Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Xiao-bo Zhong"'
Autor:
Jing Jin, Le Tra Giang Nguyen, Andrew Wassef, Ragui Sadek, Timothy M. Schmitt, Grace L. Guo, Theodore P. Rasmussen, Xiao-bo Zhong
Publikováno v:
Non-Coding RNA, Vol 10, Iss 2, p 28 (2024)
The long non-coding RNA (lncRNA) hepatocyte nuclear factor-1 alpha (HNF1A) antisense RNA 1 (HNF1A-AS1) is an important lncRNA for liver growth, development, cell differentiation, and drug metabolism. Like many lncRNAs, HNF1A-AS1 has multiple annotate
Externí odkaz:
https://doaj.org/article/0ce28de94ac0487eb880b5c3eeb91e98
Autor:
Patrick K. T. Shiu, Mirolyuba Ilieva, Anja Holm, Shizuka Uchida, Johanna K. DiStefano, Agnieszka Bronisz, Ling Yang, Yoh Asahi, Ajay Goel, Liuqing Yang, Ashok Nuthanakanti, Alexander Serganov, Suresh K. Alahari, Chunru Lin, Barbara Pardini, Alessio Naccarati, Jing Jin, Beshoy Armanios, Xiao-bo Zhong, Nikolaos Sideris, Salih Bayraktar, Leandro Castellano, André P. Gerber, He Lin, Simon J. Conn, Doha Magdy Mostafa Sleem, Lisa Timmons
Publikováno v:
Non-Coding RNA, Vol 9, Iss 2, p 28 (2023)
We are delighted to share with you our twelfth Journal Club and highlight some of the most interesting papers published recently [...]
Externí odkaz:
https://doaj.org/article/b0a2bb4ed6c4486a86d0f0bf39d0dbe4
Autor:
Pei Wang, Xueyan Shao, Yifan Bao, Junjie Zhu, Liming Chen, Lirong Zhang, Xiaochao Ma, Xiao-bo Zhong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 171-185 (2020)
The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs) has been shown in obesity, the impacts of obese levels (overweight, obesity, and severe obes
Externí odkaz:
https://doaj.org/article/2d6d8b3eb3324aabb84355023ee4aadd
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 4, Pp 659-674 (2019)
Precision medicine is a rapidly-developing modality of medicine in human healthcare. Based on each patient׳s unique characteristics, more accurate dosages and drug selection can be made to achieve better therapeutic efficacy and less adverse reactio
Externí odkaz:
https://doaj.org/article/8ed9d8c408e441bbb1b778bf67a2bcf7
Autor:
Ai-Ming Yu, Magnus Ingelman-Sundberg, Nathan J. Cherrington, Lauren M. Aleksunes, Ulrich M. Zanger, Wen Xie, Hyunyoung Jeong, Edward M. Morgan, Peter J. Turnbaugh, Curtis D. Klaassen, Aadra P. Bhatt, Matthew R. Redinbo, Pengying Hao, David J. Waxman, Li Wang, Xiao-bo Zhong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 7, Iss 2, Pp 241-248 (2017)
Variations in drug metabolism may alter drug efficacy and cause toxicity; better understanding of the mechanisms and risks shall help to practice precision medicine. At the 21st International Symposium on Microsomes and Drug Oxidations held in Davis,
Externí odkaz:
https://doaj.org/article/2f3f00db456d41a9b0dff3480539d4d3
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0227102 (2019)
RNA modifications are recently emerged epigenetic modifications. These diverse RNA modifications have been shown to regulate multiple biological processes, including development. RNA modifications are dynamically controlled by the "writers, erasers,
Externí odkaz:
https://doaj.org/article/8d768d1e505548b0b8501b26d13e7681
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 6, Iss 5, Pp 384-392 (2016)
Isoniazid (INH) is highly effective for the management of tuberculosis. However, it can cause liver injury and even liver failure. INH metabolism has been thought to be associated with INH-induced liver injury. This review summarized the metabolic pa
Externí odkaz:
https://doaj.org/article/439e28328d654c8f9d3ddc334eb53a29
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 6, Iss 5, Pp 453-459 (2016)
The expression of phase-I drug metabolizing enzymes in liver changes dramatically during postnatal liver maturation. Farnesoid X receptor (FXR) is critical for bile acid and lipid homeostasis in liver. However, the role of FXR in regulating ontogeny
Externí odkaz:
https://doaj.org/article/9f1d68ff69df4853b43fe83250de6014
Publikováno v:
Non-Coding RNA, Vol 6, Iss 2, p 24 (2020)
Long noncoding RNAs (lncRNAs) are RNAs with a length of over 200 nucleotides that do not have protein-coding abilities. Recent studies suggest that lncRNAs are highly involved in physiological functions and diseases. lncRNAs HNF1α-AS1 and HNF4α-AS1
Externí odkaz:
https://doaj.org/article/e38bb7b6236c492e904bda4f47a2dbfc
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187557 (2017)
H19 RNA is highly expressed at early postnatal ages and precipitously decreases at a specific time corresponding with increases in expression of genes important for mature liver function, such as drug metabolizing enzymes. H19's role in the regulatio
Externí odkaz:
https://doaj.org/article/e2157780a26e48c5a9de3537024bf555