Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Xiao-Lin YU"'
Autor:
Ling-Jie Li, Xiao-Ying Sun, Ya-Ru Huang, Shuai Lu, Yu-Ming Xu, Jing Yang, Xi-Xiu Xie, Jie Zhu, Xiao-Yun Niu, Dan Wang, Shi-Yu Liang, Xiao-Yu Du, Sheng-Jie Hou, Xiao-Lin Yu, Rui-Tian Liu
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-17 (2024)
Abstract Background Deoxyribonuclease 2 (DNase II) plays a key role in clearing cytoplasmic double-stranded DNA (dsDNA). Deficiency of DNase II leads to DNA accumulation in the cytoplasm. Persistent dsDNA in neurons is an early pathological hallmark
Externí odkaz:
https://doaj.org/article/7a9b0bec679c43d4b8d1202c43f3c6dc
Autor:
Sheng-jie Hou, Ya-ru Huang, Jie Zhu, Ying-bo Jia, Xiao-yun Niu, Jin-ju Yang, Xiao-lin Yu, Xiao-yu Du, Shi-yu Liang, Fang Cui, Ling-jie Li, Chen Tian, Rui-tian Liu
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract The elderly frequently present impaired blood–brain barrier which is closely associated with various neurodegenerative diseases. However, how the albumin, the most abundant protein in the plasma, leaking through the disrupted BBB, contribu
Externí odkaz:
https://doaj.org/article/f9daa4180fdd4446bfb2696aee353476
Autor:
Xiao-ying Sun, Xiao-lin Yu, Jie Zhu, Ling-jie Li, Lun Zhang, Ya-ru Huang, Dong-qun Liu, Mei Ji, Xun Sun, Ling-xiao Zhang, Wei-wei Zhou, Dongming Zhang, Jianwei Jiao, Rui-tian Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Passive immunotherapy is one of the most promising interventions for Alzheimer’s disease (AD). However, almost all immune-modulating strategies fail in clinical trials with unclear causes although they attenuate neuropathology and cognitiv
Externí odkaz:
https://doaj.org/article/e1dfffcdcd3a499c9362a619cc60c54a
Autor:
Xin-Long Huo, Shu-Fang Wang, Qing Yang, Xiao-Lin Yu, Tao Gu, Hai-Xia Hua, Mo Yang, Li-Li Bai, Xiao-Lu Zhang
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 61, Iss 1, Pp 96-101 (2022)
Objective: To investigate whether genomic instability (GI)-derived long non-coding RNAs (lncRNAs) have a prognostic impact on the patients with endometrial cancer. Material and methods: Patients with Uterine Corpus Endometrial Carcinoma (UCEC) were s
Externí odkaz:
https://doaj.org/article/8e7843ef1d5b40a898604d4948b7bf28
Autor:
Xiao-Lin Yu, Qian Zhao, Fen Liu, Yu-Juan Yuan, Bin-Bin Fang, Xue-He Zhang, Wen-Ling Li, Xiao-Mei Li, Guo-Li Du, Xiao-Ming Gao, Yi-Ning Yang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Metabolic syndrome (MetS) is a major risk factor for cardiovascular disease and negatively affecting the prognosis of patients with ST elevation myocardial infarction (STEMI). Macrophage migration inhibitory factor (MIF) is a multipotent cytokine inv
Externí odkaz:
https://doaj.org/article/f6fdb843a3af4d1f91586c569da4d33c
Autor:
Xiao-ying Sun, Ling-jie Li, Quan-Xiu Dong, Jie Zhu, Ya-ru Huang, Sheng-jie Hou, Xiao-lin Yu, Rui-tian Liu
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Background Tau pathology is a hallmark of Alzheimer’s disease (AD) and other tauopathies. During disease progression, abnormally phosphorylated forms of tau aggregate and accumulate into neurofibrillary tangles, leading to synapse loss, ne
Externí odkaz:
https://doaj.org/article/6b577e9e1eee4e68bb1f8166bdba0d99
Autor:
Xiao-ge Liu, Lun Zhang, Shuai Lu, Dong-qun Liu, Ya-ru Huang, Jie Zhu, Wei-wei Zhou, Xiao-lin Yu, Rui-tian Liu
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. No disease-modifying strategy to prevent or delay AD progression currently exists. Aβ oligomers (AβOs), rather than monomers or fibrils, are considered as t
Externí odkaz:
https://doaj.org/article/96ff639954c94c9cba334d83b238166b
Autor:
Jing Tao, Xiao-Lin Yu, Yu-Juan Yuan, Xin Shen, Jun Liu, Pei-Pei Gu, Zhao Wang, Yi-Tong Ma, Guo-Qing Li
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
Insulin resistance (IR) plays a critical role in cardiovascular diseases and metabolic diseases. In this study, we identified the downregulation of DMRT2 in adipose tissues from insulin-resistant subjects through bioinformatics analysis and in an ins
Externí odkaz:
https://doaj.org/article/3f1a300ee3af4787a3895a485745336a
Autor:
Meng-Jiao Shao, Jun-yi Luo, Jia Shi, Fen Liu, Chun-fang Shan, Fan Luo, Xiao-lin Yu, Qian Zhao, Ting Tian, Xiao-Mei Li, Yi-ning Yang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Obesity is an independent risk factor for cardiovascular disease. We investigated whether and to what extent visceral obesity-related indices were associated with coronary collateralization (CC) in chronic total occlusion (CTO) patients.M
Externí odkaz:
https://doaj.org/article/28894430af994fde987a00db6d232142
Autor:
Ya-ru Huang, Xi-xiu Xie, Mei Ji, Xiao-lin Yu, Jie Zhu, Ling-xiao Zhang, Xiao-ge Liu, Chen Wei, Gang Li, Rui-tian Liu
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 202-217 (2019)
It has been suggested that aggregation of α-synuclein (α-syn) into oligomers leads to neurodegeneration in Parkinson's disease (PD), but intravenous immunoglobulin (IVIG) which contains antibodies against α-syn monomers and oligomers fails to trea
Externí odkaz:
https://doaj.org/article/e32fd0b6658847ebacb36342141d1ef6