Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Xiao-meng Chong"'
Publikováno v:
Frontiers in Chemistry, Vol 8 (2021)
In this study, two isomeric impurities were identified in cefotiam hydrochloride injection preparation and were characterized. Column-switching HPLC-MS and NMR techniques were used to identify the impurity 1 as the Δ3(4) isomers of cefotiam. Using s
Externí odkaz:
https://doaj.org/article/6782dd8235ac4127a22fd2e6477d5bab
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
The accuracy of quantitative models for near-infrared (NIR) spectroscopy is dependent upon calibration samples with concentration variations. Conventional sample-collection methods have shortcomings (especially time-consumption), which creates a “b
Externí odkaz:
https://doaj.org/article/4b7d460dd93d48c49b499cbc3781f6af
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 9 (2021)
Frontiers in Chemistry, Vol 9 (2021)
Objective: To establish a method for the determination of the chemical structure of vancomycin hydrochloride.Methods: Nuclear magnetic resonance spectroscopy and mass spectrometry were conducted to analyze the chemical structure of vancomycin hydroch
Autor:
Xiao-meng, Chong, Jin, Li, Yan, Wang, Chen, Wang, Li-xin, Wang, Shang-chen, Yao, Chang-qin, Hu
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 51(7)
The critical attribute was analyzed in clavulanate potassium tablet of amoxicillin according to the principle QbD. By investigation of the drug impurity profile, the cycle-closed dimer and penicilloic acid of amoxicillin were considered to be the cri
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
The accuracy of quantitative models for near-infrared (NIR) spectroscopy is dependent upon calibration samples with concentration variations. Conventional sample-collection methods have shortcomings (especially time-consumption), which creates a "bot
Publikováno v:
AAPS PharmSciTech. 18(4)
The cycle-closed dimer of amoxicillin influences its critical quality and is an important impurity in amoxicillin and clavulanate potassium tablets. The quality of the tablets could be rapidly evaluated using the impurity as an indicator. Here, we re
Publikováno v:
Rapid Communications in Mass Spectrometry. 24:2143-2150
The structural fragment ions of nine cephalosporins were studied by electrospray ionization quadrapole trap mass spectrometry (Q-Trap MSn) in positive mode. The influence of substituent groups in the 3-position on fragmentation pathway B, an α-cleav
Publikováno v:
Vibrational Spectroscopy. 51:313-317
Publikováno v:
Vibrational Spectroscopy. 49:196-203
A universal classification model has been developed for identification of 26 different products of cephalosporins for injection using near-infrared (NIR) spectroscopy. A total of 324 batches of the 26 products, from 166 manufacturers in China, were u
Autor:
Chang-Qin Hu, Xiao-Meng Chong
Publikováno v:
Chromatographia. 68:759-766
β-Lactam antibiotics are among the most frequently used in clinical therapy. Thirty-three cephalosporin and eleven penicillin antibiotics frequently used in China have been used to create an ESI-MS library. A single-quadrupole mass analyzer was used