Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Xiao-Tao Zhuo"'
Publikováno v:
Royal Society Open Science, Vol 7, Iss 5 (2020)
Herein, we report the first access of β-elemene derivatives through the SeO2-mediated oxidation reaction. Several new compounds were isolated through such a one-step reaction, and their structures were elucidated using various 2D-NMR techniques. Thi
Externí odkaz:
https://doaj.org/article/220fadb490834420bfcc3faa68170cd8
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 15:32-48
Background: Many human diseases are associated with dysregulation of HDACs. HDAC6 exhibits deacetylase activity not only to histone protein but also to non-histone proteins such as α- tubulin, HSP90, cortactin, and peroxiredoxin. These unique functi
Publikováno v:
Tetrahedron. 96:132402
Five- and six-membered aromatic rings bearing a methyl group are important molecular fragments in drug discovery. From the medicinal chemistry standpoint, the methyl group might play a pivotal role in improving the biological activities and druggabil
Publikováno v:
The Journal of Organic Chemistry. 76:6918-6924
An efficient strategy for the total synthesis of (+)-przewalskin B is reported. The key steps feature an intermolecular S(N)2' substitution of iodoallylic phosphate with organocupper reagent, a diastereoselective organocatalytic aldol cyclization, as
Publikováno v:
Chemistry - A European Journal. 15:6332-6334
Economic and practical advantages are offered by the iron(III)-catalyzed and air-mediated tandem coupling/hydroarylation/dehydrogenation of simple readily available aldehydes, alkynes, and amines for the synthesis of 2, 4-disubstituted quinolines (se
Publikováno v:
ChemInform. 40
Economic and practical advantages are offered by the iron(III)-catalyzed and air-mediated tandem coupling/hydroarylation/dehydrogenation of simple readily available aldehydes, alkynes, and amines for the synthesis of 2, 4-disubstituted quinolines (se