Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Xiao-Ru HU"'
Autor:
Jing-jing Liu, Jian-bo Yang, Ying Wang, Xiao-ru Hu, Ya-dan Wang, Li-xing Nie, Feng Wei, Jian-dong Yu, Ling-wen Yao, Bei-lei Xu, Shuang-cheng Ma, Hong-yu Jin
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 767-780 (2024)
Context The mechanism of Renshen Shouwu Decoction (RSSW) in treating Alzheimer’s disease (AD) remains unknown.Objective This study investigates the effects and mechanism of RSSW for ameliorating AD.Materials and methods Ten SAMR1 mice and 40 SAMP8
Externí odkaz:
https://doaj.org/article/07c57c6d4d53483094f146f791806eb9
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Licorice (Glycyrrhiza spp.) is used widely in traditional Chinese medicine (TCM) due to its numerous pharmacologic effects. However, the mechanisms of action of the chemical constituents of licorice and their structure–function relationships are no
Externí odkaz:
https://doaj.org/article/c6fd5f49487b492891aac83d529a2777
Autor:
Ying CHEN, Xiao-Ru HU, Xian-Long CHENG, Shuang-Cheng MA, Qing-Sen RAN, Qing YANG, Wei-Jie QIANG, Zhong DAI, Xiao-Xin ZHU
Publikováno v:
Digital Chinese Medicine, Vol 1, Iss 4, Pp 261-271 (2018)
ABSTRACT: Objective This study was conducted to examine the absorption and translocation of conjugated bile acids (BAs) in Calculus bovis and its substitutes to detect differences in these materials.Methods A Caco-2 monolayer cell model was used to c
Externí odkaz:
https://doaj.org/article/e7676e9c1a80405e9d773d68474fb9ae
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Macrophages are a rich source of macrophage migration inhibitory factor (MIF). It is well established that macrophages and MIF play a pathogenic role in anti-glomerular basement membrane crescentic glomerulonephritis (anti-GBM CGN). However, whether
Externí odkaz:
https://doaj.org/article/85367f6a9a6b4aec9062c633cb631cdf
Autor:
Jian-Chun Li, Jian Jia, Li Dong, Zhong-Jing Hu, Xiao-Ru Huang, Hong-Lian Wang, Li Wang, Si-Jin Yang, Hui-Yao Lan
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 180-190 (2023)
Transforming growth factor β (TGF-β)/Smad3 plays a vital role in hypertensive cardiac fibrosis. The long non-coding RNA (lncRNA) Erbb4-IR is a novel Smad3-dependent lncRNA that mediates kidney fibrosis. However, the role of Erbb4-IR in hypertensive
Externí odkaz:
https://doaj.org/article/b8d482a02bc7412dad9db09ac27457d3
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 179:112979
The method of ultra-high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UHPLC-Q/TOF-MS) was established and combined with principal component analysis (PCA) to identify natural Calculus Bovis, in vitro cultured Calculu
Autor:
Liying Liang, Wenbiao Wang, Junzhe Chen, Wenjing Wu, Xiao-Ru Huang, Biao Wei, Yu Zhong, Ronald C. W. Ma, Xueqing Yu, Hui-Yao Lan
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/5d68d47ae1fb4e688b09bec1f05a05e7
Autor:
Wenjing Wu, Wenbiao Wang, Liying Liang, Junzhe Chen, Sifan Sun, Biao Wei, Yu Zhong, Xiao-Ru Huang, Jian Liu, Xiaoqin Wang, Xueqing Yu, Hui-Yao Lan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
“Cytokine storm” is common in critically ill COVID-19 patients, however, mechanisms remain largely unknown. Here, we reported that overexpression of SARS-CoV-2 N protein in diabetic db/db mice significantly increased tubular death and the release
Externí odkaz:
https://doaj.org/article/6b5b8846401a4f6ba697725cf8be026e
Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma
Autor:
Jeff Yat-Fai Chung, Philip Chiu-Tsun Tang, Max Kam-Kwan Chan, Vivian Weiwen Xue, Xiao-Ru Huang, Calvin Sze-Hang Ng, Dongmei Zhang, Kam-Tong Leung, Chun-Kwok Wong, Tin-Lap Lee, Eric W-F Lam, David J. Nikolic-Paterson, Ka-Fai To, Hui-Yao Lan, Patrick Ming-Kuen Tang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
TGF-β stimulated tumor-associated neutrophils (TANs) can exert pro-tumoral functions. Here the authors show that Smad3 activation in TANs is associated with an N2-like polarization state and poor outcome in patients with non-small cell lung carcinom
Externí odkaz:
https://doaj.org/article/ba3ca05e7ec94b9aa2d7bbddfdfd4bef
Publikováno v:
Natural Product Research. 27:1197-1201
A new eudesmanolide sesquiterpene, atractylenolide IV (1), together with seven known compounds were isolated from the 70% aqueous acetonic extract of the whole plant of Sarcandra glabra (Chloranthaceae). Their structures were established by spectral