Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xiao-Yi Lu"'
Autor:
Yi Ding, Qiu-Bing Chen, Hui Xu, Dilare Adi, Yi-Wen Ding, Wen-Jun Luo, Wen-Zhuo Zhu, Jia-Chen Xu, Xiaolu Zhao, Xiong-Jie Shi, Jie Luo, Hao Yin, Xiao-Yi Lu
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 9, Pp 100626- (2024)
Atherosclerotic cardiovascular disease is closely correlated with elevated low density lipoprotein-cholesterol. In feeding state, glucose and insulin activate mammalian target of rapamycin 1 that phosphorylates the deubiquitylase ubiquitin-specific p
Externí odkaz:
https://doaj.org/article/0b8673db0a7b4527a95eddd6d7a264a6
Autor:
Jian Xiao, Le-Wei Dong, Shuai Liu, Fan-Hua Meng, Chang Xie, Xiao-Yi Lu, Weiping J. Zhang, Jie Luo, Bao-Liang Song
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Niemann-Pick C1-like 1 (NPC1L1) is essential for intestinal cholesterol absorption. Together with the cholesterol-rich and Flotillin-positive membrane microdomain, NPC1L1 is internalized via clathrin-mediated endocytosis and transported to e
Externí odkaz:
https://doaj.org/article/f8e1015e759a442db518284ebdf1b709
Autor:
Jin-Kai Wang, Yang Li, Xiao-Lu Zhao, Yuan-Bin Liu, Jing Tan, Yu-Ying Xing, Dilare Adi, Yong-Tao Wang, Zhen-Yan Fu, Yi-Tong Ma, Song-Mei Liu, Yong Liu, Yan Wang, Xiong-Jie Shi, Xiao-Yi Lu, Bao-Liang Song, Jie Luo
Publikováno v:
Circulation. 145:675-687
Background: High blood cholesterol accelerates the progression of atherosclerosis, which is an asymptomatic process lasting for decades. Rupture of atherosclerotic plaques induces thrombosis, which results in myocardial infarction or stroke. Lowering
Autor:
Meiwen Yang, Zhi-Qi Guo, Xiao-Yi Luo, Zhao-Qiang Shen, Zi-Qing Xia, Chih-Ting Lu, Yue-Lin Sming Tsai, Yi-Zhong Fan
Publikováno v:
Journal of High Energy Physics, Vol 2024, Iss 10, Pp 1-33 (2024)
Abstract This study reanalyzes the detection prospects of dark matter (DM) annihilation signals in the Galactic Center, focusing on velocity-dependent dynamics within a spike density near the supermassive black hole (Sgr A⋆). We investigate three a
Externí odkaz:
https://doaj.org/article/095b4f9542a042fba30d435d42abd204
Autor:
Jie Luo, Wei Qi, Ao Hu, Ju-Qiong Wang, Yi Ding, Ming Sun, Xiongjie Shi, Bao-Liang Song, Xiao-Yi Lu, Wei Jiang, Xiaolu Zhao
Publikováno v:
Nature. 588:479-484
Cholesterol is an essential lipid and its synthesis is nutritionally and energetically costly1,2. In mammals, cholesterol biosynthesis increases after feeding and is inhibited under fasting conditions3. However, the regulatory mechanisms of cholester
Autor:
Yi-Tong Ma, Yan Wang, Jin-Kai Wang, Zhen-Yan Fu, Yu-Xia Zhou, Jian Wei, Dilare Adi, Ao Hu, Jie Luo, Ya-Jie Meng, Gulinaer Baituola, Xiao-Yi Lu, Bao-Liang Song, Xiang-Feng Lu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 39:2468-2479
Objective: A high level of LDL-C (low-density lipoprotein cholesterol) is a major risk factor for cardiovascular disease. The E3 ubiquitin ligase named IDOL (inducible degrader of the LDLR [LDL receptor]; also known as MYLIP [myosin regulatory light
Autor:
Ju-Qiong Wang, Liang-Liang Li, Ao Hu, Gang Deng, Jian Wei, Yun-Feng Li, Yuan-Bin Liu, Xiao-Yi Lu, Zhi-Ping Qiu, Xiong-Jie Shi, Xiaolu Zhao, Jie Luo, Bao-Liang Song
Publikováno v:
Nature. 608(7922)
High cholesterol is a major risk factor for cardiovascular disease
Publikováno v:
Frontiers of Information Technology & Electronic Engineering. 19:1230-1235
With the significant advancement in emerging processor, memory, and networking technologies, exascale systems will become available in the next few years (2020–2022). As the exascale systems begin to be deployed and used, there will be a continuous
Publikováno v:
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 44(13)
Extrusion-spheronisation method was used to prepare Rhus chinensis total phenolic acid pellets. The formula and preparation of R. chinensis total phenolic acid pellets were optimized. The formulas( drug loading capacity,diluent,wetting agent and anti
Autor:
Xiao-Ying, Wang, Hong, Lian, Xiao-Yi, Lu, Zhang-Wen, Xu, Wen, Xu, Miao, Ye, Wei, Xu, Hai-Yin, Zheng
Publikováno v:
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 44(11)
The intestinal absorption properties of four main effective components(gallic acid, ocinolglucoside, ethyl gallate and penta-O-galloyl-β-D-glucose) in Rhus chinensis extracts were investigated by in situ single-pass intestinal perfusion model in rat