Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Xiao-kang Zhu"'
Publikováno v:
Jisuanji kexue, Vol 49, Iss 9, Pp 326-332 (2022)
Embedded devices have become visible everywhere,and they are used in a range of security-critical and privacy-sensitive applications.However,recent studies show that many embedded devices have backdoor,of which hard-coded backdoor(password backdoor)
Externí odkaz:
https://doaj.org/article/440dd76827d04329ba0d895ed205f0e0
Publikováno v:
Journal of Analysis and Testing. 6:111-119
Autor:
Xiao-kang Zhu, Bin Fu, Ramon Felipe Bicudo Da Silva, Ying-man Guo, Chan-yuan Qin, Ting Feng, Hai-bing Yu, Kuang Xiao
Publikováno v:
Journal of Mountain Science. 19:925-944
Publikováno v:
Carbohydrate Polymers. 88:75-83
A hydrogel sheet composed of chitosan, honey and gelatin (HS; 0.5:20:20, w/w) was developed as a burn wound dressing. HS showed powerful antibacterial efficacy up to 100% to Staphylococcus aureus and Escherichia coli, significantly superior to chitos
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:4267-4273
A series of novel podophyllotoxin derivatives containing structural modifications at C-4 (7-14), C-4' (16-17), and the methylenedioxy A-ring (23-28) was synthesized and tested for inhibition of HIV replication. Four of these compounds (25-28) were pr
Autor:
Yung-Chi Cheng, Kuo Hsiung Lee, Sung Jin Cho, Huey-Hwa Cheng, Yoko Tachibana, Jian Guan, Kenneth F. Bastow, Marc Gurwith, Xiao-Kang Zhu
Publikováno v:
Journal of Medicinal Chemistry. 42:2441-2446
As a continuation of our structure-activity relationship studies, several new 4-beta-substituted 4'-O-demethyl-4-desoxypodophyllotoxins bearing mono-, di-, or trisubstituted anilines have been synthesized and evaluated as inhibitors of DNA topoisomer
Autor:
Xiao Kang Zhu, Arnold Brossi, Andrew T. McPhail, Kenneth F. Bastow, Ernest Hamel, Jian Guan, Yoko Tachibana, Pascal Verdier-Pinard, Kuo Hsiung Lee
Publikováno v:
Collection of Czechoslovak Chemical Communications. 64:217-228
Two allocolchicinoids 6 and 8, prepared from colchicine, together with allo compounds 9-11, made from 6 by reduction and regiodemethylation, were evaluated for antitubulin and antitumor activities. Structures of 6, 8, and 10 were confirmed by X-ray c
Autor:
Arnold Brossi, Kuo Hsiung Lee, Xiao Kang Zhu, Kenneth F. Bastow, Ernest Hamel, Yoko Tachibana, Jian Guan
Publikováno v:
Bioorganic & Medicinal Chemistry. 6:2127-2131
Demethylation of colchiceinamide (2) and its analogues (3-10) afforded a novel class of mammalian DNA topoisomerase II inhibitors (2a-10a) without displaying tubulin inhibitory activity. All target compounds inhibited the catalytic activity of topois
Publikováno v:
Synthetic Communications. 28:1585-1591
An improved, highly selective demethylation of thiocolchicine (1) to the diphenol 5 is described. Oxidation of 2 to para-quinone 6 and of 4 and 5 to ortho-quinones 8 and 10 is first reported. Also, 2-demethylthiocolchicine (3) was oxidized to the qui
Autor:
Jian Guan, Xiao Kang Zhu, Arnold Brossi, Yoko Tachibana, Ernest Hamel, Kenneth F. Bastow, Kuo Hsiung Lee
Publikováno v:
Journal of Medicinal Chemistry. 41:1956-1961
Several 1,2,3-tridemethyldeacetylthiocolchicine derivatives have been synthesized and evaluated for cytotoxic activity against various human tumor cell lines and for their inhibitory effects on DNA topoisomerases in vitro. Exhaustive demethylation of