Zobrazeno 1 - 10
of 248
pro vyhledávání: '"Xiao-Song Wang"'
Autor:
Sanghoon Lee, Min Sun, Yiheng Hu, Yue Wang, Md N. Islam, David Goerlitz, Peter C. Lucas, Adrian V. Lee, Sandra M. Swain, Gong Tang, Xiao-Song Wang
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Multi-omics sequencing is poised to revolutionize clinical care in the coming decade. However, there is a lack of effective and interpretable genome-wide modeling methods for the rational selection of patients for personalized interventions.
Externí odkaz:
https://doaj.org/article/e9e5092c3b654f949089fcaec042ef9f
Autor:
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Haibo Yang, Fengqi Zhang, Xueping Zhu, Badi Zhou, Sean Yao, Aiko Nagayama, Sanghoon Lee, Jian Ouyang, Siang-Boon Koh, Eric L. Eisenhauer, Dominique Zarrella, Kate Lu, Bo R. Rueda, Lee Zou, Xiaofeng A. Su, Oladapo Yeku, Leif W. Ellisen, Xiao-Song Wang, Li Lan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Drugs targeting the DNA damage response (DDR) are widely used in cancer therapy, but resistance to these drugs remains a major clinical challenge. Here, we show that SYCP2, a meiotic protein in the synaptonemal complex, is aberrantly and com
Externí odkaz:
https://doaj.org/article/fee47f6ec5bd4fda828f917b06a525d3
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Objectives To reveal the association between a sedentary lifestyle and the prevalence of primary osteoporosis (POP).Design A community-based cross-sectional study was conducted.Setting This study was conducted in communities in Hefei city, Anhui prov
Externí odkaz:
https://doaj.org/article/84a1468c42a945989e5e7e5b5311cacd
Autor:
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Haibo Yang, Fengqi Zhang, Xueping Zhu, Badi Zhou, Sean Yao, Aiko Nagayama, Sanghoon Lee, Jian Ouyang, Siang-Boon Koh, Eric L. Eisenhauer, Dominique Zarrella, Kate Lu, Bo R. Rueda, Lee Zou, Xiaofeng A. Su, Oladapo Yeku, Leif W. Ellisen, Xiao-Song Wang, Li Lan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/e5d9d1b5c22f4da1876d5d6a6b5140cd
An integral genomic signature approach for tailored cancer therapy using genome-wide sequencing data
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Predicting drug responses in cancer patients requires robust computational frameworks. Here, the authors develop an integral genomic signature —iGenSig— approach to predict drug responses using multi-omics data from tumour samples, and validate t
Externí odkaz:
https://doaj.org/article/a489149cc0544d0fb901ddd22f7eea01
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 20, Iss 12, Pp 1066-1071 (2020)
Objective To summarize and analyze the data of postural balance and gait disorders in patients with Meige's syndrome (MS) who underwent subthalamic nucleus deep brain stimulation (STN ⁃ DBS). Methods The study included 14 patients with MS who under
Externí odkaz:
https://doaj.org/article/2cbe3cf6605f4ec293a96cb2e21e5880
Autor:
Li Li, Ling Lin, Jamunarani Veeraraghavan, Yiheng Hu, Xian Wang, Sanghoon Lee, Ying Tan, Rachel Schiff, Xiao-Song Wang
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-15 (2020)
Abstract Background Endocrine therapy is the most common treatment for estrogen receptor (ER)-positive breast cancer, but its effectiveness is limited by high rates of primary and acquired resistance. There are likely many genetic causes, and recent
Externí odkaz:
https://doaj.org/article/dd3f224ecac34744833aac2245b2fd71
Autor:
Xiao-Song Wang, Xiao-Jun Yu, Kang Wei, Shan-Xi Wang, Qi-Kun Liu, Ying-Guang Wang, Han Li, Cheng Huang
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Glioma is emerging as an aggressive type of glioma characterized by invasive growth pattern and dismal oncologic outcomes. microRNAs (miRNAs) have been attracting research attention in tumorigenesis. Herein, the aim of the current investigation was t
Externí odkaz:
https://doaj.org/article/ba90b31ee67d408b8383f77064449c05
Autor:
Xiao-Song Wang, Xi-Hai Xu, Gang Jiang, Yu-Huan Ling, Tian-Tian Ye, Yun-Wu Zhao, Kun Li, Yu-Ting Lei, Hua-Qing Hu, Ming-Wei Chen, Heng Wang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The prevalence of Helicobacter pylori infection is high worldwide, while numerous research has focused on unraveling the relationship between H. pylori infection and extragastric diseases. Although H. pylori infection has been associated with thyroid
Externí odkaz:
https://doaj.org/article/199abcae774747f9ba2fc258159aad7e
Autor:
Qing Feng, Du Long, Ming-shan Du, Xiao-song Wang, Zhen-shun Li, Yong-liang Zhao, Feng Qian, Yan Wen, Pei-wu Yu, Yan Shi
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundLaparoscopic gastrectomy (LG) has been increasingly used for the treatment of locally advanced Siewert type II and III adenocarcinoma of the esophagogastric junction (AEG). However, whether LG can achieve the same short-term efficacy in the
Externí odkaz:
https://doaj.org/article/7a46116f19cc44b4ba291a9471ce15ae