Výsledky vyhledávání - "Xiao-jie Yan"

Akademický článek

Acceptance and attitude towards the traditional chinese medicine among asymptomatic COVID-19 patients in Shanghai Fangcang hospital

Autor: Bo Pan, Hong-wei Yin, Yue Yu, Xing Xiang, Cui Yu, Xiao-Jie Yan, Xiao-feng Zhai, Yuan Bai, Jing Hong

Publikováno v: BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-11 (2023)

Abstract Objective The Coronavirus Disease 2019 (COVID-19) has brought severe damage to global health and socioeconomics. In China, traditional Chinese medicine (TCM) is the most important complementary and alternative medicine (CAM) and it has shown

Externí odkaz: https://doaj.org/article/cb062674e3aa4a3cb2c2a3a52508f411

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Akademický článek

CLL stereotyped B-cell receptor immunoglobulin sequences are recurrent in the B-cell repertoire of healthy individuals: Apparent lack of central and early peripheral tolerance censoring

Autor: Stefano Vergani, Davide Bagnara, Andreas Agathangelidis, Anita Kar Yun Ng, Gerardo Ferrer, Andrea N. Mazzarello, Florencia Palacios, Sophia Yancopoulos, Xiao-Jie Yan, Jaqueline C. Barrientos, Kanti R. Rai, Kostas Stamatopoulos, Nicholas Chiorazzi

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

IntroductionThe leukemic cells of patients with chronic lymphocytic leukemia (CLL) are often unique, expressing remarkably similar IGHV-IGHD-IGHJ gene rearrangements, “stereotyped BCRs”. The B-cell receptors (BCRs) on CLL cells are also distincti

Externí odkaz: https://doaj.org/article/13e9226ca5f64baa9b66e56ee46ce5d9

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Akademický článek

Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Patients with CLL with mutated IGHV genes (M-CLL) have better outcomes than patients with unmutated IGHVs (U-CLL). Since U-CLL usually express immunoglobulins (IGs) that are more autoreactive and more effectively transduce signals to leukemic B cells

Externí odkaz: https://doaj.org/article/c619ded3a3974ed5becc2e624f138274

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Akademický článek

Correction to: Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells

Publikováno v: Molecular Medicine, Vol 28, Iss 1, Pp 1-1 (2022)

Externí odkaz: https://doaj.org/article/c3739f0c9598420c8799dd44901b0253

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Akademický článek

Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia

Autor: Eleftheria Polychronidou, Ilias Kalamaras, Andreas Agathangelidis, Lesley-Ann Sutton, Xiao-Jie Yan, Vasilis Bikos, Anna Vardi, Konstantinos Mochament, Nicholas Chiorazzi, Chrysoula Belessi, Richard Rosenquist, Paolo Ghia, Kostas Stamatopoulos, Panayiotis Vlamos, Anna Chailyan, Nanna Overby, Paolo Marcatili, Anastasia Hatzidimitriou, Dimitrios Tzovaras

Publikováno v: BMC Bioinformatics, Vol 19, Iss S14, Pp 67-81 (2018)

Abstract Background Although the etiology of chronic lymphocytic leukemia (CLL), the most common type of adult leukemia, is still unclear, strong evidence implicates antigen involvement in disease ontogeny and evolution. Primary and 3D structure anal

Externí odkaz: https://doaj.org/article/001f703b254943c08d9ed6b5c55f3ad7

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Akademický článek

Binding of CLL Subset 4 B Cell Receptor Immunoglobulins to Viable Human Memory B Lymphocytes Requires a Distinctive IGKV Somatic Mutation

Autor: Rosa Catera, Yun Liu, Chao Gao, Xiao-Jie Yan, Amanda Magli, Steven L. Allen, Jonathan E. Kolitz, Kanti R. Rai, Charles C. Chu, Ten Feizi, Kostas Stamatopoulos, Nicholas Chiorazzi

Publikováno v: Molecular Medicine, Vol 23, Iss 1, Pp 1-12 (2017)

Abstract Amino acid replacement mutations in certain chronic lymphocytic leukemia (CLL) stereotyped B cell receptor (BCR) immunoglobulins (IGs) at defined positions within antigen-binding sites strongly imply antigen selection. Prime examples of this

Externí odkaz: https://doaj.org/article/9e9c41d121d1407f8fb9aa6e622fb796

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Data from Chronic Lymphocytic Leukemia Monitoring with a Lamprey Idiotope-Specific Antibody

Autor: Max D. Cooper, Nicholas Chiorazzi, Xiao-Jie Yan, Rosa Catera, Matthew N. Alder, Brantley R. Herrin, Hirotomo Nakahara

For antigen recognition, lampreys use leucine-rich repeats (LRR) instead of immunoglobulin V-(D)-J domains to generate variable lymphocyte receptors (VLR) of three types: VLRA, VLRB, and VLRC. VLRB-bearing lymphocytes respond to immunization with pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8fa1315c71146b76bf74ba683e8ecd6
https://doi.org/10.1158/2326-6066.c.6548074

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Supplementary Methods, Figures 1 - 4, Tables 1 - 2 from Chronic Lymphocytic Leukemia Monitoring with a Lamprey Idiotope-Specific Antibody

Autor: Max D. Cooper, Nicholas Chiorazzi, Xiao-Jie Yan, Rosa Catera, Matthew N. Alder, Brantley R. Herrin, Hirotomo Nakahara

PDF file - 192K, Figure S1: Flow cytometric analysis of monoclonal VLR39 reactivity with different cell types and cell lines. Figure S2: Flow cytometric analysis of monoclonal VLR39 reactivity with CLL cells with different VH gene sets. Figure S3: CL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003181459521556da1e4ec8239f9278d
https://doi.org/10.1158/2326-6066.22536217

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Figure S1 from Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes

Autor: Kostas Stamatopoulos, Paolo Ghia, Richard Rosenquist, Anastasia Hadzidimitriou, Frederic Davi, Chrysoula Belessi, Nikos Darzentas, Ioanna Chouvarda, Stephan Stilgenbauer, Diane F. Jelinek, Gianluca Gaidano, David Oscier, Nikos Maglaveras, Nicholas Chiorazzi, Elias Campo, Michael Hallek, Sarka Pospisilova, Anton W. Langerak, Hartmut Döhner, Carsten Niemann, Marco Montillo, Livio Trentin, Darko Antic, Ioannis Vlahavas, Achilles Anagnostopoulos, Gunnar Juliusson, Panagiotis Panagiotidis, Marie-Paule Lefranc, Véronique Giudicelli, Charles C. Chu, Karin E. Smedby, Larry Mansouri, Lone Bredo Pedersen, Christiane Pott, Jasmin Bahlo, Monica Facco, Maria Chatzouli, Dirk Kienle, Mark Catherwood, Teodora Karan-Djurasevic, Tatiana Tzenou, Silvio Veronese, Andrey Sudarikov, Niki Stavroyianni, Lydia Scarfo, Fie Juhl Vojdeman, Yorick Sandberg, Alba Navarro, Zadie Davis, Davide Rossi, Myriam Boudjogra, Karla Plevova, Tait Shanafelt, Xiao-Jie Yan, Eugen Tausch, Stavroula Ntoufa, Eva Minga, Lesley-Ann Sutton, Andreas Agathangelidis, Ioannis Kavakiotis, Panagiotis Baliakas, Aliki Xochelli

Distribution of IGHV4-34 CLL according to IGHV mutational status and subset membership.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3d3f916dc7ca72c06758ce21dd25bc
https://doi.org/10.1158/1078-0432.22466067

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Data from Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes

Purpose: We sought to investigate whether B cell receptor immunoglobulin (BcR IG) stereotypy is associated with particular clinicobiological features among chronic lymphocytic leukemia (CLL) patients expressing mutated BcR IG (M-CLL) encoded by the I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141c24fb06d5c3e1a7289bcc228ffa82
https://doi.org/10.1158/1078-0432.c.6526230

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