Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Xiao-xin Yan"'
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Subarachnoid hemorrhage (SAH) is one of the most severe type of cerebral strokes, which can cause multiple cellular changes in the brain leading to neuronal injury and neurological deficits. Specifically, SAH can impair adult neurogenesis in
Externí odkaz:
https://doaj.org/article/926b79a954904a3593af06fe1f6b0997
Autor:
Xingyu Zhang, Li Zou, Li Tang, Min Xiong, Xiao-Xin Yan, Lanxia Meng, Guiqin Chen, Jing Xiong, Shuke Nie, Zhaohui Zhang, Qiang Chen, Zhentao Zhang
Publikováno v:
PLoS Biology, Vol 22, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/e0ff0fbafbd9416aa99275a70842e6fc
Autor:
Xiaobo Han, Jean de Dieu Habimana, Amy L. Li, Rongqi Huang, Omar Mukama, Weiyue Deng, Ling Wang, Yuying Zhang, Wei Wang, Sihao Deng, Kexin Peng, Bing Ni, Shusheng Zhang, Jufang Huang, Xiao-xin Yan, Zhiyuan Li
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-12 (2022)
Abstract Defects in ataxin-3 proteins and CAG repeat expansions in its coding gene ATXN3 cause Spinocerebellar Ataxia Type 3 (SCA3) or Machado-Joseph disease (MJD) polyglutamine neurodegenerative disease. The mutant proteins aggregate as inclusion bo
Externí odkaz:
https://doaj.org/article/961046198a1144d0a3db0b11efd8cb6f
Autor:
Yuying Zhang, Weiyue Deng, Wei Wang, Aishi Song, Omar Mukama, Sihao Deng, Xiaobo Han, Jean De Dieu Habimana, Kexin Peng, Bin Ni, Shusheng Zhang, Jufang Huang, Xiao-xin Yan, Zhiyuan Li
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract Background Non-pathological cognitive decline is a neurodegenerative condition associated with brain aging owing to epigenetic changes, telomere shortening, stem cells exhaustion, or altered differentiation. Human umbilical cord mesenchymal
Externí odkaz:
https://doaj.org/article/6df37934df534cb2a20e1a6dad865215
Autor:
Juan Jiang, Chen Yang, Jia-Qi Ai, Qi-Lei Zhang, Xiao-Lu Cai, Tian Tu, Lily Wan, Xiao-Sheng Wang, Hui Wang, Aihua Pan, Jim Manavis, Wei-Ping Gai, Chong Che, Ewen Tu, Xiao-Ping Wang, Zhen-Yan Li, Xiao-Xin Yan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Extracellular β-amyloid (Aβ) deposition and intraneuronal phosphorylated-tau (pTau) accumulation are the hallmark lesions of Alzheimer’s disease (AD). Recently, “sorfra” plaques, named for the extracellular deposition of sortilin c-terminal f
Externí odkaz:
https://doaj.org/article/5b526986a2b54f6b9f2e43d6bf886cd3
Autor:
Lily Wan, Rou-Jie Huang, Chen Yang, Jia-Qi Ai, Qian Zhou, Jiao-E Gong, Jian Li, Yun Zhang, Zhao-Hui Luo, Ewen Tu, Aihua Pan, Bo Xiao, Xiao-Xin Yan
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Adult hippocampal neurogenesis (AHN) is important for multiple cognitive functions. We sort to establish a minimal or non-invasive radiation approach to ablate AHN using guinea pigs as an animal model. 125I seeds with different radiation dosages (1.0
Externí odkaz:
https://doaj.org/article/f5570af22ddb4951a2234c8216a121a6
Autor:
Jia-Qi Ai, Rongcan Luo, Tian Tu, Chen Yang, Juan Jiang, Bo Zhang, Rui Bi, Ewen Tu, Yong-Gang Yao, Xiao-Xin Yan
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
Doublecortin (DCX) is transiently expressed in new-born neurons in the subventricular zone (SVZ) and subgranular zone (SGZ) related to adult neurogenesis in the olfactory bulb (OB) and hippocampal formation. DCX immunoreactive (DCX+) immature neurons
Externí odkaz:
https://doaj.org/article/f9568d51fd1e4fae94636fd29d80752c
Autor:
Lily Wan, Jia-Qi Ai, Chen Yang, Juan Jiang, Qi-Lei Zhang, Zhao-Hui Luo, Rou-Jie Huang, Tian Tu, Aihua Pan, Ewen Tu, Jim Manavis, Bo Xiao, Xiao-Xin Yan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Shank3 is a postsynaptic scaffolding protein of excitatory synapses. Mutations or variations of SHANK3 are associated with various psychiatric and neurological disorders. We set to determine its normal expression pattern in the human brain, and its c
Externí odkaz:
https://doaj.org/article/dd43ca1e535641c2a7239293cca61506
Autor:
Xiaobo Han, Jean de Dieu Habimana, Amy L. Li, Rongqi Huang, Omar Mukama, Weiyue Deng, Ling Wang, Yuying Zhang, Wei Wang, Sihao Deng, Kexin Peng, Bin Ni, Shusheng Zhang, Jufang Huang, Xiao-xin Yan, Zhiyuan Li
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f877499a34e6457187d519d72974d2b0
Autor:
Lily Wan, Rou-Jie Huang, Zhao-Hui Luo, Jiao-e Gong, Aihua Pan, Jim Manavis, Xiao-Xin Yan, Bo Xiao
Publikováno v:
Neural Plasticity, Vol 2021 (2021)
The levels of reproduction-associated hormones in females, such as estrogen, progesterone, prolactin, and oxytocin, change dramatically during pregnancy and postpartum. Reproduction-associated hormones can affect adult hippocampal neurogenesis (AHN),
Externí odkaz:
https://doaj.org/article/2a68f93ee1514f50a6b5950fe1ec075a