Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Xiao-Ming Xia"'
Publikováno v:
eLife, Vol 7 (2018)
Mammalian BK-type voltage- and Ca2+-dependent K+ channels are found in a wide range of cells and intracellular organelles. Among different loci, the composition of the extracellular microenvironment, including pH, may differ substantially. For exampl
Externí odkaz:
https://doaj.org/article/e4914e1dfaca458aa1a6d34ee0030065
Autor:
Pedro L Martinez-Espinosa, Jianping Wu, Chengtao Yang, Vivian Gonzalez-Perez, Huifang Zhou, Hongwu Liang, Xiao-Ming Xia, Christopher J Lingle
Publikováno v:
eLife, Vol 4 (2015)
Two mammalian genes, Kcnt1 and Kcnt2, encode pore-forming subunits of Na+-dependent K+ (KNa) channels. Progress in understanding KNa channels has been hampered by the absence of specific tools and methods for rigorous KNa identification in native cel
Externí odkaz:
https://doaj.org/article/3e7131681543466e9bccd504328f46df
Autor:
Christoph Brenker, Yu Zhou, Astrid Müller, Fabio Andres Echeverry, Christian Trötschel, Ansgar Poetsch, Xiao-Ming Xia, Wolfgang Bönigk, Christopher J Lingle, U Benjamin Kaupp, Timo Strünker
Publikováno v:
eLife, Vol 3 (2014)
Sperm are equipped with a unique set of ion channels that orchestrate fertilization. In mouse sperm, the principal K+ current (IKSper) is carried by the Slo3 channel, which sets the membrane potential (Vm) in a strongly pHi-dependent manner. Here, we
Externí odkaz:
https://doaj.org/article/e83017a040674c3d9b166ab38e277594
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6135 (2009)
The pH and voltage-regulated Slo3 K(+) channel, a homologue of the Ca(2+)- and voltage-regulated Slo1 K(+) channel, is thought to be primarily expressed in sperm, but the properties of Slo3 studied in heterologous systems differ somewhat from the nat
Externí odkaz:
https://doaj.org/article/1d8e486f0a5f4506a8d450d482e4c834
Publikováno v:
In Biomedical Signal Processing and Control January 2022 71 Part B
Publikováno v:
In Biocybernetics and Biomedical Engineering July-September 2021 41(3):1140-1149
Autor:
Haryadi, Bagus, Liou, Juin J., Wei, Hai-Cheng, Xiao, Ming-Xia, Wu, Hsien-Tsai, Sun, Cheuk-Kwan
Publikováno v:
In Computer Methods and Programs in Biomedicine November 2018 166:115-121
Publikováno v:
Proc Natl Acad Sci U S A
The tremorgenic fungal alkaloid paxilline (PAX) is a commonly used specific inhibitor of the large-conductance, voltage- and Ca 2+ -dependent BK-type K + channel. PAX inhibits BK channels by selective interaction with closed states. BK inhibition by
Publikováno v:
The Journal of General Physiology
Martinez-Espinosa et al. show that FGF14 and the voltage-dependent Na+ channel Nav1.3 are the main regulators of rapidly inactivating currents and Nav channel availability in mouse adrenal chromaffin cells. Their results uncover a role for FGF14 in r
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