Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Xiao-Ping Ye"'
Autor:
Chen-Yan Yan, Feng-Yao Wu, Feng Sun, Ya Fang, Rui-Jia Zhang, Chang-Run Zhang, Cao-Xu Zhang, Zheng Wang, Rui-Meng Yang, Liu Yang, Mei Dong, Qian-Yue Zhang, Xiao-Ping Ye, Huai-Dong Song, Shuang-Xia Zhao
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundISL LIM homeobox 2, also known as insulin gene enhancer protein ISL-2 (ISL2), is a transcription factor gene that participates in a wide range of developmental events. However, the role of ISL2 in the hypothalamus-pituitary-thyroid axis is
Externí odkaz:
https://doaj.org/article/7a8f1f2241c245beb06b935adfe28b4e
Autor:
Qian-Yue Zhang, Xiao-Ping Ye, Zheng Zhou, Chen-Fang Zhu, Rui Li, Ya Fang, Rui-Jia Zhang, Lu Li, Wei Liu, Zheng Wang, Shi-Yang Song, Sang-Yu Lu, Shuang-Xia Zhao, Jian-Nan Lin, Huai-Dong Song
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Hashimoto’s Thyroiditis is an autoimmune disease with a complex pathomechanism. Authors here show by single cell RNA sequencing that the thyroidal microenvironment in the disease is characterised by three stromal cell subtypes that are potentially
Externí odkaz:
https://doaj.org/article/9efe0aed643e40f0a6d940fc628988fe
Publikováno v:
FEBS Open Bio, Vol 11, Iss 5, Pp 1417-1427 (2021)
Thyroid dysgenesis (TD) is a major cause of primary congenital hypothyroidism; however, the molecular mechanism underlying this process is unclear. Current knowledge regarding the morphogenesis of the thyroid gland and vascular anomalies affecting th
Externí odkaz:
https://doaj.org/article/838de6c83ebe4a86bc81e55620d6d64e
Autor:
Sang-Yu Lu, Ying-Chao Chen, Jia-Lin Feng, Qin-Yi Zhou, Jing Chen, Chen-Fang Zhu, Miao-Miao Guo, Man-Man Zhang, Qian-Yue Zhang, Meng Lu, Liu Yang, Jing Wu, Shuang-Xia Zhao, Huai-Dong Song, Xiao-Ping Ye
Publikováno v:
International Journal of Endocrinology, Vol 2022 (2022)
Background. BRAF exon 15 p.V600E (BRAF V600E) mutation has been established as an important molecular marker for papillary thyroid carcinoma diagnosis by ultrasound-guided fine-needle aspiration biopsy (FNAB). Sanger sequencing is the gold standard f
Externí odkaz:
https://doaj.org/article/70cff3e2d5d24d968ae59897199e6d94
Autor:
He Jiang, Fei-Fei Yuan, Hai-Ning Wang, Wei Liu, Xiao-Ping Ye, Shao-Ying Yang, Hui-Jun Xie, Sha-Sha Yu, Yu-Ru Ma, Le-Le Zhang, Shuang-Xia Zhao, Huai-Dong Song, The China Consortium for the Genetics of Autoimmune Thyroid Disease
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Mutations in CD40 have been widely reported to be risk factors for Graves’ disease (GD). The gene, along with its cognate ligand CD40L, may regulate pro-inflammatory and immune responses. Rs1883832, located at the -1 position of the Kozak sequence,
Externí odkaz:
https://doaj.org/article/cf205bfd803540a3a5e7d83459702134
Autor:
Huang-Ming Cao, Xiao-Ping Ye, Jun-Hua Ma, He Jiang, Sheng-Xian Li, Rong-Ying Li, Xue-Song Li, Cui-Cui Guo, Zhi-Quan Wang, Ming Zhan, Chun-Lin Zuo, Chun-Ming Pan, Shuang-Xia Zhao, Cui-Xia Zheng, Huai-Dong Song
Publikováno v:
EBioMedicine, Vol 2, Iss 11, Pp 1718-1724 (2015)
Adipokines such as leptin play important roles in the regulation of energy metabolism, particularly in the control of appetite. Here, we describe a hormone, mimecan, which is abundantly expressed in adipose tissue. Mimecan was observed to inhibit foo
Externí odkaz:
https://doaj.org/article/46f4d2ab4766441496cf91b30447b6e6
Autor:
Feng Cheng, Ruimeng Yang, Bing Han, Mei Dong, Huai-Dong Song, Feng Sun, Rui-Jia Zhang, Xiao-Ping Ye, Ya Fang, Shuang-Xia Zhao
Publikováno v:
Clinical Genetics. 100:713-721
DUOX2 is the most frequently mutated gene in patients with congenital hypothyroidism (CH) in China. However, no reliable genotype-phenotype relationship has been found in patients with DUOX2 mutations. In this study, DUOX2 mutations were screened in
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 11, Iss 5, Pp 1417-1427 (2021)
FEBS Open Bio, Vol 11, Iss 5, Pp 1417-1427 (2021)
Thyroid dysgenesis (TD) is a major cause of primary congenital hypothyroidism; however, the molecular mechanism underlying this process is unclear. Current knowledge regarding the morphogenesis of the thyroid gland and vascular anomalies affecting th
Autor:
Chun-Lin Zuo, Sha-Sha Yu, Jun Liang, Guan-Qi Gao, Hui-Jun Xie, Zheng Zhou, Huai-Dong Song, Fei-Fei Yuan, Yu-Ru Ma, Wen-Hua Du, Feng Sun, Qian-Yue Zhang, Chang-Run Zhang, Shuang-Xia Zhao, Xiao-Ping Ye, Wei Liu, Lu Li, Guoyue Yuan, Ying-Xia Ying
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 105:e2600-e2608
Context Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) are the 2 main autoimmune thyroid diseases that have both similarities and differences. Determining the genetic basis that distinguishes HT from GD is key for a better understanding of
Autor:
Sang-Yu, Lu, Ying-Chao, Chen, Jia-Lin, Feng, Qin-Yi, Zhou, Jing, Chen, Chen-Fang, Zhu, Miao-Miao, Guo, Man-Man, Zhang, Qian-Yue, Zhang, Meng, Lu, Liu, Yang, Jing, Wu, Shuang-Xia, Zhao, Huai-Dong, Song, Xiao-Ping, Ye
Publikováno v:
International journal of endocrinology. 2022
Thyroid fine-needle aspiration samples from 278 patients with 310 thyroid nodules were collected. Sanger sequencing and ddPCR were conducted to detect theTheddPCR has higher sensitivity than Sanger sequencing and we propose ddPCR as a supplement to S