Synthesis and anti-α-glucosidase activity evaluation of betulinic acid derivatives

Autor: Xiao-Zheng Wu, Wen-Jian Zhu, Li Lu, Chun-Mei Hu, Ying-Ying Zheng, Xin Zhang, Jing Lin, Jing-Ying Wu, Zhuang Xiong, Kun Zhang, Xue-Tao Xu

Publikováno v: Arabian Journal of Chemistry, Vol 16, Iss 5, Pp 104659- (2023)

In this article, a series of betulinic acid derivatives (3a ∼ 3u, 4a ∼ 4e) were synthesized through a stepwise structure optimization and evaluated for their anti-α-glucosidase activities. All synthesized derivatives exhibited stronger anti-α-g

Externí odkaz: https://doaj.org/article/006370e018d54a35a40eaa0ed98f2939

In vitro and in silico studies of bis (indol-3-yl) methane derivatives as potential α-glucosidase and α-amylase inhibitors

Autor: Peng-Fei Zheng, Zhuang Xiong, Cui-ying Liao, Xin Zhang, Mei Feng, Xiao-Zheng Wu, Jing Lin, Lin-Sheng Lei, You-Cheng Zhang, Shao-Hua Wang, Xue-Tao Xu

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1938-1951 (2021)

In this paper, bis (indol-3-yl) methanes (BIMs) were synthesised and evaluated for their inhibitory activity against α-glucosidase and α-amylase. All synthesised compounds showed potential α-glucosidase and α-amylase inhibitory activities. Compou

Externí odkaz: https://doaj.org/article/2fde9f14d73e494daa4d6eb8a3c3078b

Synthesis and Biological Activity Evaluation of 2-Cyanopyrrole Derivatives as Potential Tyrosinase Inhibitors

Autor: Ya-Guang Hu, Zhu-Peng Gao, Ying-Ying Zheng, Chun-Mei Hu, Jing Lin, Xiao-Zheng Wu, Xin Zhang, Yong-Sheng Zhou, Zhuang Xiong, Dao-Yong Zhu

Publikováno v: Frontiers in Chemistry, Vol 10 (2022)

In order to find potential inhibitors of tyrosinase, two series of pyrrole derivatives A (1–17) and B (1–8) were synthesized and screened for their inhibitory activities on tyrosinase. Most of the 2-cyanopyrrole derivatives exhibited effective in

Externí odkaz: https://doaj.org/article/e7c3351d5070416680c492978b2851f8

In vitro and in silico studies of bis (indol-3-yl) methane derivatives as potential α-glucosidase and α-amylase inhibitors

Autor: Xin Zhang, Mei Feng, Lin-Sheng Lei, Xue-Tao Xu, Peng-Fei Zheng, Jing Lin, Xiao-Zheng Wu, Cui-ying Liao, Shao-Hua Wang, You-Cheng Zhang, Zhuang Xiong

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1938-1951 (2021)
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record

In this paper, bis (indol-3-yl) methanes (BIMs) were synthesised and evaluated for their inhibitory activity against α-glucosidase and α-amylase. All synthesised compounds showed potential α-glucosidase and α-amylase inhibitory activities. Compou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20345973742b84fce8793aa4f2564fc5
https://doaj.org/article/2fde9f14d73e494daa4d6eb8a3c3078b

Positron Annihilation Investigation on the Aged RS TiNi SMA

Autor: Jin Ping Zhang, Yu Qun Zhu, Xiao Zheng Wu, Shi Dong Wang, Hong Qi Xiong

Publikováno v: Materials Science Forum. :581-584

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16c721e2f45215d65c0315862946ab78
https://doi.org/10.4028/www.scientific.net/msf.175-178.581