Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Xiao-Si Hu"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Alkene hydrodifluoroalkylation is a fruitful strategy for synthesizing medicinally relevant difluoromethylated molecules. Here, the authors report a Markovnikov hydrodifluoroalkylation of aryl and aliphatic alkenes using inexpensive Mg(ClO4)2·6H2O a
Externí odkaz:
https://doaj.org/article/e4d4b12b453c48aab89439a02d903c32
Autor:
Qing Pang, Lei Zhou, Xiao-Si Hu, Yong Wang, Zhong-Ran Man, Song Yang, Wei Wang, Zhen Qian, Hao Jin, Hui-Chun Liu
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Abstract We aimed to compare the efficacy of percutaneous transhepatic biliary stenting (PTBS) and PTBS combined with 125I particles implantation in the treatment of advanced extrahepatic cholangiocarcinoma (EHC). A total of 184 advanced EHC patients
Externí odkaz:
https://doaj.org/article/7200786a27bc4a498ebfb587058ea98a
Highly Stereoselective Positional Isomerization of Styrenes via Acid‐Catalyzed Carbocation Mechanism
Publikováno v:
Chinese Journal of Chemistry. 39:2227-2233
Publikováno v:
Advanced Synthesis & Catalysis. 362:4763-4793
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
Alkene hydrodifluoroalkylation is a fruitful strategy for synthesizing difluoromethylated compounds that are interesting for developing new medicinal agents, agrochemicals, and advanced materials. Whereas the anti-Markovnikov hydrodifluoroalkylation
Publikováno v:
Chemical Science. 11:97-106
We report the highly enantioselective synthesis of P-chiral tertiary phosphine oxides featuring an ethynyl group via Cu(I)-catalyzed azide–alkyne cycloaddition. Newly developed chiral pyridinebisoxazolines (PYBOX) bearing a bulky C4 shielding group
Publikováno v:
ACS Catalysis. 10:955-993
Optically active α-arylation carbonyl units are widely present in a wide variety of drugs, bioactive natural products, and valuable pharmacologically active molecules. Catalytic enantioselective α-...
Publikováno v:
Chinese Journal of Chemistry. 37:799-806
Publikováno v:
Chemical Communications. 55:13638-13648
The judicious incorporation of a fluoroalkyl moiety often brings about beneficial effects on the properties of bioactive molecules. Consequently, efficient methods for selective fluoroalkylation are much sought after in drug discovery. Despite signif
Publikováno v:
Organic & Biomolecular Chemistry. 17:9430-9434
A highly efficient metal-free aldol-type reaction of various acetals or ketals with fluorinated silyl enol ethers catalysed by less than 1 mol% HClO4 (70 wt%, aq.) is developed. This provides expedient access to a wide array of valuable fluoroalkyl e