Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Xiao-Li Wei"'
Autor:
Xiao-Li Wei, Fu-Rong Liu, Ji-Hong Liu, Hong-Yun Zhao, Yang Zhang, Zhi-Qiang Wang, Miao-Zhen Qiu, Fei Xu, Qiu-Qiong Yu, Yi-Wu Du, Yan-Xia Shi, De-Sheng Wang, Feng-Hua Wang, Rui-Hua Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
PIK3CA is a commonly mutated cancer-associated gene, making it an attractive therapeutic target. Here, the authors report the results of a first-in-human phase Ia trial to assess the safety and recommended phase II dose of CYH33, a PI3Kα inhibitor,
Externí odkaz:
https://doaj.org/article/e1f16c3559294902ac1b66c1f48464a7
Autor:
Ji-Chao Zhou, Cai-Cai Jin, Xiao-Li Wei, Rui-Bing Xu, Ruo-Yu Wang, Zhi-Meng Zhang, Bo Tang, Jin-Mei Yu, Jiao-Jiao Yu, Shuang Shang, Xiao-Xi Lv, Fang Hua, Ping-Ping Li, Zhuo-Wei Hu, Yong-Mei Shen, Feng-Peng Wang, Xiu-Ying Ma, Bing Cui, Fu-Neng Geng, Xiao-Wei Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Aberrant mitophagy has been identified as a driver for energy metabolism disorder in most cardiac pathological processes. However, finding effective targeted agents and uncovering their precise modulatory mechanisms remain unconquered. Fuzi, the late
Externí odkaz:
https://doaj.org/article/ac2647d0d2cd476885f204369d00439a
Autor:
You-Zhu Li, Na Li, Wen-Sheng Liu, Yan-Wei Sha, Rong-Feng Wu, Ya-Ling Tang, Xing-Shen Zhu, Xiao-Li Wei, Xiao-Ya Zhang, Yi-Feng Wang, Zhong-Xian Lu, Fu-Xing Zhang
Publikováno v:
Asian Journal of Andrology, Vol 24, Iss 1, Pp 67-72 (2022)
Acephalic spermatozoa syndrome is a rare type of teratozoospermia that severely impairs the reproductive ability of male patients, and genetic defects have been recognized as the main cause of acephalic spermatozoa syndrome. Spermatogenesis and centr
Externí odkaz:
https://doaj.org/article/a1a372cafa8e473295585e85c4943234
Autor:
Yi-Xin Yin, Yi-Hong Ling, Xiao-Li Wei, Cai-Yun He, Bing-Zhi Wang, Chun-Fang Hu, Wen-Ping Lin, Run-Cong Nie, Jie-Wei Chen, Jin-Long Lin, Jie Zhou, Juan-Juan Xie, Jing-Ping Yun, Dan Xie, Li-Yan Xue, Mu-Yan Cai
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundEpstein-Barr virus-associated gastric cancer (EBVaGC) exhibits unique histological characteristics within the immune-cell-rich microenvironment, but the role of tertiary lymphoid structure (TLS) in EBVaGC is not yet fully understood.Methods
Externí odkaz:
https://doaj.org/article/e386f1e9a203425c806c3595ee5ffbc5
Autor:
Xiao-Li Wei, Xuan Luo, Hui Sheng, Yun Wang, Dong-Liang Chen, Jia-Ning Li, Feng-Hua Wang, Rui-Hua Xu
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-10 (2020)
Abstract Background The outcomes of immune checkpoint inhibitors in cancer patients with liver metastases are poor, which may be related to a different tumor microenvironment in liver metastases from primary tumors. This study was aimed to analyze PD
Externí odkaz:
https://doaj.org/article/d2aa0de49595497fac12c61cd5d8ff1f
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
The general immune landscape of nasopharyngeal carcinoma (NPC) renders immunotherapy suitable for patients with NPC. Immune checkpoint inhibitors (ICIs) based on programmed death-1/programmed death ligand-1 (PD-1/PD-L1) blockade have made a breakthro
Externí odkaz:
https://doaj.org/article/21696740c4054901a1c538d1e170f3e3
Autor:
Jian-Ying Xu, Wen-Long Guan, Shi-Xun Lu, Xiao-Li Wei, Wen-Jie Shi, Chao Ren, Yu-Hong Li, Sheng-Ping Li, Miao-Zhen Qiu, Feng-Hua Wang
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 16 (2022)
Background: Pancreatic acinar cell carcinoma (PACC) is rare, and its appropriate treatment remains unknown. We aim to explore the characteristics and optimal treatment of it. Methods: The data on clinicopathologic characteristics, molecular alteratio
Externí odkaz:
https://doaj.org/article/36e401668b8242b3b4a644ac891c241e
Autor:
Xiao‐Li Wei, Chao Ren, Feng‐Hua Wang, Yang Zhang, Hong‐Yun Zhao, Ben‐Yan Zou, Zhi‐Qiang Wang, Miao‐Zhen Qiu, Dong‐Sheng Zhang, Hui‐Yan Luo, Feng Wang, Sheng Yao, Rui‐Hua Xu
Publikováno v:
Cancer Communications, Vol 40, Iss 8, Pp 345-354 (2020)
Abstract Background Several programmed cell death ligand 1 (PD‐L1)/programmed cell death protein 1 (PD‐1) antibodies have been approved for cancer treatment worldwide. Their pharmacokinetic and pharmacodynamic characteristics have been reported m
Externí odkaz:
https://doaj.org/article/8ce01e25a806447a911986d71c98652a
Autor:
Xiao-Li Wei, Tian-Qi Luo, Jia-Ning Li, Zhi-Cheng Xue, Yun Wang, You Zhang, Ying-Bo Chen, Chuan Peng
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Background: Dysregulation of lipid metabolism plays important roles in the tumorigenesis and progression of gastric cancer (GC). The present study aimed to establish a prognostic model based on the lipid metabolism–related genes in GC patients.Mate
Externí odkaz:
https://doaj.org/article/dbe7a1c1fe194ba1a5f2c4ca8c54d3bc
Autor:
Xiao-Li Wei, Jian-Ying Xu, De-Shen Wang, Dong-Liang Chen, Chao Ren, Jia-Ning Li, Feng Wang, Feng-Hua Wang, Rui-Hua Xu
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: We previously reported tumor mutation burden (TMB) as a potential prognostic factor for patients with advanced gastric cancer (AGC) receiving immunotherapy. We aimed to comprehensively understand the impact of tumor burden and TMB on effi
Externí odkaz:
https://doaj.org/article/e5ad0c44f30a452888450f3d2d278979