaj.org/article/d54be9b6b9fb43a285fa7b175357b315
Autor:
Liu Yang, Ya-Nan Ou, Bang-Sheng Wu, Wei-Shi Liu, Yue-Ting Deng, Xiao-Yu He, Yi-Lin Chen, Jujiao Kang, Chen-Jie Fei, Ying Zhu, Lan Tan, Qiang Dong, Jianfeng Feng, Wei Cheng, Jin-Tai Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The genetic contribution of protein-coding variants to immune-mediated diseases (IMDs) remains underexplored. Through whole exome sequencing of 40 IMDs in 350,770 UK Biobank participants, we identified 162 unique genes in 35 IMDs, among whic
Externí odkaz:
https://doaj.org/article/0382ad71c24141108a559c2764251661
Autor:
Jian Liu, Xiao-Yu He, Ke-Laier Yang, Yue Zhao, En-Yu Dai, Wen-Jia Chen, Aditya Kumar Raj, Di Li, Min Zhuang, Xin-Hua Yin, Hong Ling
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT Respiratory tract infections are the most common triggers for heart failure in elderly people. The healthy respiratory commensal microbiota can prevent invasion by infectious pathogens and decrease the risk of respiratory tract infections. H
Externí odkaz:
https://doaj.org/article/8699c3772dd34917ba269eb4ed9ead1b
Autor:
Xiao-Yu He, Bang-Sheng Wu, Liu Yang, Yu Guo, Yue-Ting Deng, Ze-Yu Li, Chen-Jie Fei, Wei-Shi Liu, Yi-Jun Ge, Jujiao Kang, Jianfeng Feng, Wei Cheng, Qiang Dong, Jin-Tai Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Previous genetic studies of venous thromboembolism (VTE) have been largely limited to common variants, leaving the genetic determinants relatively incomplete. We performed an exome-wide association study of VTE among 14,723 cases and 334,315
Externí odkaz:
https://doaj.org/article/52e2d900e96d4b37bc1c83682135fd19
Autor:
Dan-Dan Zhang, Xiao-Yu He, Liu Yang, Bang-Sheng Wu, Yan Fu, Wei-Shi Liu, Yu Guo, Chen-Jie Fei, Ju-Jiao Kang, Jian-Feng Feng, Wei Cheng, Lan Tan, Jin-Tai Yu
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011339 (2024)
BackgroundVaricose veins (VV) are one of the common human diseases, but the role of genetics in its development is not fully understood.MethodsWe conducted an exome-wide association study of VV using whole-exome sequencing data from the UK Biobank, a
Externí odkaz:
https://doaj.org/article/0162a43e32894509b11f0077609c919d
Publikováno v:
Journal of Bone Oncology, Vol 46, Iss , Pp 100604- (2024)
Osteosarcoma (OS), a malignant tumor, originates from the bone marrow. Currently, treatment for OS remains limited, making it urgent to understand the immune response in the tumor microenvironment of patients with OS. A comprehensive bioinformatics a
Externí odkaz:
https://doaj.org/article/ef2bba871b264bea969405204d14d54d
Autor:
Yi-Xuan Qiang, Jia You, Xiao-Yu He, Yu Guo, Yue-Ting Deng, Pei-Yang Gao, Xin-Rui Wu, Jian-Feng Feng, Wei Cheng, Jin-Tai Yu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Blood-based biomarkers for dementia are gaining attention due to their non-invasive nature and feasibility in regular healthcare settings. Here, we explored the associations between 249 metabolites with all-cause dementia (ACD), A
Externí odkaz:
https://doaj.org/article/96b1ad83ac0f45d99f88c5658a133a61
Autor:
Xiao-Yu He, Bang-Sheng Wu, Kevin Kuo, Wei Zhang, Qing Ma, Shi-Tong Xiang, Yu-Zhu Li, Zi-yi Wang, Qiang Dong, Jian-Feng Feng, Wei Cheng, Jin-Tai Yu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background The correlations between genetic risk for Alzheimer’s disease (AD) with comprehensive brain regions at a regional scale are still not well understood. We aim to explore whether these associations vary across different age stages
Externí odkaz:
https://doaj.org/article/9626c04116a24c099a93de98fb7a1acf
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
The diagnosis of pulmonary alveolar proteinosis (PAP) is based on biopsies. Compared with other methods of taking biopsies, transbronchial lung cryobiopsy (TBLC) has a higher diagnostic rate and the likelihood of pneumothorax. Selective bronchial occ
Externí odkaz:
https://doaj.org/article/7c70abf64090486fba327e1153e594f8
Autor:
Xiao-Yu He, Kevin Kuo, Liu Yang, Ya-Ru Zhang, Bang-Sheng Wu, Shi-Dong Chen, Wei Cheng, Jian-Feng Feng, Jin-Tai Yu
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Prevention of dementia is a public health priority, and the identification of potential biomarkers may provide benefits for early detection and prevention. This study investigates the association of common serum laboratory tests with the ris
Externí odkaz:
https://doaj.org/article/04054964c8074bacb5e8d7d8acd0cbea