Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Xiao-Xue Qin"'
Autor:
Dong-Xue Gan, Yi-Bei Wang, Ming-Yang He, Zi-Yang Chen, Xiao-Xue Qin, Zi-Wei Miao, Yu-Hua Chen, Bo Li
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
ObjectivesOrganotropism is primarily determined by tumor-derived exosomes. To date, the role of lung cancer cells-derived exosomes underlying the pre-metastatic niche formation is unclear.Materials and MethodsThe animal models of retro-orbital and in
Externí odkaz:
https://doaj.org/article/23b3fd35273a48ddb5d126684afc0516
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Tumor microenvironment (TME) plays a crucial role in the initiation and progression of lung adenocarcinoma (LUAD); however, there is still a challenge in understanding the dynamic modulation of the immune and stromal components in TME. In the present
Externí odkaz:
https://doaj.org/article/06e78b0f67584f3ba7f8f4c87a459073
Autor:
Shi-Yu Tang, Dong-Xin Liu, Yuan Li, Kang-Ji Wang, Xia-Fei Wang, Zheng-Kang Su, Wen-Gang Fang, Xiao-Xue Qin, Jia-Yi Wei, Wei-Dong Zhao, Yu-Hua Chen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
The expression of contactin-associated protein 1 (Caspr1) in brain microvascular endothelial cells (BMECs), one of the major cellular components of the neurovascular unit (NVU), has been revealed recently. However, the physiological role of Caspr1 in
Externí odkaz:
https://doaj.org/article/ad3751e724d3430e9cc47119b455b670
Autor:
Wei-Dong Zhao, Dong-Xin Liu, Jia-Yi Wei, Zi-Wei Miao, Ke Zhang, Zheng-Kang Su, Xue-Wei Zhang, Qiang Li, Wen-Gang Fang, Xiao-Xue Qin, De-Shu Shang, Bo Li, Qing-Chang Li, Liu Cao, Kwang Sik Kim, Yu-Hua Chen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Penetration of the blood–brain barrier (BBB) is crucial for development of E. coli-caused meningitis. Here, the authors show that a host membrane protein, Caspr1, acts as a receptor for a bacterial virulence factor to facilitate BBB penetration and
Externí odkaz:
https://doaj.org/article/2284a8655d2b415395c6982bdf49525d
Autor:
Xia-Fei Wang, Dong-Xin Liu, Yue Liang, Li-Li Xing, Wen-Hui Zhao, Xiao-Xue Qin, De-Shu Shang, Bo Li, Wen-Gang Fang, Liu Cao, Wei-Dong Zhao, Yu-Hua Chen
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161093 (2016)
Amyloid-β (Aβ), the major component of neuritic plaques in Alzheimer's disease (AD), is derived from sequential proteolytic cleavage of amyloid protein precursor (APP) by secretases. In this study, we found that cystatin C (CysC), a natural cystein
Externí odkaz:
https://doaj.org/article/8bb9b53c138841c8888f055c349765e8
Autor:
Yu-Hua Li, Yu-Hua Chen, Bo Li, Wen-Gang Fang, Li Wang, De-Shu Shang, Wei-Dong Zhao, Yan-Hua Wang, Hu Zhang, Dong-Xin Liu, Xiao-Xue Qin, Xiao-Ning Han, Zheng-Kang Su, Shu-Hong Zhang
Publikováno v:
Journal of Biological Chemistry. 294:6375-6386
Contactin-associated protein 1 (CASPR1 or CNTNAP1) was recently reported to be expressed in brain microvascular endothelial cells (BMECs), the major component of the blood–brain barrier. To investigate CASPR1′s physiological role in BMECs, here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0ba84ccc4543519d8360fd2906520b9
https://doi.org/10.1074/jbc.ra118.006263
https://doi.org/10.1074/jbc.ra118.006263
Autor:
Zi-Wei Miao, Xiao-Xue Qin, Yu-Hua Chen, Yi-Bei Wang, Dong-Xue Gan, Bo Li, Zi-Yang Chen, Ming-Yang He
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
ObjectivesOrganotropism is primarily determined by tumor-derived exosomes. To date, the role of lung cancer cells-derived exosomes underlying the pre-metastatic niche formation is unclear.Materials and MethodsThe animal models of retro-orbital and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc89555097fea866f30f226d2db3f92b
https://doi.org/10.3389/fcell.2020.591405
https://doi.org/10.3389/fcell.2020.591405
Autor:
Yuan, Li, Jia-Yi, Wei, Hui, Liu, Kang-Ji, Wang, Sheng-Nan, Jin, Zheng-Kang, Su, Hui-Jie, Wang, Jun-Xiu, Shi, Bo, Li, De-Shu, Shang, Wen-Gang, Fang, Xiao-Xue, Qin, Wei-Dong, Zhao, Yu-Hua, Chen
Publikováno v:
Cell Reports. 39:110656
Tight junctions (TJs) of brain microvascular endothelial cells (BMECs) play a pivotal role in maintaining the blood-brain barrier (BBB) integrity; however, precise regulation of TJs stability in response to physiological and pathological stimuli rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f8ab2d83e11afca7f39abad250abc3
https://doi.org/10.1016/j.celrep.2022.110656
https://doi.org/10.1016/j.celrep.2022.110656
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Tumor microenvironment (TME) plays a crucial role in the initiation and progression of lung adenocarcinoma (LUAD); however, there is still a challenge in understanding the dynamic modulation of the immune and stromal components in TME. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48206f0f9eb2b1b7bb3185a267b9bd9a
https://www.frontiersin.org/article/10.3389/fonc.2020.00424/full
https://www.frontiersin.org/article/10.3389/fonc.2020.00424/full
Autor:
Xiao-Xue Qin, Xia-Fei Wang, Wei-Dong Zhao, Yu-Hua Chen, Wen-Gang Fang, Dong-Xin Liu, Kang-Ji Wang, Zheng-Kang Su, Yuan Li, Shi-Yu Tang, Jia-Yi Wei
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
The expression of contactin-associated protein 1 (Caspr1) in brain microvascular endothelial cells (BMECs), one of the major cellular components of the neurovascular unit (NVU), has been revealed recently. However, the physiological role of Caspr1 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fba6491317c7d38b52f2a4558e2aeb8
https://www.frontiersin.org/article/10.3389/fnmol.2020.00023/full
https://www.frontiersin.org/article/10.3389/fnmol.2020.00023/full